His primary areas of investigation include RNA, Biochemistry, Oligonucleotide, DNA and Nucleic acid. His studies in RNA integrate themes in fields like Molecular biology and Steric effects. Masad J. Damha focuses mostly in the field of Biochemistry, narrowing it down to topics relating to Derivatization and, in certain cases, Phase, Molecule and Chemical synthesis.
His study focuses on the intersection of Oligonucleotide and fields such as Stereochemistry with connections in the field of Oligoribonucleotides, A-DNA and Nuclease. Masad J. Damha interconnects Amino acid, Crystallography and Counterion in the investigation of issues within DNA. The concepts of his Nucleic acid study are interwoven with issues in Dendrimer, Phosphoramidite and Enzyme.
His scientific interests lie mostly in RNA, Oligonucleotide, Stereochemistry, Biochemistry and Nucleic acid. His RNA research is multidisciplinary, incorporating elements of Molecular biology and DNA. His work in the fields of Oligonucleotide, such as Phosphoramidite, intersects with other areas such as Solid-phase synthesis.
He has researched Stereochemistry in several fields, including Oligoribonucleotides, Phosphodiester bond, Guanine and Ribose. His Nucleic acid structure, Enzyme, Nucleic acid thermodynamics and Messenger RNA study, which is part of a larger body of work in Biochemistry, is frequently linked to Linker, bridging the gap between disciplines. Masad J. Damha studied Nucleic acid and Small interfering RNA that intersect with RNA interference.
Masad J. Damha mostly deals with RNA, Biochemistry, Nucleic acid, DNA and Stereochemistry. The study incorporates disciplines such as DNA microarray, Oligonucleotide, NAD+ kinase and Nucleotide in addition to RNA. Many of his research projects under Oligonucleotide are closely connected to Linker with Linker, tying the diverse disciplines of science together.
His research in the fields of RNase P, Intron, Binding site and RNase H overlaps with other disciplines such as Context. In his study, which falls under the umbrella issue of Nucleic acid, Guide RNA is strongly linked to Computational biology. His research integrates issues of Combinatorial chemistry and Biophysics in his study of DNA.
RNA, Biochemistry, DNA, Stereochemistry and Nucleic acid are his primary areas of study. His RNA study combines topics in areas such as Mutant and Intron. His DNA research includes themes of Biophysics and Nuclear magnetic resonance spectroscopy.
His Stereochemistry research incorporates elements of RNase P, RNase H, Nucleotide and A-DNA. His Nucleic acid research is multidisciplinary, incorporating perspectives in Cas9, CRISPR and Guide RNA. His study in Oligonucleotide is interdisciplinary in nature, drawing from both Thermal stability, Fluorine and Nucleoside.
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Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing
Glen F. Deleavey;Masad J. Damha.
Chemistry & Biology (2012)
Chemically modified siRNA: tools and applications
Jonathan K Watts;Glen F Deleavey;Masad J Damha.
Drug Discovery Today (2008)
Fiber-Optic DNA Sensor for Fluorometric Nucleic Acid Determination
Paul A. E. Piunno;Ulrich J. Krull;Robert H. E. Hudson;Masad J. Damha.
Analytical Chemistry (1995)
HYBRIDS OF RNA AND ARABINONUCLEIC ACIDS (ANA AND 2'F-ANA) ARE SUBSTRATES OF RIBONUCLEASE H
M. J. Damha;C. J. Wilds;A. Noronha;I. Brukner.
Journal of the American Chemical Society (1998)
Fiber optic biosensor for fluorimetric detection of DNA hybridization
Paul A.E. Piunno;Ulrich J. Krull;Robert H.E. Hudson;Masad J. Damha.
Analytica Chimica Acta (1994)
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis
Masad J. Damha;Paul A. Giannaris;Steven V. Zabarylo.
Nucleic Acids Research (1990)
Improvements in siRNA properties mediated by 2′-deoxy-2′-fluoro-β- d -arabinonucleic acid (FANA)
Thomas Dowler;Denis Bergeron;Anna-Lisa Tedeschi;Luc Paquet.
Nucleic Acids Research (2006)
2′-Deoxy-2′-fluoro-β-d-arabinonucleosides and oligonucleotides (2′F-ANA): synthesis and physicochemical studies
Christopher J. Wilds;Masad J. Damha.
Nucleic Acids Research (2000)
Nucleic acid dendrimers: novel biopolymer structures
Robert H. E. Hudson;Masad J. Damha.
Journal of the American Chemical Society (1993)
Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.
Keith T. Gagnon;Hannah M. Pendergraff;Glen F. Deleavey;Eric E. Swayze.
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