D-Index & Metrics Best Publications
Biology and Biochemistry
France
2023
Medicine
France
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 110 Citations 49,147 601 World Ranking 3211 National Ranking 81
Biology and Biochemistry D-index 112 Citations 49,934 596 World Ranking 607 National Ranking 10

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in France Leader Award

2023 - Research.com Biology and Biochemistry in France Leader Award

2006 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

2003 - Member of the European Academy of Sciences

1998 - Fellow of the American Academy of Arts and Sciences

1990 - Member of Academia Europaea

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

Pierre Corvol mainly investigates Internal medicine, Endocrinology, Angiotensin II, Renin–angiotensin system and Biochemistry. The study incorporates disciplines such as Pharmacology and In vivo in addition to Internal medicine. His Endocrinology research includes elements of Receptor and In situ hybridization.

His Angiotensin II research integrates issues from Hypothalamus and Signal transduction. As a member of one scientific family, he mostly works in the field of Renin–angiotensin system, focusing on Kidney and, on occasion, Pathology. His study focuses on the intersection of Enzyme and fields such as Angiotensin-converting enzyme with connections in the field of Molecular biology, Gene targeting, Gene, Chinese hamster ovary cell and Molecular cloning.

His most cited work include:

  • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. (3268 citations)
  • Molecular basis of human hypertension: Role of angiotensinogen (1680 citations)
  • PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1) (1161 citations)

What are the main themes of his work throughout his whole career to date?

Internal medicine, Endocrinology, Renin–angiotensin system, Biochemistry and Angiotensin II are his primary areas of study. His study in Plasma renin activity, Blood pressure, Kidney, Angiotensin-converting enzyme and Essential hypertension is carried out as part of his Internal medicine studies. The various areas that Pierre Corvol examines in his Blood pressure study include Surgery and Cardiology.

His Endocrinology research incorporates elements of Receptor, In situ hybridization and Cell biology. The Renin–angiotensin system study combines topics in areas such as Molecular biology, Radioimmunoassay, Antibody and Pharmacology. His work deals with themes such as Complementary DNA, Gene expression, Messenger RNA and Gene, which intersect with Molecular biology.

He most often published in these fields:

  • Internal medicine (50.53%)
  • Endocrinology (47.96%)
  • Renin–angiotensin system (38.91%)

What were the highlights of his more recent work (between 2002-2021)?

  • Internal medicine (50.53%)
  • Endocrinology (47.96%)
  • Renin–angiotensin system (38.91%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Internal medicine, Endocrinology, Renin–angiotensin system, Angiotensin II and Angiogenesis. He interconnects Missense mutation and In situ hybridization in the investigation of issues within Internal medicine. His Endocrinology study combines topics in areas such as Mutation, Receptor and In vivo.

His Renin–angiotensin system research is multidisciplinary, relying on both Fetus, Kidney, Pharmacology and Cell biology. Pierre Corvol has researched Angiotensin II in several fields, including Aldosterone, Bradykinin and Enzyme. His work on ACE inhibitor as part of general Angiotensin-converting enzyme study is frequently connected to Angiotensin-converting enzyme 2, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

Between 2002 and 2021, his most popular works were:

  • Mutations in the SDHB Gene Are Associated with Extra-adrenal and/or Malignant Phaeochromocytomas (440 citations)
  • Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. (328 citations)
  • Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma (273 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Pierre Corvol spends much of his time researching Internal medicine, Endocrinology, Renin–angiotensin system, Angiogenesis and Angiotensin II. His studies deal with areas such as Surgery and Cell growth as well as Internal medicine. His Endocrinology research is multidisciplinary, incorporating perspectives in Receptor, Chinese hamster ovary cell and In vivo.

The various areas that he examines in his Renin–angiotensin system study include Kidney, Anuria and Potter sequence. His Angiogenesis study combines topics from a wide range of disciplines, such as Endothelial stem cell, Vascular endothelial growth factor and In situ hybridization. His Angiotensin II research includes themes of Aldosterone, Angiotensin-converting enzyme, Bradykinin and Enzyme.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

B Rigat;C Hubert;F Alhenc-Gelas;F Cambien.
Journal of Clinical Investigation (1990)

4923 Citations

Molecular basis of human hypertension: Role of angiotensinogen

Xavier Jeunemaitre;Florent Soubrier;Yuri V. Kotelevtsev;Richard P. Lifton;Richard P. Lifton.
Cell (1992)

2501 Citations

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

Brigitte Rigat;Christine Hubert;Pierre Corvol;Florent Soubrier.
Nucleic Acids Research (1992)

1884 Citations

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

L Tiret;B Rigat;S Visvikis;C Breda.
American Journal of Human Genetics (1992)

1701 Citations

Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

Alain Bonnardeaux;Eleanor Davies;Xavier Jeunemaitre;Isabelle Fery.
Hypertension (1994)

1164 Citations

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

Florent Soubrier;Francois Alhenc-Gelas;Christine Hubert;Jacqueline Allegrini.
Proceedings of the National Academy of Sciences of the United States of America (1988)

1010 Citations

Mutations in the SDHB Gene Are Associated with Extra-adrenal and/or Malignant Phaeochromocytomas

Anne-Paule Gimenez-Roqueplo;Judith Favier;Pierre Rustin;Claudine Rieubland.
Cancer Research (2003)

630 Citations

Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene.

Christine Hubert;Anne-Marie Houot;Pierre Corvol;Florent Soubrier.
Journal of Biological Chemistry (1991)

586 Citations

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway.

Anne-Paule Gimenez-Roqueplo;Judith Favier;Pierre Rustin;Jean-Jacques Mourad.
American Journal of Human Genetics (2001)

492 Citations

Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis.

Judith C. Sluimer;Jean-Marie Gasc;Job L. van Wanroij;Natasja Kisters.
Journal of the American College of Cardiology (2008)

490 Citations

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