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Pierre Corvol

Pierre Corvol

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
117
Citations
55945
World Ranking
717
National Ranking
11

Medicine

D-Index
117
Citations
56592
World Ranking
4177
National Ranking
124

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • 2006 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale
  • 2003 - Member of the European Academy of Sciences
  • 1998 - Fellow of the American Academy of Arts and Sciences
  • 1990 - Member of Academia Europaea

Overview

Pierre Corvol is affiliated with the Collège de France in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Nephrology, and Physiology. The main topics covered in their work include Renal and related cancers, Genetic and Kidney Cyst Diseases, Renal Diseases and Glomerulopathies, Pediatric Urology and Nephrology Studies, Lysosomal Storage Disorders Research, Complement system in diseases, and the Lymphatic System and Diseases.

The scientist has published in several venues, with frequent appearances in Pediatric Nephrology, Kidney International, Journal of the American Society of Nephrology, Human Molecular Genetics, and JCI Insight. Key recent papers include:

  • Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss, 2020, Journal of the American Society of Nephrology
  • Bi-allelic pathogenic variations in DNAJB11 cause Ivemark II syndrome, a renal-hepatic-pancreatic dysplasia, 2020, Kidney International
  • Bi-allelic mutations in renin-angiotensin system genes, associated with renal tubular dysgenesis, can also present as a progressive chronic kidney disease, 2020, Pediatric Nephrology
  • Development of an automated estimation of foot process width using deep learning in kidney biopsies from patients with Fabry, minimal change, and diabetic kidney diseases, 2023, Kidney International
  • Signaling pathways predisposing to chronic kidney disease progression, 2020, JCI Insight

Frequent collaborators include Laurence Heidet, Sophie Saunier, Behzad Najafian, Camilla Tøndel, and Einar Svarstad.

Recognition includes the Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale in 2006, membership in the European Academy of Sciences since 2003, fellowship at the American Academy of Arts and Sciences since 1998, and membership in Academia Europaea since 1990.

Best Publications

  • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

    B Rigat;C Hubert;F Alhenc-Gelas;F Cambien

  • Molecular basis of human hypertension: Role of angiotensinogen

    Xavier Jeunemaitre;Florent Soubrier;Yuri V. Kotelevtsev;Richard P. Lifton;Richard P. Lifton

  • PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

    Brigitte Rigat;Christine Hubert;Pierre Corvol;Florent Soubrier

  • Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

    L Tiret;B Rigat;S Visvikis;C Breda

  • Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

    Alain Bonnardeaux;Eleanor Davies;Xavier Jeunemaitre;Isabelle Fery

  • Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

    Florent Soubrier;Francois Alhenc-Gelas;Christine Hubert;Jacqueline Allegrini

  • Mutations in the SDHB Gene Are Associated with Extra-adrenal and/or Malignant Phaeochromocytomas

    Anne-Paule Gimenez-Roqueplo;Judith Favier;Pierre Rustin;Claudine Rieubland

  • A molecular variant of angiotensinogen associated with preeclampsia

    Ward K;Hata A;Jeunemaitre X;Helin C

  • Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene.

    Christine Hubert;Anne-Marie Houot;Pierre Corvol;Florent Soubrier

  • Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis.

    Judith C. Sluimer;Jean-Marie Gasc;Job L. van Wanroij;Natasja Kisters

  • The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway.

    Anne-Paule Gimenez-Roqueplo;Judith Favier;Pierre Rustin;Jean-Jacques Mourad

  • The two homologous domains of human angiotensin I-converting enzyme are both catalytically active.

    Lei Wei;Frangois Alhenc-Gelas;Pierre Corvol;Eric Clauser

  • Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review

    Z. Lenkei;M. Palkovits;P. Corvol;C. Llorens-Cortès

  • Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.

    Sylvie Zini;Marie-Claude Fournie-Zaluski;Eric Chauvel;Bernard P. Roques

  • Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain

    Annabelle Reaux;Nadia De Mota;Ivana Skultetyova;Zsolt Lenkei

  • The Hemoregulatory Peptide N-Acetyl-Ser-Asp-Lys-Pro Is a Natural and Specific Substrate of the N-terminal Active Site of Human Angiotensin-converting Enzyme

    Anne Rousseau;Annie Michaud;Marie-Thérèse Chauvet;Maryse Lenfant

  • Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline.

    M Azizi;A Rousseau;E Ezan;T T Guyene

  • Haplotypes of angiotensinogen in essential hypertension.

    Xavier Jeunemaitre;Ituro Inoue;Christopher Williams;Anne Charru

  • Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma

    Sébastien Le Jan;Céline Amy;Aurélie Cazes;Catherine Monnot

  • PCR DETECTION OF THE INSERTION/ DELETION POLYMORPHISM OF THE HUMAN ANGIOTENSIN CONVERTING ENZYME GENE

    B Rigat;C Hubert;P Corvol;F Soubrier

Frequent Co-Authors

Florent Soubrier
Florent Soubrier Université Paris Cité
Eric Clauser
Eric Clauser Université Paris Cité
Xavier Jeunemaitre
Xavier Jeunemaitre Université Paris Cité
Pierre-François Plouin
Pierre-François Plouin Université Paris Cité
Gilles Chatellier
Gilles Chatellier Université Paris Cité
Genevieve Evin
Genevieve Evin University of Melbourne
Bernard P. Roques
Bernard P. Roques Université Paris Cité
Marie-Claude Fournie-Zaluski
Marie-Claude Fournie-Zaluski Grenoble Alpes University
Jean-Baptiste Michel
Jean-Baptiste Michel University of Lorraine

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