Bernard P. Roques

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Best Publications

• Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.

  Hans W. D. Matthes;Rafael Maldonado;Frédéric Simonin;Olga Valverde

  2126
  Citations

• Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB1 Receptor Knockout Mice

  Catherine Ledent;Olga Valverde;Gregorio Cossu;François Petitet

  1536
  Citations

• High-affinity enkephalin-degrading peptidase in brain is increased after morphine

  B. Malfroy;J. P. Swerts;A. Guyon;B. P. Roques

  918
  Citations

• The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

  B P Roques;M C Fournié-Zaluski;E Soroca;J M Lecomte

  855
  Citations

• Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

  Rafael Maldonado;Adolfo Saiardi;Olga Valverde;Tarek A. Samad

  600
  Citations

• Disruption of the κ-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ-agonist U-50,488H and attenuates morphine withdrawal

  Frédéric Simonin;Olga Valverde;Claire Smadja;Susan Slowe

  588
  Citations

• First glimpses at structure-function relationships of the nucleocapsid protein of retroviruses.

  Jean-Luc Darlix;Mary Lapadat-Tapolsky;Hugues de Rocquigny;Bernard P. Roques

  588
  Citations

• The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

  Etienne Jacotot;Luigi Ravagnan;Markus Loeffler;Karine F. Ferri

  578
  Citations

• International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors.

  Florence Noble;Stephen A. Wank;Jacqueline N. Crawley;Jacques Bradwejn

  503
  Citations

• Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.

  Sylvie Zini;Marie-Claude Fournie-Zaluski;Eric Chauvel;Bernard P. Roques

  449
  Citations

• Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding.

  Ketan S. Gajiwala;Hua Chen;Fabrice Cornille;Bernard P. Roques

  399
  Citations

• Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB

  Rafael Maldonado;Julie A. Blendy;Eleni Tzavara;Peter Gass

  391
  Citations

• Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

  Etienne E. Jacotot;Karine K.F. Ferri;Chahrazed C. El Hamel;Catherine C. Brenner

  350
  Citations

• Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin

  S. Yamasaki;A. Baumeister;T. Binz;J. Blasi

  313
  Citations

• NCp7 Activates HIV-1Lai RNA Dimerization by Converting a Transient Loop-Loop Complex into a Stable Dimer

  Delphine Muriaux;Hugues De Rocquigny;Bernard-Pierre Roques;Jacques Paoletti

  258
  Citations

• Autoradiographic distribution of mu and delta opiate receptors in rat brain using highly selective ligands

  R. Quirion;J.M. Zajac;J.L. Morgat;B.P. Roques

  253
  Citations

• Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.

  Marie-Claude Fournie-Zaluski;Pierre Chaillet;Romaine Bouboutou;Annie Coulaud

  250
  Citations

• Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain

  Gilles Waksman;Edith Hamel;Marie-Claude Fournie-Zaluski;Bernard P. Roques

  248
  Citations

• Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.

  Bernard P. Roques;Marie-Claude Fournié-Zaluski;Michel Wurm

  247
  Citations

• CCK-B receptor: chemistry, molecular biology, biochemistry and pharmacology

  Florence Noble;Bernard P. Roques

  234
  Citations