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Bernard P. Roques

Bernard P. Roques

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
46643
World Ranking
1001
National Ranking
18

Bernard P. Roques publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Bernard P. Roques sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 773 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Bernard P. Roques D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Bernard P. Roques sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 109 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Bernard P. Roques is affiliated with Grenoble Alpes University in France, and their research spans several interconnected fields, including Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work primarily addresses topics related to neuropeptides, peptidase inhibition, pain mechanisms, receptor signaling, and Alzheimer's disease research.

Their recent research outputs include publications across notable scientific venues such as the Proceedings of the National Academy of Sciences, European Journal of Medicinal Chemistry, Acta Neuropathologica, Biochemical Journal, and the Journal of Hypertension.

Noteworthy publications by Bernard P. Roques are:

  • Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects (2021, Proceedings of the National Academy of Sciences)
  • Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules (2022, European Journal of Medicinal Chemistry)
  • Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brain (2021, Acta Neuropathologica)
  • Structural insight into the catalytic mechanism and inhibitor binding of aminopeptidase A (2020, Biochemical Journal)
  • BRAIN-PENETRATING AMINOPEPTIDASE A INHIBITORS FOR NEW TREATMENT OF HYPERTENSION AND HEART FAILURE (2021, Journal of Hypertension)

Their frequent co-authors include Catherine Llorens-Cortés, Ram Kandasamy, Todd M. Hillhouse, Kathryn E. Livingston, and Kelsey Kochan. These collaborations support multidisciplinary approaches across neuroscience, pharmacology, and molecular biology.

Bernard P. Roques' research topics often focus on:

  • Neuropeptides and Animal Physiology
  • Peptidase Inhibition and Analysis
  • Pain Mechanisms and Treatments
  • Receptor Mechanisms and Signaling
  • Alzheimer's disease research and treatments
  • 14-3-3 protein interactions
  • Signaling Pathways in Disease

Their work integrates several subfields such as Cellular and Molecular Neuroscience, Oncology, Molecular Biology, Physiology, and Endocrinology, Diabetes, and Metabolism, highlighting a multidisciplinary scientific approach.

Best Publications

  • Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.

    Hans W. D. Matthes;Rafael Maldonado;Frédéric Simonin;Olga Valverde

  • Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB1 Receptor Knockout Mice

    Catherine Ledent;Olga Valverde;Gregorio Cossu;François Petitet

  • High-affinity enkephalin-degrading peptidase in brain is increased after morphine

    B. Malfroy;J. P. Swerts;A. Guyon;B. P. Roques

  • The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

    B P Roques;M C Fournié-Zaluski;E Soroca;J M Lecomte

  • Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

    Rafael Maldonado;Adolfo Saiardi;Olga Valverde;Tarek A. Samad

  • Disruption of the κ-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ-agonist U-50,488H and attenuates morphine withdrawal

    Frédéric Simonin;Olga Valverde;Claire Smadja;Susan Slowe

  • First glimpses at structure-function relationships of the nucleocapsid protein of retroviruses.

    Jean-Luc Darlix;Mary Lapadat-Tapolsky;Hugues de Rocquigny;Bernard P. Roques

  • The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

    Etienne Jacotot;Luigi Ravagnan;Markus Loeffler;Karine F. Ferri

  • International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors.

    Florence Noble;Stephen A. Wank;Jacqueline N. Crawley;Jacques Bradwejn

  • Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.

    Sylvie Zini;Marie-Claude Fournie-Zaluski;Eric Chauvel;Bernard P. Roques

  • Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding.

    Ketan S. Gajiwala;Hua Chen;Fabrice Cornille;Bernard P. Roques

  • Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB

    Rafael Maldonado;Julie A. Blendy;Eleni Tzavara;Peter Gass

  • Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2

    Etienne E. Jacotot;Karine K.F. Ferri;Chahrazed C. El Hamel;Catherine C. Brenner

  • Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin

    S. Yamasaki;A. Baumeister;T. Binz;J. Blasi

  • NCp7 Activates HIV-1Lai RNA Dimerization by Converting a Transient Loop-Loop Complex into a Stable Dimer

    Delphine Muriaux;Hugues De Rocquigny;Bernard-Pierre Roques;Jacques Paoletti

  • Autoradiographic distribution of mu and delta opiate receptors in rat brain using highly selective ligands

    R. Quirion;J.M. Zajac;J.L. Morgat;B.P. Roques

  • Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.

    Marie-Claude Fournie-Zaluski;Pierre Chaillet;Romaine Bouboutou;Annie Coulaud

  • Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain

    Gilles Waksman;Edith Hamel;Marie-Claude Fournie-Zaluski;Bernard P. Roques

  • Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.

    Bernard P. Roques;Marie-Claude Fournié-Zaluski;Michel Wurm

  • CCK-B receptor: chemistry, molecular biology, biochemistry and pharmacology

    Florence Noble;Bernard P. Roques

Frequent Co-Authors

Marie-Claude Fournie-Zaluski
Marie-Claude Fournie-Zaluski Grenoble Alpes University
Florence Noble
Florence Noble Université Paris Cité
Rafael Maldonado
Rafael Maldonado Pompeu Fabra University
Yves Mély
Yves Mély University of Strasbourg
Pierre Corvol
Pierre Corvol Collège de France
Olga Valverde
Olga Valverde Pompeu Fabra University
Robert A. Bambara
Robert A. Bambara University of Rochester
Guido Kroemer
Guido Kroemer Université Paris Cité
Johan Hoebeke
Johan Hoebeke Centre national de la recherche scientifique, CNRS
Jean-Baptiste Michel
Jean-Baptiste Michel University of Lorraine

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