Brigitte L. Kieffer

Research.com Recognitions

• 2004 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for her pioneering work on the molecular neurobiology of opioid-controlled behaviors the results of which have very important implications,,for the treatment of pain drug abuse and emotional disorders."

Overview

Best Publications

• Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.

  Hans W. D. Matthes;Rafael Maldonado;Frédéric Simonin;Olga Valverde

  2126
  Citations

• The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.

  Brigitte L. Kieffer;Katia Befort;Claire Gaveriaux-Ruff;Christian G. Hirth

  1496
  Citations

• Reward Processing by the Opioid System in the Brain

  Julie Le Merrer;Jérôme A. J. Becker;Katia Befort;Brigitte L. Kieffer

  1088
  Citations

• Exploring the opioid system by gene knockout.

  Brigitte L Kieffer;Claire Gavériaux-Ruff

  855
  Citations

• Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses

  Dominique Filliol;Sandy Ghozland;Johanna Chluba;Miguel Martin

  787
  Citations

• Opioids: first lessons from knockout mice.

  Brigitte L. Kieffer

  673
  Citations

• Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor Gene

  Anna Moles;Brigitte L. Kieffer;Francesca R. D'Amato

  599
  Citations

• Disruption of the κ-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ-agonist U-50,488H and attenuates morphine withdrawal

  Frédéric Simonin;Olga Valverde;Claire Smadja;Susan Slowe

  588
  Citations

• Opioid receptors: distinct roles in mood disorders

  Pierre-Eric Lutz;Brigitte L. Kieffer;Brigitte L. Kieffer;Brigitte L. Kieffer

  546
  Citations

• Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides

  Brigitte L. Kieffer

  542
  Citations

• Atrial G protein-activated K+ channel: expression cloning and molecular properties.

  N Dascal;W Schreibmayer;N F Lim;W Wang

  522
  Citations

• Dissociation of the opioid receptor mechanisms that control mechanical and heat pain.

  Grégory Scherrer;Noritaka Imamachi;Yu-Qing Cao;Candice Contet

  521
  Citations

• Mu opioid receptor: a gateway to drug addiction.

  Candice Contet;Brigitte L Kieffer;Katia Befort

  395
  Citations

• mu-Opioid receptor knockout mice do not self-administer alcohol.

  Amanda J. Roberts;Jeffrey S. McDonald;Charles J. Heyser;Brigitte L. Kieffer

  376
  Citations

• Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus

  Christine Tuffereau;Jacqueline Bénéjean;Danielle Blondel;Brigitte Kieffer

  355
  Citations

• The delta opioid receptor: an evolving target for the treatment of brain disorders

  Amynah A. Pradhan;Katia Befort;Chihiro Nozaki;Claire Gavériaux-Ruff

  350
  Citations

• A Single Nucleotide Polymorphic Mutation in the Human μ-Opioid Receptor Severely Impairs Receptor Signaling

  Katia Befort;Dominique Filliol;Fabien M. Décaillot;Claire Gavériaux-Ruff

  340
  Citations

• Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C.

  Gang Pei;B. L. Kieffer;R. J. Lefkowitz;N. J. Freedman

  322
  Citations

• Motivational Effects of Cannabinoids Are Mediated by μ-Opioid and κ-Opioid Receptors

  Sandy Ghozland;Hans W. D. Matthes;Frederic Simonin;Dominique Filliol

  316
  Citations

• kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system

  Frederic Simonin;Claire Gaveriaux-Ruff;Katia Befort;Hans Matthes

  314
  Citations