World's Best Scientists 2026 revealed!
Brigitte L. Kieffer

Brigitte L. Kieffer

D-Index & Metrics

Medicine

D-Index
93
Citations
33162
World Ranking
10856
National Ranking
335

Brigitte L. Kieffer publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Brigitte L. Kieffer sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 331 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Brigitte L. Kieffer D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Brigitte L. Kieffer sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 93 D-Index — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 2004 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for her pioneering work on the molecular neurobiology of opioid-controlled behaviors the results of which have very important implications,,for the treatment of pain drug abuse and emotional disorders."

Overview

Brigitte L. Kieffer is affiliated with the University of Strasbourg in France. Their research primarily spans the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology, with a focus on specialized subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Cognitive Neuroscience, and Psychiatry and Mental Health.

Their work delves into several main scientific topics, including:

  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Pain Mechanisms and Treatments
  • Functional Brain Connectivity Studies
  • Stress Responses and Cortisol

Kieffer has contributed research published in a variety of scientific venues, notably:

  • Biological Psychiatry
  • Journal of Medicinal Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eNeuro
  • Scientific Reports

Recent publications associated with Kieffer include:

  • "Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement," 2024, Nature
  • "Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus," 2020, eNeuro
  • "Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY," 2020, eNeuro
  • "μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors," 2020, eNeuro
  • "The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs," 2020, eLife

Frequent collaborators include:

  • Emmanuel Darcq
  • Sami Ben Hamida
  • Florence Allain
  • Md Toufiqur Rahman
  • Chunyang Jin

Kieffer received the Richard Lounsbery Award from the National Academy of Sciences and the French Academy of Sciences in 2004. The award citation highlights their pioneering work on the molecular neurobiology of opioid-controlled behaviors with implications for the treatment of pain, drug abuse, and emotional disorders.

Best Publications

  • Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.

    Hans W. D. Matthes;Rafael Maldonado;Frédéric Simonin;Olga Valverde

  • The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.

    Brigitte L. Kieffer;Katia Befort;Claire Gaveriaux-Ruff;Christian G. Hirth

  • Reward Processing by the Opioid System in the Brain

    Julie Le Merrer;Jérôme A. J. Becker;Katia Befort;Brigitte L. Kieffer

  • Exploring the opioid system by gene knockout.

    Brigitte L Kieffer;Claire Gavériaux-Ruff

  • Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses

    Dominique Filliol;Sandy Ghozland;Johanna Chluba;Miguel Martin

  • Opioids: first lessons from knockout mice.

    Brigitte L. Kieffer

  • Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor Gene

    Anna Moles;Brigitte L. Kieffer;Francesca R. D'Amato

  • Disruption of the κ-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective κ-agonist U-50,488H and attenuates morphine withdrawal

    Frédéric Simonin;Olga Valverde;Claire Smadja;Susan Slowe

  • Opioid receptors: distinct roles in mood disorders

    Pierre-Eric Lutz;Brigitte L. Kieffer;Brigitte L. Kieffer;Brigitte L. Kieffer

  • Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides

    Brigitte L. Kieffer

  • Atrial G protein-activated K+ channel: expression cloning and molecular properties.

    N Dascal;W Schreibmayer;N F Lim;W Wang

  • Dissociation of the opioid receptor mechanisms that control mechanical and heat pain.

    Grégory Scherrer;Noritaka Imamachi;Yu-Qing Cao;Candice Contet

  • Mu opioid receptor: a gateway to drug addiction.

    Candice Contet;Brigitte L Kieffer;Katia Befort

  • mu-Opioid receptor knockout mice do not self-administer alcohol.

    Amanda J. Roberts;Jeffrey S. McDonald;Charles J. Heyser;Brigitte L. Kieffer

  • Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus

    Christine Tuffereau;Jacqueline Bénéjean;Danielle Blondel;Brigitte Kieffer

  • The delta opioid receptor: an evolving target for the treatment of brain disorders

    Amynah A. Pradhan;Katia Befort;Chihiro Nozaki;Claire Gavériaux-Ruff

  • A Single Nucleotide Polymorphic Mutation in the Human μ-Opioid Receptor Severely Impairs Receptor Signaling

    Katia Befort;Dominique Filliol;Fabien M. Décaillot;Claire Gavériaux-Ruff

  • Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C.

    Gang Pei;B. L. Kieffer;R. J. Lefkowitz;N. J. Freedman

  • Motivational Effects of Cannabinoids Are Mediated by μ-Opioid and κ-Opioid Receptors

    Sandy Ghozland;Hans W. D. Matthes;Frederic Simonin;Dominique Filliol

  • kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system

    Frederic Simonin;Claire Gaveriaux-Ruff;Katia Befort;Hans Matthes

Frequent Co-Authors

Claire Gaveriaux-Ruff
Claire Gaveriaux-Ruff University of Strasbourg
Rafael Maldonado
Rafael Maldonado Pompeu Fabra University
Ian Kitchen
Ian Kitchen University of Surrey
Christopher J. Evans
Christopher J. Evans University of California, Los Angeles
Amanda J. Roberts
Amanda J. Roberts Scripps Research Institute
George F. Koob
George F. Koob National Institute on Drug Abuse
Pierre Paoletti
Pierre Paoletti École Normale Supérieure
Andrée Dierich
Andrée Dierich Institute of Genetics and Molecular and Cellular Biology
Allan I. Basbaum
Allan I. Basbaum University of California, San Francisco
Ipek Yalcin
Ipek Yalcin Centre national de la recherche scientifique, CNRS

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