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Genetics

D-Index
78
Citations
32035
World Ranking
1673
National Ranking
218

Overview

Janet Shipley is affiliated with the Institute of Cancer Research in the United Kingdom and has a research profile focused on oncology, molecular biology, and cancer diagnostics. Their work spans medicine and biochemistry, genetics, and molecular biology, with notable contributions to pulmonary and respiratory medicine as well as pathology and forensic medicine.

Their research covers several specialized subfields including oncology, cancer research, sarcoma diagnosis and treatment, and protein degradation and inhibitors. Specific main topics include:

  • Sarcoma Diagnosis and Treatment
  • Tumors and Oncological Cases
  • CAR-T Cell Therapy Research
  • Protein Degradation and Inhibitors
  • Cancer Genomics and Diagnostics
  • Lymphoma Diagnosis and Treatment
  • Bone Tumor Diagnosis and Treatments

Janet Shipley collaborates frequently with several coauthors, reflecting continued partnerships in cancer research:

  • Anna Kelsey
  • Susanne A. Gatz
  • Julia Chisholm
  • Joanna Selfe
  • Meriel Jenney

Their scholarly output is regularly published in journals with a strong focus on cancer and molecular research. Frequent publication venues include:

  • Cancers
  • Cancer Research
  • Pediatric Blood & Cancer
  • European Journal of Cancer
  • Nature Communications

Several recent papers authored or coauthored by Shipley highlight areas of genomic classification, risk stratification, and molecular testing in oncology, particularly focusing on sarcomas and testicular cancers. These include:

  • "Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium" (2021) published in Journal of Clinical Oncology
  • "Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe" (2020) published in Pediatric Blood & Cancer
  • "Genomic landscape of platinum resistant and sensitive testicular cancers" (2020) published in Nature Communications
  • "Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe" (2022) published in European Journal of Cancer
  • "Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response" (2021) published in Cancer Research

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

    J Clark;P J Rocques;A J Crew;S Gill

  • A census of amplified and overexpressed human cancer genes

    Thomas Santarius;Janet Shipley;Daniel Brewer;Michael R. Stratton

  • Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.

    A.J. Crew;J. Clark;C. Fisher;S. Gill

  • Fusion Gene-Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma

    Daniel Williamson;Edoardo Missiaglia;Aurélien de Reyniès;Gaëlle Pierron

  • Testicular germ-cell cancer

    Alan Horwich;Janet Shipley;Robert Huddart

  • Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma.

    J Clark;YJ Lu;SK Sidhar;C Parker

  • PAX3/FOXO1 Fusion Gene Status Is the Key Prognostic Molecular Marker in Rhabdomyosarcoma and Significantly Improves Current Risk Stratification

    Edoardo Missiaglia;Dan Williamson;Julia Chisholm;Pratyaksha Wirapati

  • The t(X;1)(p11.2;q21.2) Translocation in Papillary Renal Cell Carcinoma Fuses a Novel Gene PRCC to the TFE3 Transcription Factor Gene

    SK Sidhar;J Clark;S Gill;RA Hamoudi

  • Poorly differentiated synovial sarcoma: an analysis of clinical, pathologic, and molecular genetic features.

    van de Rijn M;Barr Fg;Xiong Qb;Hedges M

  • Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma.

    J. Clark;H. Benjamin;S. Gill;Sanjiu Sidhar

  • Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene.

    Leendert H.J. Looijenga;Remko Hersmus;Ad J.M. Gillis;Rolph Pfundt

  • Gains, Losses, and Amplification of Genomic Material in Rhabdomyosarcoma Analyzed by Comparative Genomic Hybridization

    Stephen Weber-Hall;John Anderson;Aidan McManus;Syuiti Abe

  • Genes, chromosomes, and rhabdomyosarcoma

    John Anderson;Anthony Gordon;Kathy Pritchard-Jones;Janet Shipley

  • Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia

    Yong-Jie Lu;Pinchas Osin;Sunil R. Lakhani;Silvana Di Palma

  • The SYT Protein Involved in the t(X;18) Synovial Sarcoma Translocation is a Transcriptional Activator Localised in Nuclear Bodies

    David Brett;Suzanna Whitehouse;Per Antonson;Janet Shipley

  • Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

    Kevin Litchfield;Brenda Summersgill;Shawn E Yost;Razvan Sultana

  • Gain of 1q Is Associated with Adverse Outcome in Favorable Histology Wilms’ Tumors

    Sandra Hing;Yong-Jie Lu;Brenda Summersgill;Linda King-Underwood

  • Amplification and Overexpression of the KIT Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults

    Alan McIntyre;Brenda Summersgill;Beata Grygalewicz;Ad J.M. Gillis

  • EPIGENETICS AND GENETICS A census of amplified and overexpressed human cancer genes

    T Santarius;J Shipley;D Brewer;M. R Stratton

Frequent Co-Authors

Kathy Pritchard-Jones
Kathy Pritchard-Jones University College London
Robert Huddart
Robert Huddart Institute of Cancer Research
Cyril Fisher
Cyril Fisher Royal Marsden NHS Foundation Trust
Olivier Delattre
Olivier Delattre PSL University
Colin Cooper
Colin Cooper University of East Anglia
Richard S. Houlston
Richard S. Houlston Institute of Cancer Research
Clare Turnbull
Clare Turnbull Institute of Cancer Research
Gilles Vassal
Gilles Vassal Institut Gustave Roussy
Rogier Versteeg
Rogier Versteeg University of Amsterdam
Torsten Pietsch
Torsten Pietsch University of Bonn

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