World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
132
Citations
68268
World Ranking
379
National Ranking
250

Medicine

D-Index
133
Citations
68949
World Ranking
2213
National Ranking
1248

Overview

David E. Fisher is affiliated with Harvard University in the United States. Their research activity spans multiple fields with a strong focus on biochemistry, genetics, molecular biology, and medicine. The primary subfields include molecular biology, oncology, immunology, cell biology, and geometry and topology.

The scientist's research topics cover a range of specialized areas related to skin biology and cancer immunotherapy. Notable areas of focus are:

  • Melanin and skin pigmentation
  • Geometric and algebraic topology
  • Cancer immunotherapy and biomarkers
  • Cutaneous melanoma detection and management
  • Immunotherapy and immune responses
  • Melanoma and MAPK pathways
  • CAR-T cell therapy research

David E. Fisher has contributed to several prominent publications, frequently appearing in journals such as:

  • Journal of Investigative Dermatology
  • arXiv (Cornell University)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Hematology/Oncology Clinics of North America

Significant papers authored or co-authored by Fisher include:

  • "Treatment of Advanced Melanoma in 2020 and Beyond" (2020), Journal of Investigative Dermatology
  • "Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells" (2020), Nature
  • "Skin pigmentation and its control: From ultraviolet radiation to stem cells" (2020), Experimental Dermatology
  • "Targeting TBK1 to overcome resistance to cancer immunotherapy" (2023), Nature
  • "B-cell-specific checkpoint molecules that regulate anti-tumour immunity" (2023), Nature

The scientist has collaborated frequently with peers such as Jennifer A. Lo, Lajos V. Kemény, Keith T. Flaherty, Inbal Rachmin, and Akinori Kawakami, reflecting an interdisciplinary and multi-institutional approach to their research.

In addition to journal articles, David E. Fisher has authored several books published by Materials Research Foundations. These books include titles related to materials science and technology such as "Recycling of Rare Earths," "Graphene Composite Supercapacitor Electrodes," "Metallurgy of Lightweighting," "Data-Mining and Intermetallic Property-Prediction," "Transparent Metals," and "Calcium-Ion Batteries," with publication years ranging from 2022 to 2025.

Best Publications

  • Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.

    Sterne Jac.;S Murthy;J V Diaz

  • p53 status and the efficacy of cancer therapy in vivo

    SW Lowe;S Bodis;A McClatchey;L Remington

  • Apoptosis in cancer therapy: Crossing the threshold

    David E. Fisher

  • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

    Levi A. Garraway;Hans R. Widlund;Mark A. Rubin;Gad Getz

  • Being big or growing fast: systematic review of size and growth in infancy and later obesity

    Janis Baird;David Fisher;Patricia Lucas;Jos Kleijnen

  • Melanocyte biology and skin pigmentation

    Jennifer Y. Lin;David E. Fisher

  • MITF: master regulator of melanocyte development and melanoma oncogene

    Carmit Levy;Mehdi Khaled;David E. Fisher

  • Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial

    Timothyn Stanley Maughan;Richard Alexander Adams;Chris Smith;Angela M. Meade

  • In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

    Robert T. Manguso;Robert T. Manguso;Hans W. Pope;Hans W. Pope;Margaret D. Zimmer;Margaret D. Zimmer;Flavian D. Brown

  • BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

    Dennie Tompers Frederick;Adriano Piris;Alexandria P. Cogdill;Zachary A. Cooper

  • Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability

    Gaël G. McGill;Martin Horstmann;Hans R. Widlund;Jinyan Du

  • Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche

    Emi K. Nishimura;Emi K. Nishimura;Scott R. Granter;Scott R. Granter;David E. Fisher;David E. Fisher

  • Chromatin structure analyses identify miRNA promoters

    Fatih Ozsolak;Laura L. Poling;Zhengxin Wang;Hui Liu

  • Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF

    Rizwan Haq;Jonathan Shoag;Pedro Andreu-Perez;Satoru Yokoyama;Satoru Yokoyama

  • Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function

    Andrea Boni;Alexandria P. Cogdill;Ping Dang;Durga Udayakumar

  • Central Role of p53 in the Suntan Response and Pathologic Hyperpigmentation

    Rutao Cui;Hans R. Widlund;Erez Feige;Jennifer Y. Lin

  • MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

    Timothy J. Hemesath;E. Roydon Price;Clifford M Takemoto;Tina Badalian

  • BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma

    E.Elizabeth Patton;Hans R. Widlund;Jeffery L. Kutok;Kamden R. Kopani;Kamden R. Kopani

  • Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

    Sabine Venderbosch;Iris D Nagtegaal;Timothy S Maughan;Christopher G Smith

  • Malignant melanoma: genetics and therapeutics in the genomic era

    Lynda Chin;Levi A. Garraway;Levi A. Garraway;David E. Fisher;David E. Fisher

Frequent Co-Authors

Keith T. Flaherty
Keith T. Flaherty Harvard University
Levi A. Garraway
Levi A. Garraway Roche (United States)
Leonard I. Zon
Leonard I. Zon Harvard University
F. Stephen Hodi
F. Stephen Hodi Harvard University
Dennie T. Frederick
Dennie T. Frederick Broad Institute
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Ryan J. Sullivan
Ryan J. Sullivan Harvard University
Sridhar Ramaswamy
Sridhar Ramaswamy Harvard University
Arlene H. Sharpe
Arlene H. Sharpe Harvard University
Hensin Tsao
Hensin Tsao Harvard University

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