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Corine Bertolotto

Corine Bertolotto

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11585
World Ranking
13842
National Ranking
530

Overview

Corine Bertolotto is affiliated with Université Côte d'Azur in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broader categories, their work has a significant focus on Molecular Biology, Ophthalmology, Oncology, Immunology, and Cell Biology.

The recent scholarly contributions of Corine Bertolotto cover several dimensions of melanoma research and related therapies. Notable publications include:

  • Melanoma models for the next generation of therapies, 2021, Cancer Cell
  • Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease, 2021, Cell Death and Differentiation
  • The "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies", 2020, Theranostics
  • The complex relationship between MITF and the immune system: a Melanoma ImmunoTherapy (response) Factor?, 2020, Molecular Cancer
  • Prognostic Biomarkers in Uveal Melanoma: The Status Quo, Recent Advances and Future Directions, 2021, Cancers

Corine Bertolotto frequently publishes in these journals:

  • Cancers
  • Molecular Cancer
  • Cell Death and Differentiation
  • Theranostics
  • EMBO Molecular Medicine

Frequent collaborators include Robert Ballotti, Arnaud Martel, Sacha Nahon-Estève, Stéphanie Baillif, and Sandra Lassalle.

Their research topics predominantly cover:

  • Ocular Oncology and Treatments
  • Melanoma and MAPK Pathways
  • Cutaneous Melanoma Detection and Management
  • Immunotherapy and Immune Responses
  • Protein Degradation and Inhibitors
  • Genomics and Chromatin Dynamics
  • Ubiquitin and proteasome pathways

Best Publications

  • Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

    Issam Ben Sahra;Kathiane Laurent;Sandy Giuliano;Frédéric Larbret

  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  • Microphthalmia Gene Product as a Signal Transducer in cAMP-Induced Differentiation of Melanocytes

    Corine Bertolotto;Patricia Abbe;Timothy J. Hemesath;Karine Bille

  • Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia

    Corine Bertolotto;Roser Buscà;Patricia Abbe;Karine Bille

  • Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

    Yann Cheli;Mickael Ohanna;Robert Ballotti;Corine Bertolotto

  • Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

    Tomic T;Botton T;Botton T;Cerezo M;Cerezo M;Robert G;Robert G

  • Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation

    Roser Buscà;Corine Bertolotto;Jean-Paul Ortonne;Robert Ballotti

  • Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)

    Mickaël Ohanna;Sandy Giuliano;Caroline Bonet;Véronique Imbert

  • Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

    T Strub;S Giuliano;T Ye;C Bonet

  • Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny

    Y Cheli;Y Cheli;S Guiliano;S Guiliano;T Botton;T Botton;S Rocchi;S Rocchi

  • Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

    Michaël Cerezo;Michaël Cerezo;Abdelali Lehraiki;Abdelali Lehraiki;Antoine Millet;Florian Rouaud;Florian Rouaud

  • Glycogen Synthase Kinase 3β Is Activated by cAMP and Plays an Active Role in the Regulation of Melanogenesis

    Mehdi Khaled;Lionel Larribere;Karine Bille;Edith Aberdam

  • Involvement of microphthalmia in the inhibition of melanocyte lineage differentiation and of melanogenesis by agouti signal protein.

    E Aberdam;C Bertolotto;E V Sviderskaya;V de Thillot

  • Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

    Michaël Cerezo;Mélanie Tichet;Patricia Abbe;Mickaël Ohanna

  • Inhibition of the Mitogen-activated Protein Kinase Pathway Triggers B16 Melanoma Cell Differentiation

    Walter Englaro;Corine Bertolotto;Roser Buscà;Anne Brunet

  • Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product.

    C Bertolotto;K Bille;J P Ortonne;R Ballotti

  • GLI2-Mediated Melanoma Invasion and Metastasis

    Vasileia-Ismini Alexaki;Delphine Javelaud;Delphine Javelaud;Delphine Javelaud;Leon C. L. Van Kempen;Khalid S. Mohammad

  • Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

    Y Cheli;S Giuliano;S Giuliano;N Fenouille;N Fenouille;M Allegra;M Allegra

  • Protein Kinase C θ and ε Promote T-cell Survival by a Rsk-dependent Phosphorylation and Inactivation of BAD

    Corine Bertolotto;Laurence Maulon;Nathalie Filippa;Gottfried Baier

  • Hypoxia-inducible factor 1α is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells

    Roser Buscà;Edurne Berra;Cédric Gaggioli;Mehdi Khaled

Frequent Co-Authors

Robert Ballotti
Robert Ballotti Université Côte d'Azur
Jean-Paul Ortonne
Jean-Paul Ortonne Grenoble Alpes University
Brigitte Bressac-de Paillerets
Brigitte Bressac-de Paillerets Institut Gustave Roussy
Paul Hofman
Paul Hofman Grenoble Alpes University
Patrick Auberger
Patrick Auberger Grenoble Alpes University
Irwin Davidson
Irwin Davidson Institute of Genetics and Molecular and Cellular Biology
Marcel Deckert
Marcel Deckert Université Côte d'Azur
Jean-Ehrland Ricci
Jean-Ehrland Ricci Université Côte d'Azur
Alain Mauviel
Alain Mauviel Institute Curie
Caroline Robert
Caroline Robert University of Paris-Saclay

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