D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 9,299 110 World Ranking 12616 National Ranking 474

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Apoptosis

Corine Bertolotto spends much of her time researching Microphthalmia-associated transcription factor, Melanoma, Cancer research, Transcription factor and Melanocyte differentiation. She focuses mostly in the field of Microphthalmia-associated transcription factor, narrowing it down to matters related to Protein kinase A and, in some cases, E-box, Protein kinase B, GSK3B, PI3K/AKT/mTOR pathway and GSK-3. Her studies in Melanoma integrate themes in fields like Cell cycle, Chromatin immunoprecipitation, Metastasis and Matrigel.

Corine Bertolotto interconnects Cancer cell, Apoptosis, Internal medicine and Endocrinology in the investigation of issues within Cancer research. Her Transcription factor research is multidisciplinary, incorporating perspectives in Molecular biology, Regulation of gene expression, Mitosis and HIF1A. Her study looks at the intersection of Melanocyte differentiation and topics like Melanocyte with Pigment cell differentiation, Response element, Microphthalmia, IRF4 and Transcriptional regulation.

Her most cited work include:

  • Microphthalmia Gene Product as a Signal Transducer in cAMP-Induced Differentiation of Melanocytes (402 citations)
  • Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells (394 citations)
  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma (339 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Cancer research, Melanoma, Microphthalmia-associated transcription factor, Transcription factor and Cell biology. Her Cancer research research includes themes of Cancer cell, Apoptosis, Immunology, Signal transduction and Gene silencing. Her study explores the link between Apoptosis and topics such as Cell growth that cross with problems in Cell aging.

Her work in Melanoma tackles topics such as Endocrinology which are related to areas like Melanin. Corine Bertolotto has included themes like Regulation of gene expression, Germline mutation and Melanocyte in her Microphthalmia-associated transcription factor study. The Transcription factor study combines topics in areas such as Molecular biology, Gene expression and Microphthalmia.

She most often published in these fields:

  • Cancer research (81.25%)
  • Melanoma (81.25%)
  • Microphthalmia-associated transcription factor (51.56%)

What were the highlights of her more recent work (between 2017-2021)?

  • Melanoma (81.25%)
  • Cancer research (81.25%)
  • Microphthalmia-associated transcription factor (51.56%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Melanoma, Cancer research, Microphthalmia-associated transcription factor, Transcription factor and Cell culture. Her Melanoma study incorporates themes from Cancer cell, Targeted therapy, Metastasis, Epigenetics and Immunotherapy. Her study in Cancer research is interdisciplinary in nature, drawing from both Phenotype, Cell, Signal transduction and Cytotoxicity.

Her Microphthalmia-associated transcription factor study combines topics from a wide range of disciplines, such as V600E, Sphingolipid, Ceramide and Immune system. In her research, Chemokine and CXCL10 is intimately related to Gene silencing, which falls under the overarching field of Transcription factor. Her Cell culture research incorporates themes from Regulation of gene expression, Kojic acid, Epidermis and Hyperpigmentation.

Between 2017 and 2021, her most popular works were:

  • Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype (36 citations)
  • Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo (24 citations)
  • The "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies". (17 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Apoptosis

Corine Bertolotto mostly deals with Cancer research, Melanoma, Cell culture, Epigenetics and Regulation of gene expression. Her Cancer research research is multidisciplinary, relying on both Microphthalmia-associated transcription factor, Signal transduction, Ubiquitin ligase and ASAH1. Corine Bertolotto interconnects Sphingosine, Sphingosine-1-phosphate, V600E, Sphingolipid and Ceramide in the investigation of issues within Microphthalmia-associated transcription factor.

Her research in Signal transduction intersects with topics in Cell cycle, Transcription factor, E2F1 and Programmed cell death. Melanoma connects with themes related to Experimental pathology in her study. Her Epigenetics research integrates issues from Targeted therapy, Drug resistance, Cutaneous melanoma and Skin cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Microphthalmia Gene Product as a Signal Transducer in cAMP-Induced Differentiation of Melanocytes

Corine Bertolotto;Patricia Abbe;Timothy J. Hemesath;Karine Bille.
Journal of Cell Biology (1998)

589 Citations

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

Issam Ben Sahra;Kathiane Laurent;Sandy Giuliano;Frédéric Larbret.
Cancer Research (2010)

532 Citations

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub.
Nature (2011)

526 Citations

Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia

Corine Bertolotto;Roser Buscà;Patricia Abbe;Karine Bille.
Molecular and Cellular Biology (1998)

367 Citations

Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

Yann Cheli;Mickael Ohanna;Robert Ballotti;Corine Bertolotto.
Pigment Cell & Melanoma Research (2010)

351 Citations

Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation

Roser Buscà;Corine Bertolotto;Jean-Paul Ortonne;Robert Ballotti.
Journal of Biological Chemistry (1996)

326 Citations

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

Tomic T;Botton T;Botton T;Cerezo M;Cerezo M;Robert G;Robert G.
Cell Death and Disease (2011)

286 Citations

Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)

Mickaël Ohanna;Sandy Giuliano;Caroline Bonet;Véronique Imbert.
Genes & Development (2011)

262 Citations

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

T Strub;S Giuliano;T Ye;C Bonet.
Oncogene (2011)

252 Citations

Inhibition of the Mitogen-activated Protein Kinase Pathway Triggers B16 Melanoma Cell Differentiation

Walter Englaro;Corine Bertolotto;Roser Buscà;Anne Brunet.
Journal of Biological Chemistry (1998)

240 Citations

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