Corine Bertolotto spends much of her time researching Microphthalmia-associated transcription factor, Melanoma, Cancer research, Transcription factor and Melanocyte differentiation. She focuses mostly in the field of Microphthalmia-associated transcription factor, narrowing it down to matters related to Protein kinase A and, in some cases, E-box, Protein kinase B, GSK3B, PI3K/AKT/mTOR pathway and GSK-3. Her studies in Melanoma integrate themes in fields like Cell cycle, Chromatin immunoprecipitation, Metastasis and Matrigel.
Corine Bertolotto interconnects Cancer cell, Apoptosis, Internal medicine and Endocrinology in the investigation of issues within Cancer research. Her Transcription factor research is multidisciplinary, incorporating perspectives in Molecular biology, Regulation of gene expression, Mitosis and HIF1A. Her study looks at the intersection of Melanocyte differentiation and topics like Melanocyte with Pigment cell differentiation, Response element, Microphthalmia, IRF4 and Transcriptional regulation.
Her main research concerns Cancer research, Melanoma, Microphthalmia-associated transcription factor, Transcription factor and Cell biology. Her Cancer research research includes themes of Cancer cell, Apoptosis, Immunology, Signal transduction and Gene silencing. Her study explores the link between Apoptosis and topics such as Cell growth that cross with problems in Cell aging.
Her work in Melanoma tackles topics such as Endocrinology which are related to areas like Melanin. Corine Bertolotto has included themes like Regulation of gene expression, Germline mutation and Melanocyte in her Microphthalmia-associated transcription factor study. The Transcription factor study combines topics in areas such as Molecular biology, Gene expression and Microphthalmia.
Her primary scientific interests are in Melanoma, Cancer research, Microphthalmia-associated transcription factor, Transcription factor and Cell culture. Her Melanoma study incorporates themes from Cancer cell, Targeted therapy, Metastasis, Epigenetics and Immunotherapy. Her study in Cancer research is interdisciplinary in nature, drawing from both Phenotype, Cell, Signal transduction and Cytotoxicity.
Her Microphthalmia-associated transcription factor study combines topics from a wide range of disciplines, such as V600E, Sphingolipid, Ceramide and Immune system. In her research, Chemokine and CXCL10 is intimately related to Gene silencing, which falls under the overarching field of Transcription factor. Her Cell culture research incorporates themes from Regulation of gene expression, Kojic acid, Epidermis and Hyperpigmentation.
Corine Bertolotto mostly deals with Cancer research, Melanoma, Cell culture, Epigenetics and Regulation of gene expression. Her Cancer research research is multidisciplinary, relying on both Microphthalmia-associated transcription factor, Signal transduction, Ubiquitin ligase and ASAH1. Corine Bertolotto interconnects Sphingosine, Sphingosine-1-phosphate, V600E, Sphingolipid and Ceramide in the investigation of issues within Microphthalmia-associated transcription factor.
Her research in Signal transduction intersects with topics in Cell cycle, Transcription factor, E2F1 and Programmed cell death. Melanoma connects with themes related to Experimental pathology in her study. Her Epigenetics research integrates issues from Targeted therapy, Drug resistance, Cutaneous melanoma and Skin cancer.
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Microphthalmia Gene Product as a Signal Transducer in cAMP-Induced Differentiation of Melanocytes
Corine Bertolotto;Patricia Abbe;Timothy J. Hemesath;Karine Bille.
Journal of Cell Biology (1998)
Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells
Issam Ben Sahra;Kathiane Laurent;Sandy Giuliano;Frédéric Larbret.
Cancer Research (2010)
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub.
Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia
Corine Bertolotto;Roser Buscà;Patricia Abbe;Karine Bille.
Molecular and Cellular Biology (1998)
Fifteen‐year quest for microphthalmia‐associated transcription factor target genes
Yann Cheli;Mickael Ohanna;Robert Ballotti;Corine Bertolotto.
Pigment Cell & Melanoma Research (2010)
Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation
Roser Buscà;Corine Bertolotto;Jean-Paul Ortonne;Robert Ballotti.
Journal of Biological Chemistry (1996)
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
Tomic T;Botton T;Botton T;Cerezo M;Cerezo M;Robert G;Robert G.
Cell Death and Disease (2011)
Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)
Mickaël Ohanna;Sandy Giuliano;Caroline Bonet;Véronique Imbert.
Genes & Development (2011)
Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
T Strub;S Giuliano;T Ye;C Bonet.
Inhibition of the Mitogen-activated Protein Kinase Pathway Triggers B16 Melanoma Cell Differentiation
Walter Englaro;Corine Bertolotto;Roser Buscà;Anne Brunet.
Journal of Biological Chemistry (1998)
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