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Alain Mauviel

Alain Mauviel

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
18071
World Ranking
4862
National Ranking
134

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Alain Mauviel is affiliated with Institute Curie in France, focusing primarily on research within the fields of Biochemistry, Genetics, and Molecular Biology, with additional contributions in Medicine. Their work spans various subfields including Molecular Biology, Genetics, Endocrinology, Oncology, and Pathology and Forensic Medicine.

The scientist's research topics include:

  • Pancreatic and Hepatic Oncology Research
  • Hedgehog Signaling Pathway Studies
  • Escherichia coli research studies
  • Bacterial Genetics and Biotechnology
  • TGF-β signaling in diseases
  • Genetic factors in colorectal cancer
  • Chromatin Remodeling and Cancer

Alain Mauviel has published in several scientific venues, contributing to communications in these journals and platforms:

  • Communications Biology
  • Biochemical Journal
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Life Science Alliance

Selected recent papers by the scientist include:

  • "SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4," 2022, Communications Biology
  • "GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression," 2020, Biochemical Journal
  • "Large-scale pan-cancer analysis reveals broad prognostic association between TGF-β ligands, not Hedgehog, and GLI1/2 expression in tumors," 2020, Scientific Reports
  • "IpaA reveals distinct modes of vinculin activation during Shigella invasion and cell-matrix adhesion," 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • "IpaA reveals distinct modes of vinculin activation during Shigella invasion and cell-matrix adhesion," 2024, Life Science Alliance

Frequent collaborators who have coauthored multiple papers with Alain Mauviel include:

  • Delphine Javelaud
  • Véronique Marsaud
  • Hamed Khakzad
  • Mahamadou Konate
  • Daniel Aguilar

Alain Mauviel's publications and research have contributed to multiple thematic areas linking molecular signaling pathways such as TGF-β and Hedgehog signaling to oncogenic processes and bacterial biology, reflecting an interdisciplinary approach intersecting cancer research and microbiology.

Best Publications

  • Transforming Growth Factor-β Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation

    Franck Verrecchia;Alain Mauviel

  • Identification of Novel TGF-β/Smad Gene Targets in Dermal Fibroblasts using a Combined cDNA Microarray/Promoter Transactivation Approach

    Franck Verrecchia;Mon-Li Chu;Alain Mauviel

  • Transforming growth factor-beta and fibrosis.

    Franck Verrecchia;Alain Mauviel

  • TGF-β-induced SMAD signaling and gene regulation : consequences for extracellular matrix remodeling and wound healing

    Meinhard Schiller;Delphine Javelaud;Alain Mauviel

  • Cytokine regulation of metalloproteinase gene expression

    Alain Mauviel

  • Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

    Delphine Javelaud;Alain Mauviel

  • Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.

    Sylviane Dennler;Jocelyne André;Ismini Alexaki;Allen Li

  • An AP-1 Binding Sequence Is Essential for Regulation of the Human α2(I) Collagen (COL1A2) Promoter Activity by Transforming Growth Factor-β

    Kee Yang Chung;Akhilesh Agarwal;Jouni Uitto;Alain Mauviel

  • EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair.

    Eric E. Gabison;Thanh Hoang-Xuan;Alain Mauviel;Suzanne Menashi

  • Enhanced elastin and fibrillin gene expression in chronically photodamaged skin

    Eric F. Bernstein;Yue Qiu Chen;Katsuto Tamai;Kenneth J. Shepley

  • Transforming Growth Factor-β

    Alain Mauviel

  • Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling.

    Olivier Ferrigno;François Lallemand;Franck Verrecchia;Sébastien L'Hoste

  • Amelioration of Radiation-induced Fibrosis: INHIBITION OF TRANSFORMING GROWTH FACTOR-β SIGNALING BY HALOFUGINONE *

    Sandhya Xavier;Ester Piek;Makiko Fujii;Delphine Javelaud

  • Transforming growth factor β stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit articular chondrocytes

    F. Redini;P. Galera;A. Mauviel;G. Loyau

  • TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression.

    Franck Verrecchia;Alain Mauviel

  • TGF-β-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

    Khalid S. Mohammad;Delphine Javelaud;Delphine Javelaud;Pierrick G. J. Fournier;Maria Niewolna;Maria Niewolna

  • Mammalian transforming growth factor-βs: Smad signaling and physio-pathological roles

    Delphine Javelaud;Alain Mauviel

  • Cell-specific Induction of Distinct Oncogenes of the Jun Family Is Responsible for Differential Regulation of Collagenase Gene Expression by Transforming Growth Factor-β in Fibroblasts and Keratinocytes

    Alain Mauviel;Kee-Yang Chung;Akhilesh Agarwal;Katsuto Tamai

  • Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

    Delphine Javelaud;Khalid S. Mohammad;Christopher R. McKenna;Pierrick Fournier

  • Smad3/AP-1 interactions control transcriptional responses to TGF-β in a promoter-specific manner

    Franck Verrecchia;Laurence Vindevoghel;Robert J Lechleider;Jouni Uitto

Frequent Co-Authors

Jouni Uitto
Jouni Uitto Thomas Jefferson University
Veli-Matti Kähäri
Veli-Matti Kähäri Turku University Hospital
Anita B. Roberts
Anita B. Roberts National Institutes of Health
Renato V. Iozzo
Renato V. Iozzo Thomas Jefferson University
Lionel Larue
Lionel Larue University of Paris-Saclay
Louis Dubertret
Louis Dubertret University of Münster
Ulrich Rodeck
Ulrich Rodeck Thomas Jefferson University
Edward B. Leof
Edward B. Leof Mayo Clinic
Robert Ballotti
Robert Ballotti Université Côte d'Azur
Taina Pihlajaniemi
Taina Pihlajaniemi University of Oulu

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