2022 - Research.com Genetics and Molecular Biology in Sweden Leader Award
2016 - Fellow of the American Academy of Arts and Sciences
1999 - Member of Academia Europaea
Member of the European Molecular Biology Organization (EMBO)
His primary scientific interests are in Platelet-derived growth factor receptor, Cell biology, Growth factor, Platelet-derived growth factor and Signal transduction. The various areas that Carl-Henrik Heldin examines in his Platelet-derived growth factor receptor study include Molecular biology, Cancer research, Autophosphorylation and Cell culture. His work carried out in the field of Cell biology brings together such families of science as Transforming growth factor, beta 3, Biochemistry, Cell type and Chemotaxis.
His Growth factor research includes themes of Progenitor cell, Endocrinology and Autocrine signalling. His Platelet-derived growth factor research is multidisciplinary, incorporating elements of Epidermal growth factor, Gene expression, In situ hybridization, Immunology and Glioma. Carl-Henrik Heldin has researched Signal transduction in several fields, including Bone morphogenetic protein, Phosphorylation and Ectopic expression.
His primary areas of investigation include Cell biology, Platelet-derived growth factor receptor, Platelet-derived growth factor, Receptor and Growth factor. Cell biology is a component of his Signal transduction, SMAD, Transforming growth factor, Phosphorylation and Transforming growth factor beta studies. His SMAD research includes elements of R-SMAD, Transcription factor and Bone morphogenetic protein.
His Platelet-derived growth factor receptor research is multidisciplinary, incorporating perspectives in Molecular biology, Cancer research, Receptor tyrosine kinase and Endocrinology. Paracrine signalling is closely connected to Autocrine signalling in his research, which is encompassed under the umbrella topic of Platelet-derived growth factor. His Growth factor research incorporates themes from Cell culture, Epidermal growth factor, Cell growth, Chemotaxis and Platelet.
His primary areas of study are Cell biology, Cancer research, Transforming growth factor, Signal transduction and Platelet-derived growth factor receptor. His Cell biology study combines topics in areas such as Receptor and Ubiquitin ligase. His work deals with themes such as Cancer cell, Transcription factor, Autocrine signalling and Liver X receptor, which intersect with Transforming growth factor.
His study in Signal transduction is interdisciplinary in nature, drawing from both Cell surface receptor, Tissue homeostasis and Protein kinase A. A large part of his Platelet-derived growth factor receptor studies is devoted to Platelet-derived growth factor. His research in Transforming growth factor beta intersects with topics in TGF beta signaling pathway and Molecular biology.
Carl-Henrik Heldin focuses on Cancer research, Signal transduction, Cell biology, Transforming growth factor and Receptor. His studies deal with areas such as Cell migration, Immunology, Cytokine, Tumor progression and Transforming growth factor beta as well as Cancer research. His Signal transduction research focuses on Phosphorylation and how it connects with SUMO protein.
The concepts of his Cell biology study are interwoven with issues in Embryonic stem cell, Epidermal growth factor, Cellular differentiation, Internalization and Ubiquitin ligase. His work in Platelet-derived growth factor receptor, Cell surface receptor and Growth factor receptor is related to Receptor. Carl-Henrik Heldin studies Platelet-derived growth factor which is a part of Platelet-derived growth factor receptor.
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TGF-beta signalling from cell membrane to nucleus through SMAD proteins
Carl-Henrik Heldin;Kohei Miyazono;Peter ten Dijke.
Nature (1997)
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
Carl-Henrik Heldin;Bengt Westermark.
Physiological Reviews (1999)
Dimerization of cell surface receptors in signal transduction
Carl-Henrik Heldin.
Cell (1995)
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
Atsuhito Nakao;Mozhgan Afrakhte;Anita Morn;Takuya Nakayama.
Nature (1997)
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.
Michael D. Waterfield;Geoffrey T. Scrace;Nigel Whittle;Paul Stroobant.
Nature (1983)
High interstitial fluid pressure — an obstacle in cancer therapy
Carl-Henrik Heldin;Kristofer Rubin;Kristian Pietras;Arne Östman.
Nature Reviews Cancer (2004)
Non-Smad TGF-β signals
Aristidis Moustakas;Carl-Henrik Heldin.
Journal of Cell Science (2005)
Smad regulation in TGF-beta signal transduction.
Aristidis Moustakas;Serhiy Souchelnytskyi;Carl-Henrik Heldin.
Journal of Cell Science (2001)
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
Atsuhito Nakao;Takeshi Imamura;Takeshi Imamura;Serhiy Souchelnytskyi;Masahiro Kawabata.
The EMBO Journal (1997)
Specificity, diversity, and regulation in TGF-β superfamily signaling
Ester Piek;Carl-Henrik Heldin;Peter Ten Dijke.
The FASEB Journal (1999)
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