Lars Rönnstrand

What is he best known for?

The fields of study he is best known for:

• Gene
• Enzyme
• Cancer

Lars Rönnstrand focuses on Platelet-derived growth factor receptor, Cell biology, Molecular biology, Signal transduction and Autophosphorylation. His research in Platelet-derived growth factor receptor is mostly focused on Platelet-derived growth factor. In general Cell biology study, his work on Receptor tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Growth factor receptor often relates to the realm of Ataxia-telangiectasia, thereby connecting several areas of interest.

His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Transforming growth factor, Phosphorylation and White. His Signal transduction study typically links adjacent topics like Cancer research. His Autophosphorylation study combines topics in areas such as SH3 domain, GRB2 and Protein kinase C.

His most cited work include:

• SIGNAL TRANSDUCTION VIA PLATELET-DERIVED GROWTH FACTOR RECEPTORS (640 citations)
• Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A (447 citations)
• Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types (438 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Receptor tyrosine kinase, Phosphorylation, Cancer research and Signal transduction. His Cell biology study integrates concerns from other disciplines, such as Chemotaxis and Platelet-derived growth factor receptor. His Platelet-derived growth factor receptor research integrates issues from Molecular biology and Autophosphorylation.

His Receptor tyrosine kinase research includes themes of Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src, Protein tyrosine phosphatase and Tyrosine phosphorylation. The Phosphorylation study combines topics in areas such as Tyrosine, Kinase and Mutant. His Signal transduction research incorporates elements of Stem cell factor and Fms-Like Tyrosine Kinase 3.

He most often published in these fields:

• Cell biology (41.82%)
• Receptor tyrosine kinase (36.82%)
• Phosphorylation (31.82%)

What were the highlights of his more recent work (between 2015-2020)?

• Cancer research (29.09%)
• Cell biology (41.82%)
• Tyrosine kinase (20.00%)

In recent papers he was focusing on the following fields of study:

Cancer research, Cell biology, Tyrosine kinase, Myeloid leukemia and Receptor tyrosine kinase are his primary areas of study. In the field of Cell biology, his study on Phosphorylation, Signal transducing adaptor protein and Src like adaptor overlaps with subjects such as Cell and molecular biology. His Phosphorylation research is multidisciplinary, relying on both Signal transduction, Mutant and Kinase.

His research on Tyrosine kinase also deals with topics like

• Protein kinase B which is related to area like SH2 domain,
• Proto-oncogene tyrosine-protein kinase Src which intersects with area such as Microphthalmia-associated transcription factor, Melanoma, Molecular biology and Tyrosine phosphorylation. His Molecular biology research includes themes of ROR1, Platelet-derived growth factor receptor, JAK-STAT signaling pathway and Protein tyrosine phosphatase. His research in Receptor tyrosine kinase intersects with topics in Haematopoiesis, Fms-Like Tyrosine Kinase 3 and Ligand.

Between 2015 and 2020, his most popular works were:

• Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML (61 citations)
• FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications (23 citations)
• De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia (21 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Enzyme
• Cancer

His scientific interests lie mostly in Tyrosine kinase, Fms-Like Tyrosine Kinase 3, Cancer research, Receptor tyrosine kinase and Phosphorylation. His study explores the link between Tyrosine kinase and topics such as Proto-oncogene tyrosine-protein kinase Src that cross with problems in JAK-STAT signaling pathway, Protein tyrosine phosphatase, Platelet-derived growth factor receptor, ROR1 and Molecular biology. His Cancer research study integrates concerns from other disciplines, such as Leukemia, Ibrutinib and Neuroblastoma.

Receptor tyrosine kinase is a subfield of Cell biology that Lars Rönnstrand studies. His Autophosphorylation, Haematopoiesis and Flt3 ligand study, which is part of a larger body of work in Cell biology, is frequently linked to Basic science, bridging the gap between disciplines. His Phosphorylation study combines topics in areas such as Scaffold protein, Signal transduction and Kinase.