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Molecular Biology
Denmark
2026
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Genetics and Molecular Biology
Denmark
2024

D-Index & Metrics

Molecular Biology

D-Index
120
Citations
63813
World Ranking
258
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Denmark Leader Award
  • 2025 - Research.com Molecular Biology in Denmark Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Denmark Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Denmark Leader Award
  • 2023 - Research.com Molecular Biology in Denmark Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Denmark Leader Award
  • 2018 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jiri Lukas is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology alongside work in Oncology, Surgery, Plant Science, and Cell Biology.

The scientist's main research topics include:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • Chromosomal and Genetic Variations
  • DNA and Nucleic Acid Chemistry
  • Epigenetics and DNA Methylation
  • PARP inhibition in cancer therapy

Recent publications demonstrate a concentration on DNA replication and genome stability. Key papers include:

  • Equilibrium between nascent and parental MCM proteins protects replicating genomes, 2020, Nature
  • Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication, 2020, Cell Reports
  • Homology-directed repair protects the replicating genome from metabolic assaults, 2021, Developmental Cell
  • Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication, 2021, Genes
  • Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes, 2022, Nature Communications

They have collaborated frequently with several researchers, including Kumar Somyajit, Hana Polášek-Sedláčková, Maj-Britt Rask, Gijs Zonderland, and Julian Spies. This indicates ongoing partnerships in related research themes.

Publication venues reflect a presence in journals such as:

  • Nature
  • Cell Reports
  • Developmental Cell
  • Genes
  • Nature Communications

Jiri Lukas has been recognized by their peers through membership in prestigious organizations, including the Academia Europaea since 2018 and the European Molecular Biology Organization (EMBO).

Best Publications

  • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

    Jirina Bartkova;Zuzana Horejsí;Karen Koed;Alwin Krämer

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

    Véronique Baldin;Jiri Lukas;María Jesús Marcote;Michele Pagano

  • Chk1 and Chk2 kinases in checkpoint control and cancer.

    Jiri Bartek;Jiri Lukas

  • Human CtIP promotes DNA end resection

    Alessandro A. Sartori;Claudia Lukas;Julia Coates;Martin Mistrik

  • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.

    Jacob Falck;Niels Mailand;Randi G. Syljuåsen;Jiri Bartek

  • ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

    Ali Jazayeri;Jacob Falck;Claudia Lukas;Jiri Bartek

  • RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

    Niels Mailand;Simon Bekker-Jensen;Helene Faustrup;Fredrik Melander

  • Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

    Jiri Lukas;David Parry;Louise Aagaard;David J. Mann

  • RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

    Carsten Doil;Niels Mailand;Simon Bekker-Jensen;Patrice Menard

  • Rapid destruction of human Cdc25A in response to DNA damage.

    Niels Mailand;Jacob Falck;Claudia Lukas;Randi G. Syljuåsen

  • Checking on DNA damage in S phase

    Jiri Bartek;Claudia Lukas;Jiri Lukas

  • DNA damage checkpoints: from initiation to recovery or adaptation.

    Jiri Bartek;Jiri Lukas

  • ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Luis Ignacio Toledo;Matthias Altmeyer;Maj-Britt Rask;Claudia Lukas

  • More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

    Jiri Lukas;Claudia Lukas;Jiri Bartek

  • Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

    Yael Ziv;Dana Bielopolski;Yaron Galanty;Claudia Lukas

  • Mammalian G1- and S-phase checkpoints in response to DNA damage.

    Jiri Bartek;Jiri Lukas

  • Repression of p15INK4b expression by Myc through association with Miz-1.

    Peter Staller;Karen Peukert;Astrid Kiermaier;Joan Seoane

  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

    Simon Bekker-Jensen;Claudia Lukas;Risa Kitagawa;Fredrik Melander

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

Frequent Co-Authors

Jiri Bartek
Jiri Bartek Karolinska Institute
Jirina Bartkova
Jirina Bartkova Karolinska Institute
Claudia Lukas
Claudia Lukas University of Copenhagen
Jiri Bartek
Jiri Bartek Karolinska Institute
Niels Mailand
Niels Mailand University of Copenhagen
Simon Bekker-Jensen
Simon Bekker-Jensen University of Copenhagen
Claus Storgaard Sørensen
Claus Storgaard Sørensen University of Copenhagen
Matthias Altmeyer
Matthias Altmeyer University of Zurich
Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
Maxwell Sehested
Maxwell Sehested Rigshospitalet

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