Jirina Bartkova

Overview

Best Publications

• DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

  Jirina Bartkova;Zuzana Horejsí;Karen Koed;Alwin Krämer

  3213
  Citations

• Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

  Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  2280
  Citations

• Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

  Jiri Lukas;David Parry;Louise Aagaard;David J. Mann

  1206
  Citations

• 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

  Peter Bouwman;Amal Mahmoud Aly;Jose M. Escandell;Mark Pieterse

  1147
  Citations

• DNA damage signalling guards against activated oncogenes and tumour progression.

  J Bartek;J Bartkova;J Lukas

  730
  Citations

• p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

  Sigrun Ressler;Jirina Bartkova;Harald Niederegger;Jiri Bartek

  692
  Citations

• Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

  Claudia Lukas;Jacob Falck;Jirina Bartkova;Jiri Bartek

  660
  Citations

• Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

  Zdenek Skrott;Martin Mistrik;Klaus Kaae Andersen;Søren Friis

  655
  Citations

• REV7 counteracts DNA double-strand break resection and affects PARP inhibition

  Guotai Xu;J. Ross Chapman;Inger Brandsma;Jingsong Yuan

  586
  Citations

• 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

  Richard A. DiTullio;Tamara A. Mochan;Tamara A. Mochan;Monica Venere;Monica Venere;Jirina Bartkova

  550
  Citations

• The retinoblastoma protein pathway and the restriction point

  Jiri Bartek;Jirina Bartkova;Jiri Lukas

  549
  Citations

• A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer.

  Pia Vahteristo;Jirina Bartkova;Hannaleena Eerola;Kirsi Syrjäkoski

  544
  Citations

• Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint.

  J Lukas;J Bartkova;J Bartek

  483
  Citations

• Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

  J Lukas;J Bartkova;M Rohde;M Strauss

  481
  Citations

• Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

  Petra Hamerlik;Justin D. Lathia;Rikke Rasmussen;Qiulian Wu

  458
  Citations

• A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas.

  Anne Girling;Jirina Bartkova;Joy Burchell;Sandra Gendler

  415
  Citations

• The p16-cyclin D/Cdk4-pRb Pathway as a Functional Unit Frequently Altered in Melanoma Pathogenesis

  Jirina Bartkova;Jiri Lukas;Per Guldberg;Jan Alsner

  389
  Citations

• The Retinoblastoma Protein Pathway in Cell Cycle Control and Cancer

  Jiri Bartek;Jirina Bartkova;Jiri Lukas

  367
  Citations

• Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16ink4a

  Martin Kosar;Jirina Bartkova;Sona Hubackova;Zdenek Hodny

  360
  Citations

• Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage

  Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  284
  Citations