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Zbigniew Darzynkiewicz

Zbigniew Darzynkiewicz

D-Index & Metrics

Biology and Biochemistry

D-Index
122
Citations
58949
World Ranking
580
National Ranking
370

Research.com Recognitions

  • 2021 - Polish Academy of Science
  • 2010 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Zbigniew Darzynkiewicz is affiliated with the New York Medical College in the United States. Their research spans several domains within molecular biology, oncology, genetics, pharmacology, and cancer research. Their work notably involves cancer-related molecular pathways, DNA repair mechanisms, microRNA in disease regulation, chronic lymphocytic leukemia research, berberine and alkaloids research, thyroid cancer diagnosis and treatment, and estrogen and related hormone effects.

Their frequent publication venues include Cytometry Part A, where they have contributed 21 papers, as well as Cancers, Scientific Reports, Reproductive Sciences, and Hypertension.

Recent papers authored or co-authored by Zbigniew Darzynkiewicz include:

  • "Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate," 2020, Reproductive Sciences
  • "Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients," 2020, Scientific Reports
  • "Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells," 2023, Cancers
  • "MicroRNA-133a-Dependent Inhibition of Proximal Tubule Angiotensinogen by Renal TNF (Tumor Necrosis Factor)," 2020, Hypertension
  • "40 Years of My Venture with CYTOMETRY," 2020, Cytometry Part A

They have collaborated frequently with researchers such as Attila Tárnok, Xunbin Wei, Henning Ulrich, Hong Zhao, and Dorota Halicka.

Zbigniew Darzynkiewicz has been recognized by several academic bodies and awarded distinctions including:

  • Polish Academy of Science, 2021
  • Fellow of the Indian National Academy of Engineering (INAE), 2010

Best Publications

  • Features of apoptotic cells measured by flow cytometry

    Z. Darzynkiewicz;S. Bruno;G. Del Bino;W. Gorczyca

  • Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)

    Zbigniew Darzynkiewicz;Zbigniew Darzynkiewicz;Gloria Juan;Xun Li;Wojciech Gorczyca

  • Detection of DNA Strand Breaks in Individual Apoptotic Cells by the in Situ Terminal Deoxynucleotidyl Transferase and Nick Translation Assays

    Wojciech Gorczyca;Jianping Gong;Zbigniew Darzynkiewicz

  • Relation of mammalian sperm chromatin heterogeneity to fertility.

    D. P. Evenson;Z. Darzynkiewicz;M. R. Melamed

  • Current protocols in cytometry

    J. Paul Robinson;Zbigniew Darzynkiewicz;Robert Hoffman;John P. Nolan

  • A Selective Procedure for DNA Extraction from Apoptotic Cells Applicable for Gel Electrophoresis and Flow Cytometry

    Jianping Gong;F. Traganos;Z. Darzynkiewicz

  • Analysis of cell cycle by flow cytometry.

    Piotr Pozarowski;Zbigniew Darzynkiewicz

  • Presence of DNA Strand Breaks and Increased Sensitivity of DNA in Situ to Denaturation in Abnormal Human Sperm Cells: Analogy to Apoptosis of Somatic Cells

    Wojciech Gorczyca;Frank Traganos;Hanna Jesionowska;Zbigniew Darzynkiewicz

  • The Cell Cycle Related Differences in Susceptibility of HL-60 Cells to Apoptosis Induced by Various Antitumor Agents

    Wojciech Gorczyca;Jianping Gong;Barbara Ardelt;Frank Traganos

  • Apoptosis and beyond: cytometry in studies of programmed cell death.

    Donald Wlodkowic;William Telford;Joanna Skommer;Zbigniew Darzynkiewicz

  • Lymphocyte stimulation: a rapid multiparameter analysis.

    Z Darzynkiewicz;F Traganos;T Sharpless;M R Melamed

  • Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells.

    S. Bruno;Z. Darzynkiewicz

  • Assays of cell viability: discrimination of cells dying by apoptosis

    Zbigniew Darzynkiewicz;Xun Li;Jianping Gong

  • Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system.

    F Traganos;Z Darzynkiewicz;T Sharpless;M R Melamed

  • Induction of DNA strand breaks associated with apoptosis during treatment of leukemias.

    W Gorczyca;K Bigman;A Mittelman;T Ahmed

  • Cell cycle-specific effects of lovastatin.

    Marek Jakobisiak;Silvia Bruno;Janusz S. Skierski;Zbigniew Darzynkiewicz

  • Apoptosis in adult retinal ganglion cells after axotomy.

    Garcia-Valenzuela E;Gorczyca W;Darzynkiewicz Z;Sharma Sc

  • New cell cycle compartments identified by multiparameter flow cytometry

    Zbigniew Darzynkiewicz;Frank Traganos;Myron R. Melamed

  • Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2.

    Tze-chen Hsieh;Gloria Juan;Zbigniew Darzynkiewicz;Joseph M. Wu

  • DNA strand breaks occurring during apoptosis - their early insitu detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors.

    W Gorczyca;S Bruno;Rj Darzynkiewicz;Jp Gong

Frequent Co-Authors

Frank Traganos
Frank Traganos New York Medical College
Myron R. Melamed
Myron R. Melamed New York Medical College
Joseph M. Wu
Joseph M. Wu New York Medical College
Tze-chen Hsieh
Tze-chen Hsieh New York Medical College
Donald P. Evenson
Donald P. Evenson University of South Dakota
Marek Kimmel
Marek Kimmel Rice University
Nils R. Ringertz
Nils R. Ringertz Karolinska Institute
Mikhail V. Blagosklonny
Mikhail V. Blagosklonny Roswell Park Cancer Institute
Michael Andreeff
Michael Andreeff The University of Texas MD Anderson Cancer Center
Bayard D. Clarkson
Bayard D. Clarkson Memorial Sloan Kettering Cancer Center

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