D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 91 Citations 26,135 326 World Ranking 5587 National Ranking 3116

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Internal medicine
  • Gene

Bayard D. Clarkson mostly deals with Internal medicine, Gastroenterology, Immunology, Leukemia and Tyrosine kinase. His Internal medicine study incorporates themes from Endocrinology, Surgery and Oncology. His Gastroenterology study integrates concerns from other disciplines, such as Platelet, Mortality rate, Acute Undifferentiated Leukemia and Toxicity.

The various areas that Bayard D. Clarkson examines in his Immunology study include Incidence, Absolute neutrophil count and Granulocyte colony-stimulating factor. His biological study spans a wide range of topics, including Regimen, Clinical trial and Cytogenetics. He combines subjects such as Cancer research, Proto-oncogene tyrosine-protein kinase Src and Imatinib mesylate with his study of Tyrosine kinase.

His most cited work include:

  • Structural mechanism for STI-571 inhibition of abelson tyrosine kinase (1571 citations)
  • Prognostic discrimination in "good-risk" chronic granulocytic leukemia (883 citations)
  • Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium (850 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Internal medicine, Immunology, Leukemia, Bone marrow and Molecular biology. The study incorporates disciplines such as Gastroenterology, Surgery and Oncology in addition to Internal medicine. His Gastroenterology research incorporates elements of Mucositis and Neutropenia.

His Immunology study combines topics from a wide range of disciplines, such as Progenitor cell, Haematopoiesis and In vitro. His research investigates the connection with Leukemia and areas like Cancer research which intersect with concerns in Tyrosine kinase and ABL. His Molecular biology research focuses on subjects like Cell culture, which are linked to Cell.

He most often published in these fields:

  • Internal medicine (33.18%)
  • Immunology (24.07%)
  • Leukemia (24.30%)

What were the highlights of his more recent work (between 1995-2017)?

  • Cancer research (17.29%)
  • ABL (10.75%)
  • Tyrosine kinase (8.64%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, ABL, Tyrosine kinase, Imatinib mesylate and Cell biology. His Cancer research research is multidisciplinary, incorporating elements of Leukemia, Signal transduction and Philadelphia chromosome. The various areas that Bayard D. Clarkson examines in his ABL study include Molecular biology, breakpoint cluster region and Kinase.

His Tyrosine kinase research includes themes of Phosphorylation and Tyrosine phosphorylation. His work deals with themes such as Src family kinase and Pathology, which intersect with Imatinib mesylate. His research in Progenitor cell intersects with topics in CD34 and Immunology.

Between 1995 and 2017, his most popular works were:

  • Structural mechanism for STI-571 inhibition of abelson tyrosine kinase (1571 citations)
  • Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571) (803 citations)
  • Structural basis for the autoinhibition of c-Abl tyrosine kinase (669 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Internal medicine
  • Gene

Tyrosine kinase, ABL, Cancer research, Cell biology and Proto-oncogene tyrosine-protein kinase Src are his primary areas of study. His Tyrosine kinase research is multidisciplinary, relying on both Molecular biology and Tyrosine phosphorylation. His biological study spans a wide range of topics, including breakpoint cluster region and Kinase, Protein kinase A.

The Cancer research study combines topics in areas such as Chronic myelogenous leukemia, Leukemia and Signal transduction. In his study, which falls under the umbrella issue of Leukemia, Myelogenous, Stem cell, Immunology, Myeloid and Cellular differentiation is strongly linked to Philadelphia chromosome. His research is interdisciplinary, bridging the disciplines of Biochemistry and Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

Thomas Schindler;William Bornmann;Patricia Pellicena;W. Todd Miller.
Science (2000)

2286 Citations

Prognostic discrimination in "good-risk" chronic granulocytic leukemia

JE Sokal;EB Cox;M Baccarani;S Tura.
Blood (1984)

1398 Citations

Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium

J.L. Gabrilove;J.L. Gabrilove;A. Jakubowski;A. Jakubowski;H. Scher;H. Scher;C. Sternberg;C. Sternberg.
The New England Journal of Medicine (1988)

1345 Citations

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Bhushan Nagar;William G Bornmann;Patricia Pellicena;Thomas Schindler.
Cancer Research (2001)

1176 Citations

Structural basis for the autoinhibition of c-Abl tyrosine kinase

Bhushan Nagar;Oliver Hantschel;Matthew A. Young;Klaus Scheffzek.
Cell (2003)

889 Citations

On the Use of Cause-Specific Failure and Conditional Failure Probabilities: Examples from Clinical Oncology Data

Jeffrey J. Gaynor;Erick J. Feuer;Claire C. Tan;Danny H. Wu.
Journal of the American Statistical Association (1993)

696 Citations

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Sizhi Paul Gao;Kevin G. Mark;Kenneth Leslie;William Pao.
Journal of Clinical Investigation (2007)

667 Citations

Control of proliferation in animal cells

Bayard Clarkson;Renato Baserga.
(1974)

587 Citations

Identification of human B and T lymphocytes by scanning electron microscopy.

A. Polliack;N. Lampen;B. D. Clarkson;E. De Harven.
Journal of Experimental Medicine (1973)

448 Citations

p62dok: A Constitutively Tyrosine-Phosphorylated, GAP-Associated Protein in Chronic Myelogenous Leukemia Progenitor Cells

Nick Carpino;Nick Carpino;David Wisniewski;Annabel Strife;Daniel Marshak.
Cell (1997)

434 Citations

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