2026 John Kuriyan: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	119	264	243	154	141	315	64096

Research.com Recognitions

2018 - Member of the National Academy of Medicine (NAM)
2015 - Fellow of the Royal Society, United Kingdom
2008 - Fellow of the American Academy of Arts and Sciences
2005 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for his critical role in revealing the structural mechanisms underlying processivity in DNA replication and the regulation of tyrosine kinases and their interacting target proteins.
2001 - Member of the National Academy of Sciences

Overview

John Kuriyan is affiliated with Vanderbilt University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a significant focus on molecular biology and genetics. The scientist's work also extends into subfields such as immunology, radiology, nuclear medicine and imaging, and materials chemistry.

The main topics of their research include:

Protein kinase regulation and GTPase signaling
Monoclonal and polyclonal antibodies research
Chronic lymphocytic leukemia research
Protein structure and dynamics
Enzyme structure and function
RNA and protein synthesis mechanisms
Ubiquitin and proteasome pathways

John Kuriyan has published extensively in several academic venues. The most frequent publication venues include:

bioRxiv (Cold Spring Harbor Laboratory)
eLife
Proceedings of the National Academy of Sciences
Protein Science
Science Signaling

Some recent papers authored or co-authored by Kuriyan are:

"Structural basis and regulation of the reductive stress response," 2021, published in Cell
"CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks," 2020, published in eLife
"A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane," 2022, published in Proceedings of the National Academy of Sciences
"Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation," 2020, published in eLife
"Structural basis for dimerization quality control," 2020, published in Nature

Frequent co-authors collaborating with Kuriyan include:

Jay T. Groves
Christine L. Gee
Serena Muratcioğlu
Timothy J. Eisen
Subu Subramanian

Throughout their career, John Kuriyan has received several recognitions and awards, including:

Member of the National Academy of Medicine (2018)
Fellow of the Royal Society, United Kingdom (2015)
Fellow of the American Academy of Arts and Sciences (2008)
Richard Lounsbery Award from the National Academy of Sciences and the French Academy of Sciences (2005) for revealing structural mechanisms underlying DNA replication processivity and regulation of tyrosine kinases and their interacting target proteins
Member of the National Academy of Sciences (2001)

Best Publications

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

Thomas Schindler;William Bornmann;Patricia Pellicena;W. Todd Miller

2431
Citations
The Conformational Plasticity of Protein Kinases

Morgan Huse;John Kuriyan;John Kuriyan

2163
Citations
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

Neil P. Shah;John M. Nicoll;Bhushan Nagar;Mercedes E. Gorre

2068
Citations
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor

Xuewu Zhang;Jodi Gureasko;Kui Shen;Philip A. Cole

1881
Citations
Crystal structure of the Src family tyrosine kinase Hck

Frank Sicheri;Ismail Moarefi;Ismail Moarefi;John Kuriyan;John Kuriyan

1527
Citations
Molecular dynamics and protein function

M. Karplus;J. Kuriyan

1335
Citations
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Bhushan Nagar;William G. Bornmann;Patricia Pellicena;Thomas Schindler

1261
Citations
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

Talluru S.R. Krishna;Xiang-Peng Kong;Sonja Gary;Peter M. Burgers

1137
Citations
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.

Jonathan Goldberg;Hsien Bin Huang;Young Guen Kwon;Paul Greengard

1127
Citations
Structural basis for the autoinhibition of c-Abl tyrosine kinase

Bhushan Nagar;Oliver Hantschel;Matthew A. Young;Klaus Scheffzek

1052
Citations
Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.

Elena Conti;Marc Uy;Marc Uy;Lore Leighton;Lore Leighton;Günter Blobel;Günter Blobel

1013
Citations
The structural basis of the activation of Ras by Sos

P.A Boriack-Sjodin;S.M Margarit;D Bar-Sagi;J. Kuriyan

1010
Citations
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms

Gabriel Waksman;Steven E. Shoelson;Nalin Pant;David Cowburn

986
Citations
Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

Jacqueline M Gulbis;Zvi Kelman;Jerard Hurwitz;Mike O'Donnell;Mike O'Donnell

978
Citations
Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

Xiang-Peng Kong;Rene Onrust;Mike O'Donnell;John Kuriyan;John Kuriyan

973
Citations
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.

Xiaomin Chen;Uwe Vinkemeier;Yanxiang Zhao;David Jeruzalmi

940
Citations
CRYSTAL-STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES

Gabriel Waksman;Dorothea Kominos;Scott C. Robertson;Scott C. Robertson;Nalin Pant

905
Citations
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

Catherine C. Smith;Qi Wang;Chen Shan Chin;Sara Salerno

840
Citations
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

I Moarefi;M LaFevre-Bernt;F Sicheri;M Huse

807
Citations
Modular peptide recognition domains in eukaryotic signaling.

John Kuriyan;David Cowburn

732
Citations

Frequent Co-Authors

Mike O'Donnell Rockefeller University

Jay T. Groves University of California, Berkeley

David E. Wemmer University of California, Berkeley

Arthur Weiss University of California, San Francisco

Holger Sondermann Kiel University

Howard Schulman Stanford University

Dafna Bar-Sagi New York University

Evan R. Williams University of California, Berkeley

Martin Karplus Harvard University

David E. Shaw D. E. Shaw Research

External Links

Wikipedia of John Kuriyan Personal website of John Kuriyan

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