What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Phosphorylation
The scientist’s investigation covers issues in Cell biology, Cancer research, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Src family kinase.
His Cell biology research incorporates themes from Molecular biology, Biochemistry and Kidney.
Many of his research projects under Cancer research are closely connected to STAT5B with STAT5B, tying the diverse disciplines of science together.
His Tyrosine kinase research includes themes of Chronic myelogenous leukemia and Kinase.
His Proto-oncogene tyrosine-protein kinase Src study combines topics in areas such as Cyclin-dependent kinase 9 and Mitogen-activated protein kinase kinase.
His study looks at the relationship between SH2 domain and fields such as Kinase activity, as well as how they intersect with chemical problems.
His most cited work include:
- A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor. (211 citations)
- Transformation of Myeloid Leukemia Cells to Cytokine Independence by Bcr-Abl Is Suppressed by Kinase-defective Hck (110 citations)
- Constitutive Activation of Stat5b Contributes to Carcinogenesis in Vivo (104 citations)
What are the main themes of his work throughout his whole career to date?
Thomas E. Smithgall focuses on Cell biology, Proto-oncogene tyrosine-protein kinase Src, Kinase activity, Kinase and SH3 domain.
His Proto-oncogene tyrosine-protein kinase Src study incorporates themes from Tyrosine kinase and Focal adhesion.
His Tyrosine kinase study deals with Cancer research intersecting with Cell growth.
His Kinase activity study integrates concerns from other disciplines, such as Molecular biology, Cellular differentiation and Protein kinase domain.
His studies in Kinase integrate themes in fields like Cell culture, Viral replication, Phosphorylation and Virology.
SH3 domain is a subfield of Biochemistry that Thomas E. Smithgall studies.
He most often published in these fields:
- Cell biology (48.73%)
- Proto-oncogene tyrosine-protein kinase Src (34.18%)
- Kinase activity (31.01%)
What were the highlights of his more recent work (between 2016-2020)?
- Cell biology (48.73%)
- Tyrosine kinase (26.58%)
- Kinase (29.75%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Tyrosine kinase, Kinase, Src family kinase and Virology.
His Cell biology research focuses on Proto-oncogene tyrosine-protein kinase Src in particular.
His research in Tyrosine kinase intersects with topics in Myeloid, Protein kinase domain and Kinase activity.
His Kinase activity research is multidisciplinary, incorporating perspectives in Receptor tyrosine kinase and Cell growth.
As a part of the same scientific study, Thomas E. Smithgall usually deals with the Kinase, concentrating on Cancer research and frequently concerns with Flt3 itd, Inhibitor resistance, Src family, Programmed cell death and Ubiquitin ligase.
His work in Src family kinase addresses subjects such as SH3 domain, which are connected to disciplines such as Transformation, Enzyme and Transferase.
Between 2016 and 2020, his most popular works were:
- HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. (47 citations)
- Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1 (31 citations)
- Pharmacologic HIV-1 Nef blockade promotes CD8 T cell–mediated elimination of latently HIV-1–infected cells in vitro (17 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Phosphorylation
Thomas E. Smithgall mainly focuses on Cell biology, Tyrosine kinase, Src family kinase, Kinase and Kinase activity.
Thomas E. Smithgall studies Cell biology, focusing on Signal transducing adaptor protein in particular.
His study of SH2 domain is a part of Tyrosine kinase.
The Kinase study combines topics in areas such as Leukemia and Syk.
Thomas E. Smithgall has researched Kinase activity in several fields, including Fms-Like Tyrosine Kinase 3, Cell growth, Proto-Oncogene Proteins c-fes, Molecular biology and Myeloid leukemia.
In his research, Telomere-binding protein, Mitosis, Chromatin, Gene and Phosphorylation is intimately related to Cancer research, which falls under the overarching field of Proto-Oncogene Proteins c-hck.
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