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Thomas E. Smithgall

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
12222
World Ranking
9838
National Ranking
4310

Thomas E. Smithgall publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Thomas E. Smithgall sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 237 publications — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Thomas E. Smithgall D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Thomas E. Smithgall sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Thomas E. Smithgall is affiliated with the University of Pittsburgh in the United States and focuses on research within the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work spreads across several subfields including Molecular Biology, Virology, Infectious Diseases, Hematology, and Immunology.

Their research explores topics such as HIV Research and Treatment, HIV/AIDS drug development and treatment, Protein Kinase Regulation and GTPase Signaling, HIV/AIDS Research and Interventions, Chronic Myeloid Leukemia Treatments, Cytokine Signaling Pathways and Interactions, and Ubiquitin and proteasome pathways.

Recent publications by Smithgall include:

  • "Behavioural immune landscapes of inflammation" (2022), published in Nature
  • "Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes" (2020), published in the Journal of Biological Chemistry
  • "Nef homodimers down-regulate SERINC5 by AP-2-mediated endocytosis to promote HIV-1 infectivity" (2020), published in the Journal of Biological Chemistry
  • "PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication" (2024), published in Cell chemical biology
  • "Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases" (2023), published in Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Smithgall include John J. Alvarado, Sherry T. Shu, Haibin Shi, Giancarlo Gonzalez-Areizaga, and Thomas E. Wales.

Their work appears prominently in several publication venues, including:

  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Scientific Reports
  • Nature

Best Publications

  • Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells

    R Garcia;CL Yu;A Hudnall;R Catlett

  • A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor.

    Satish C. Nair;Eric J. Toran;Ronald A. Rimerman;Scott Hjermstad

  • Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

    Gabriela Molina;Andreas Vogt;Ahmet Bakan;Weixiang Dai

  • Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.

    Judong Lee;Ee Wern Su;Chen Zhu;Sarah Hainline

  • The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells

    Agata Klejman;Steven J. Schreiner;Malgorzata Nieborowska‐Skorska;Artur Slupianek

  • SH3-mediated Hck Tyrosine Kinase Activation and Fibroblast Transformation by the Nef Protein of HIV-1

    Scott D. Briggs;Mark Sharkey;Mario Stevenson;Thomas E. Smithgall

  • Activation of Stat3 in v-Src Transformed Fibroblasts Requires Cooperation of Jak1 Kinase Activity

    Yi Zhang;James Turkson;Christin Carter-Su;Thomas Smithgall

  • Src Kinases Mediate STAT Growth Pathways in Squamous Cell Carcinoma of the Head and Neck

    Sichuan Xi;Qing Zhang;Kevin F. Dyer;Edwina C. Lerner

  • Structure and dynamic regulation of Src-family kinases.

    J. R. Engen;T. E. Wales;J. M. Hochrein;M. A. Meyn

  • Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA.

    Alice G. Bukrinskaya;Alice G. Bukrinskaya;Anuja Ghorpade;Nina K. Heinzinger;Nina K. Heinzinger;Thomas E. Smithgall

  • A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter

    Rosalba Perrone;Matteo Nadai;Ilaria Frasson;Jerrod A. Poe

  • SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells.

    Qing Zhang;Sufi M. Thomas;Sichuan Xi;Thomas E. Smithgall

  • Control of myeloid differentiation and survival by Stats.

    Thomas E Smithgall;Scott D Briggs;Steven Schreiner;Edwina C Lerner

  • Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.

    Steven J. Schreiner;Anthony P. Schiavone;Thomas E. Smithgall

  • Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation

    Qing Zhang;Sufi M. Thomas;Vivian Wai Yan Lui;Sichuan Xi

  • Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.

    Shanhai Xie;Yan Wang;Jiaxin Liu;Tong Sun

  • HIV-1 Nef Selectively Activates Src Family Kinases Hck, Lyn, and c-Src through Direct SH3 Domain Interaction

    Ronald P. Trible;Lori Emert-Sedlak;Thomas E. Smithgall

  • Src Family Kinases Phosphorylate the Bcr-Abl SH3-SH2 Region and Modulate Bcr-Abl Transforming Activity

    Malcolm A. Meyn;Matthew B. Wilson;Fadi A. Abdi;Nathalie Fahey

  • Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons.

    T E Smithgall;R G Harvey;T M Penning

  • Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

    Matthew B Wilson;Steven J Schreiner;Hyun-Jung Choi;Joanne Kamens

Frequent Co-Authors

John R. Engen
John R. Engen Northeastern University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Trevor M. Penning
Trevor M. Penning University of Pennsylvania
Billy W. Day
Billy W. Day University of Pittsburgh
Mathias Lösche
Mathias Lösche Carnegie Mellon University
Jennifer R. Grandis
Jennifer R. Grandis University of California, San Francisco
Robert I. Glazer
Robert I. Glazer Georgetown University Medical Center
Ronald G. Harvey
Ronald G. Harvey University of Chicago
Mario Stevenson
Mario Stevenson University of Miami
Giorgio Palù
Giorgio Palù University of Padua

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Related Online Degrees & Career Pathways

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Best Scientists Citing Thomas E. Smithgall

Trevor M. Penning

Trevor M. Penning

University of Pennsylvania

Publications: 75

Jennifer R. Grandis

Jennifer R. Grandis

University of California, San Francisco

Publications: 63

John R. Engen

John R. Engen

Northeastern University

Publications: 41

Richard Jove

Richard Jove

Nova Southeastern University

Publications: 39

Peter A. Greer

Peter A. Greer

Queen's University

Publications: 37

Paul Jolicoeur

Paul Jolicoeur

University of Montreal

Publications: 28

Gautam Sethi

Gautam Sethi

National University of Singapore

Publications: 23

Jorge E. Cortes

Jorge E. Cortes

Augusta University

Publications: 22

Kwang Seok Ahn

Kwang Seok Ahn

Kyung Hee University

Publications: 21

Hagop M. Kantarjian

Hagop M. Kantarjian

The University of Texas MD Anderson Cancer Center

Publications: 21

John C. Guatelli

John C. Guatelli

University of California, San Diego

Publications: 19

Hua Yu

Hua Yu

City Of Hope National Medical Center

Publications: 18

Ronald G. Harvey

Ronald G. Harvey

University of Chicago

Publications: 18

Yoel Sadovsky

Yoel Sadovsky

University of Pittsburgh

Publications: 18

Stefan Knapp

Stefan Knapp

Goethe University Frankfurt

Publications: 17

Carolyn B. Coyne

Carolyn B. Coyne

Duke University

Publications: 17

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