World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
18808
World Ranking
8116
National Ranking
3673

Chemistry

D-Index
67
Citations
18640
World Ranking
6813
National Ranking
2043

John R. Engen publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where John R. Engen sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 250 publications — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

John R. Engen D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John R. Engen sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 67 D-Index — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

John R. Engen is affiliated with Northeastern University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus also on Medicine. The subfields of their work include Molecular Biology, Spectroscopy, Oncology, Genetics, and Cell Biology.

The main topics that Engen has explored comprise Mass Spectrometry Techniques and Applications, Protein Structure and Dynamics, Analytical Chemistry and Chromatography, Ubiquitin and proteasome pathways, Enzyme Structure and Function, Chronic Lymphocytic Leukemia Research, and Chronic Myeloid Leukemia Treatments.

Among the frequent co-authors collaborating with Engen are Thomas E. Wales, Loren D. Walensky, Daniele Peterle, Roxana E. Iacob, and Amy H. Andreotti.

Engen's publications appear repeatedly in several scientific journals and preprint servers. Frequent venues include bioRxiv (Cold Spring Harbor Laboratory), eLife, Journal of Biological Chemistry, Nature Communications, and Journal of Molecular Biology.

Their recent papers include:

  • Developments in Hydrogen/Deuterium Exchange Mass Spectrometry, 2020, Analytical Chemistry
  • Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems, 2021, Chemical Reviews
  • Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism, 2020, Scientific Reports
  • Structural mechanism of a drug-binding process involving a large conformational change of the protein target, 2023, Nature Communications
  • Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase, 2021, Molecular Cell

Best Publications

  • Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

    Wenjun Zhou;Dalia Ercan;Liang Chen;Cai-Hong Yun

  • Hydrogen exchange mass spectrometry for the analysis of protein dynamics.

    Thomas E. Wales;John R. Engen

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

    Jianming Zhang;Francisco J. Adrián;Wolfgang Jahnke;Sandra W. Cowan-Jacob

  • Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

    Steven A. Berkowitz;John R. Engen;Jeffrey R. Mazzeo;Graham B. Jones

  • Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

    Damian Houde;Damian Houde;Yucai Peng;Steven A. Berkowitz;John R. Engen

  • Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.

    John R. Engen

  • High-speed and high-resolution UPLC separation at zero degrees Celsius.

    Thomas E. Wales;Keith E. Fadgen;Geoff C. Gerhardt;John R. Engen

  • The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

    Damian Houde;Damian Houde;Steven A. Berkowitz;John R. Engen

  • Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor†

    Sang Min Lim;Kenneth D. Westover;Scott B. Ficarro;Rane A. Harrison

  • Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

    Yuan Shi;Xiang Chen;Suzanne Elsasser;Bradley B. Stocks

  • Semi-automated data processing of hydrogen exchange mass spectra using HX-Express

    David D. Weis;John R. Engen;Ignatius J. Kass

  • Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

    Wenyu Yu;Emma J. Chory;Emma J. Chory;Amy K. Wernimont;Wolfram Tempel

  • Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding

    Edward C. Twomey;Zhejian Ji;Thomas E. Wales;Nicholas O. Bodnar

  • Force Interacts with Macromolecular Structure in Activation of TGF-β

    Xianchi Dong;Bo Zhao;Roxana E. Iacob;Jianghai Zhu

  • Investigating protein structure and dynamics by hydrogen exchange MS.

    John R. Engen;David L. Smith

  • Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems.

    Ellie I James;Taylor A Murphree;Clint Vorauer;John R Engen

  • Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice.

    Rida Mourtada;Rida Mourtada;Henry D. Herce;Daniel J. Yin;Jamie A. Moroco

  • Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry.

    Damian Houde;Joseph Arndt;Wayne Domeier;Steven Berkowitz

  • Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis.

    David D. Weis;Thomas E. Wales;John R. Engen;Matthew Hotchko

  • FOCUS :H YDROGEN EXCHANGE AND COVALENT MODIFICATION Identification and Characterization of EX1 Kinetics in H/D Exchange Mass Spectrometry by Peak Width Analysis

    David D. Weis;Thomas E. Wales;John R. Engen;Matthew Hotchko

Frequent Co-Authors

Thomas E. Smithgall
Thomas E. Smithgall University of Pittsburgh
Loren D. Walensky
Loren D. Walensky Harvard University
Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Nathanael S. Gray
Nathanael S. Gray Stanford University
Jarrod A. Marto
Jarrod A. Marto Harvard University
Scott B. Ficarro
Scott B. Ficarro Harvard University
Stephen C. Blacklow
Stephen C. Blacklow Harvard University
Alexandros Makriyannis
Alexandros Makriyannis Northeastern University
Sushil K. Satija
Sushil K. Satija National Institute of Standards and Technology
Kevin M. Haigis
Kevin M. Haigis Harvard University

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