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Chemistry

D-Index
63
Citations
12986
World Ranking
8502
National Ranking
215

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Canada Academy of Science

Overview

Lars Konermann is affiliated with the University of Western Ontario in Canada and has contributed extensively to research in chemistry and related fields. Their scientific output spans a variety of topics predominantly centered on mass spectrometry techniques and applications, analytical chemistry, and protein structure and dynamics.

The primary fields of study represented in Konermann's research include:

  • Chemistry
  • Biochemistry, Genetics and Molecular Biology
  • Engineering

They explore several specialized subfields, among which are:

  • Spectroscopy
  • Molecular Biology
  • Electrical and Electronic Engineering
  • Biomedical Engineering
  • Cell Biology

Key research topics covered in their work include:

  • Mass Spectrometry Techniques and Applications
  • Analytical Chemistry and Chromatography
  • Electrohydrodynamics and Fluid Dynamics
  • Protein Structure and Dynamics
  • Microfluidic and Capillary Electrophoresis Applications
  • Hemoglobin structure and function
  • Enzyme Structure and Function

Konermann's publications appear frequently in several scientific journals, notably:

  • Analytical Chemistry
  • The Journal of Physical Chemistry B
  • Journal of the American Society for Mass Spectrometry
  • Journal of the American Chemical Society
  • International Journal of Molecular Sciences

Notable recent papers authored or coauthored by Konermann include:

  • "On the Chemistry of Aqueous Ammonium Acetate Droplets during Native Electrospray Ionization Mass Spectrometry," 2023, Analytical Chemistry
  • "Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered," 2021, International Journal of Molecular Sciences
  • "Formation of Gaseous Proteins via the Ion Evaporation Model (IEM) in Electrospray Mass Spectrometry," 2020, Analytical Chemistry
  • "Analysis of Temperature-Dependent H/D Exchange Mass Spectrometry Experiments," 2020, Analytical Chemistry
  • "Mobile Protons Limit the Stability of Salt Bridges in the Gas Phase: Implications for the Structures of Electrosprayed Protein Ions," 2021, The Journal of Physical Chemistry B

Frequent collaborators in Konermann's research include:

  • Pablo M. Scrosati
  • Elnaz Aliyari
  • Victor Yin
  • Yousef Haidar
  • Nastaran N. Tajoddin

Konermann received the Fellowship of the Royal Society of Canada in 2018, recognized by the Academy of Science.

Best Publications

  • Hydrogen Exchange Mass Spectrometry for Studying Protein Structure and Dynamics

    Lars Konermann;Jingxi Pan;Yu-Hong Liu

  • Unraveling the Mechanism of Electrospray Ionization

    Lars Konermann;Elias Ahadi;Antony D. Rodriguez;Siavash Vahidi

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function

    Wael M. Rabeh;Florian Bossard;Haijin Xu;Tsukasa Okiyoneda

  • Acid-Induced Unfolding of Cytochrome c at Different Methanol Concentrations: Electrospray Ionization Mass Spectrometry Specifically Monitors Changes in the Tertiary Structure†

    Lars Konermann;D. J. Douglas

  • Addressing a Common Misconception: Ammonium Acetate as Neutral pH “Buffer” for Native Electrospray Mass Spectrometry

    Lars Konermann

  • Unfolding of proteins monitored by electrospray ionization mass spectrometry: a comparison of positive and negative ion modes

    Lars Konermann;D. J. Douglas

  • Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches.

    Lars Konermann;Xin Tong;Yan Pan

  • Hydrogen/Deuterium Exchange Mass Spectrometry with Top-Down Electron Capture Dissociation for Characterizing Structural Transitions of a 17 kDa Protein

    Jingxi Pan;Jun Han;Christoph H. Borchers;Lars Konermann

  • Protein-folding kinetics and mechanisms studied by pulse-labeling and mass spectrometry

    Lars Konermann;Douglas A. Simmons

  • Equilibrium unfolding of proteins monitored by electrospray ionization mass spectrometry: distinguishing two-state from multi-state transitions.

    Lars Konermann;D. J. Douglas

  • Cytochrome c folding kinetics studied by time-resolved electrospray ionization mass spectrometry.

    L Konermann;B A Collings;D J Douglas

  • Acid-induced denaturation of myoglobin studied by time-resolved electrospray ionization mass spectrometry.

    L. Konermann;F. I. Rosell;and A. G. Mauk;D. J. Douglas

  • Mass Spectrometry Methods for Studying Structure and Dynamics of Biological Macromolecules

    Lars Konermann;Siavash Vahidi;Modupeola A. Sowole

  • A capillary mixer with adjustable reaction chamber volume for millisecond time-resolved studies by electrospray mass spectrometry.

    Derek J Wilson;Lars Konermann

  • Pre-Steady State Kinetic Analysis of an Enzymatic Reaction Monitored by Time-Resolved Electrospray Ionization Mass Spectrometry†

    David L. Zechel;Lars Konermann;Stephen G. Withers;D. J. Douglas

  • Effects of pH on the kinetic reaction mechanism of myoglobin unfolding studied by time-resolved electrospray ionization mass spectrometry.

    Oyebola O. Sogbein;Douglas A. Simmons;Lars Konermann

  • On the Formation of Highly Charged Gaseous Ions from Unfolded Proteins by Electrospray Ionization

    Lars Konermann;Antony D. Rodriguez;Jiangjiang Liu

  • Modeling the Behavior of Coarse-Grained Polymer Chains in Charged Water Droplets: Implications for the Mechanism of Electrospray Ionization

    Elias Ahadi;Lars Konermann

  • Electron capture dissociation of electrosprayed protein ions for spatially resolved hydrogen exchange measurements.

    Jingxi Pan;Jun Han;Christoph H Borchers;Lars Konermann

Frequent Co-Authors

Donald J. Douglas
Donald J. Douglas University of British Columbia
Leonid S. Brown
Leonid S. Brown University of Guelph
Alfred R. Holzwarth
Alfred R. Holzwarth Vrije Universiteit Amsterdam
Christoph H. Borchers
Christoph H. Borchers McGill University
Gilles A. Lajoie
Gilles A. Lajoie University of Western Ontario
David W. Litchfield
David W. Litchfield University of Western Ontario
Thomas Surrey
Thomas Surrey The Francis Crick Institute
Neil L. Kelleher
Neil L. Kelleher Northwestern University
Miguel A. Valvano
Miguel A. Valvano Queen's University Belfast
Jérôme Cornil
Jérôme Cornil University of Mons

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