World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
50
Citations
11011
World Ranking
14265
National Ranking
388

Biology and Biochemistry

D-Index
53
Citations
13626
World Ranking
15986
National Ranking
557

Overview

Gilles A. Lajoie is affiliated with the University of Western Ontario in Canada. Their research spans multiple fields within biochemistry, genetics, and molecular biology, with a significant focus on medicine. The primary subfields of study include molecular biology, oncology, genetics, cancer research, and surgery.

The main topics covered by Gilles A. Lajoie's work include:

  • Ubiquitin and proteasome pathways
  • Mesenchymal stem cell research
  • Extracellular vesicles in disease
  • Cancer, hypoxia, and metabolism
  • Epigenetics and DNA methylation
  • Protein degradation and inhibitors
  • Cancer-related molecular pathways

The scientist has published extensively, contributing to journals and publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory) - 11 publications
  • Scientific Reports - 3 publications
  • International Journal of Molecular Sciences - 2 publications
  • The FASEB Journal - 2 publications
  • Stem Cells - 2 publications

Some recent papers by Gilles A. Lajoie include:

  • "Pillar-beam structures prevent layered cathode materials from destructive phase transitions," 2021, Nature Communications
  • "Structural and Functional Insights into GID/CTLH E3 Ligase Complexes," 2022, International Journal of Molecular Sciences
  • "Toward Low-Cost All-Organic and Biodegradable Li-Ion Batteries," 2020, Scientific Reports
  • "Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex-dependent regulation of glycolysis," 2021, The FASEB Journal
  • "Tandem SERS and MS/MS Profiling of Plasma Extracellular Vesicles for Early Ovarian Cancer Biomarker Discovery," 2024, ACS Sensors

Frequent collaborators include:

  • Tyler T. Cooper (19 joint publications)
  • Lynne-Marie Postovit (12 joint publications)
  • Matthew E. R. Maitland (11 joint publications)
  • Caroline Schild-Poulter (10 joint publications)
  • Miljan Kuljanin (7 joint publications)

Best Publications

  • Matrigel: A complex protein mixture required for optimal growth of cell culture

    Chris S. Hughes;Lynne M. Postovit;Gilles A. Lajoie

  • PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry

    Bin Ma;Kaizhong Zhang;Christopher Hendrie;Chengzhi Liang

  • PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification

    Jing Zhang;Lei Xin;Baozhen Shan;Weiwu Chen

  • IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro

    Sean C. Bendall;Morag H. Stewart;Pablo Menendez;Dustin George

  • A HUPO test sample study reveals common problems in mass spectrometry–based proteomics

    Alexander W. Bell;Eric W. Deutsch;Catherine E. Au;Robert E. Kearney

  • The Drosophila Nuclear Receptor E75 Contains Heme and Is Gas Responsive

    Jeff Reinking;Mandy M.S. Lam;Mandy M.S. Lam;Keith Pardee;Keith Pardee;Heidi M. Sampson;Heidi M. Sampson

  • Chitinase genes responsive to cold encode antifreeze proteins in winter cereals

    Sansun Yeh;Barbara A. Moffatt;Marilyn Griffith;Fei Xiong

  • Role of siderophore biosynthesis in virulence of Staphylococcus aureus: identification and characterization of genes involved in production of a siderophore.

    Suzanne E. Dale;Amanda Doherty-Kirby;Gilles Lajoie;David E. Heinrichs

  • Prevention of Amino Acid Conversion in SILAC Experiments with Embryonic Stem Cells

    Sean C. Bendall;Chris Hughes;Morag H. Stewart;Brad Doble

  • Inhibition of hydroxyapatite formation by osteopontin phosphopeptides.

    David A. Pampena;Karen A. Robertson;Olga Litvinova;Gilles Lajoie

  • Control of calcium oxalate crystal growth by face-specific adsorption of an osteopontin phosphopeptide.

    B Grohe;J O'Young;DA Ionescu;G Lajoie

  • Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus.

    Federico C. Beasley;Enrique D. Vinés;Jason C. Grigg;Qin Zheng

  • Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus

    Johnson Cheung;Federico C. Beasley;Suya Liu;Gilles A. Lajoie

  • Facile regioselective formation of thiopeptide linkages from oligopeptides with new thionation reagents

    G. Lajoie;F. Lépine;L. Maziak;B. Belleau

  • The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

    Keith I Pardee;Xiaohui Xu;Jeff Reinking;Jeff Reinking;Anja Schuetz

  • Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli.

    Ruslan Sanishvili;Alexander F. Yakunin;Roman A. Laskowski;Tatiana Skarina

  • Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindles.

    Julie Cahu;Aurelien Olichon;Christian Hentrich;Henry Schek

  • Matrix Gla protein inhibits ectopic calcification by a direct interaction with hydroxyapatite crystals.

    Jason O’Young;Yinyin Liao;Yizhi Xiao;Jari Jalkanen

  • Synthesis of a chiral serine aldehyde equivalent and its conversion to chiral .alpha.-amino acid derivatives

    Mark A. Blaskovich;Gilles A. Lajoie

  • A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response

    Huadong Liu;Marek Galka;Eiichiro Mori;Xuguang Liu

Frequent Co-Authors

Bin Ma
Bin Ma University of Waterloo
Kaizhong Zhang
Kaizhong Zhang University of Western Ontario
Sean C. Bendall
Sean C. Bendall Stanford University
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Mickie Bhatia
Mickie Bhatia McMaster University
Mikko Karttunen
Mikko Karttunen University of Western Ontario
David W. Litchfield
David W. Litchfield University of Western Ontario
Shawn S.-C. Li
Shawn S.-C. Li University of Western Ontario
David E. Heinrichs
David E. Heinrichs University of Western Ontario
Haixia Zhang
Haixia Zhang Peking University

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