World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Biology and Biochemistry
USA
2026

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Best Scientists

D-Index
215
Citations
182004
World Ranking
164
National Ranking
111

Biology and Biochemistry

D-Index
220
Citations
189031
World Ranking
20
National Ranking
17

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award

Overview

John R. Yates is affiliated with the Scripps Research Institute in the United States. Their work spans primarily the fields of Biochemistry, Genetics, and Molecular Biology, with a focus on molecular biology as well as related subfields such as the history and philosophy of science, spectroscopy, genetics, and cell biology.

The topics covered in their research include academic writing and publishing, advanced proteomics techniques and applications, RNA research and splicing, RNA modifications and cancer, HIV research and treatment, RNA and protein synthesis mechanisms, and mass spectrometry techniques and applications.

Yates has contributed to several prominent scientific journals and venues. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Journal of the American Society for Mass Spectrometry
  • Cell Reports
  • Science

Their recent papers cover a range of topics and appear in high-impact journals:

  • "The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein," 2021, Nature Communications
  • "Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate," 2020, Science
  • "HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells," 2021, Science
  • "Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments," 2023, Nature Methods
  • "Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase," 2020, Cell

Yates collaborates frequently with a set of coauthors, including Joseph A. Loo, Cynthia J. Burrows, Shu Wang, Hyun Jae Kim, and Gerald J. Meyer. These partnerships have been prolific over many publications.

Best Publications

  • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database.

    Jimmy K. Eng;Ashley L. McCormack;John R. Yates

  • Large-scale analysis of the yeast proteome by multidimensional protein identification technology.

    Michael P. Washburn;Dirk Wolters;John R. Yates;John R. Yates

  • Direct analysis of protein complexes using mass spectrometry

    Andrew J. Link;Jimmy Eng;David M. Schieltz;Edwin Carmack

  • A Model for Random Sampling and Estimation of Relative Protein Abundance in Shotgun Proteomics

    Hongbin Liu;Hongbin Liu;Rovshan G. Sadygov;John R. Yates;John R. Yates

  • Wnt proteins are lipid-modified and can act as stem cell growth factors

    Karl Willert;Jeffrey D. Brown;Esther Danenberg;Andrew W. Duncan

  • Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

    Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas

  • An Automated Multidimensional Protein Identification Technology for Shotgun Proteomics

    Dirk A. Wolters;Michael P. Washburn;John R. Yates

  • Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

    Marjon van Slegtenhorst;Ronald de Hoogt;Caroline Hermans;Mark Nellist

  • A proteomic view of the Plasmodium falciparum life cycle

    Laurence Florens;Michael P. Washburn;J. Dale Raine;Robert M. Anthony

  • Method to Correlate Tandem Mass Spectra of Modified Peptides to Amino Acid Sequences in the Protein Database

    John R. Yates;Jimmy K. Eng;Ashley L. McCormack;David. Schieltz

  • Protein Analysis by Shotgun/Bottom-up Proteomics

    Yaoyang Zhang;Bryan R. Fonslow;Bing Shan;Moon-Chang Baek;Moon-Chang Baek

  • Protein sequencing by tandem mass spectrometry

    Donald F. Hunt;John R. Yates;Jeffrey Shabanowitz;Scott Winston

  • Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.

    Michael J. Carrozza;Bing Li;Laurence Florens;Tamaki Suganuma

  • The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

    James P Carney;James P Carney;Richard S Maser;Heidi Olivares;Elizabeth M Davis

  • Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

    John R. Yates;Cristian I. Ruse;Aleksey Nakorchevsky

  • Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

    Debra Burdick;Brian Soreghan;Michael Kwon;Joseph Kosmoski

  • Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26S Proteasome

    Rati Verma;L. Aravind;Robert Oania;W. Hayes McDonald

  • Current Protocols in Bioinformatics

    Alex Bateman;William R. Pearson;Lincoln D. Stein;Gary D. Stormo

  • Mass spectrometry and the age of the proteome.

    John R. Yates

  • Clinical Features and Natural History of von Hippel-Lindau Disease

    E R Maher;J R Yates;R Harries;Caroline Benjamin

Frequent Co-Authors

Joseph A. Loo
Joseph A. Loo University of California, Los Angeles
Jonathan V. Sweedler
Jonathan V. Sweedler University of Illinois at Urbana-Champaign
Shu Wang
Shu Wang Chinese Academy of Sciences
Gilbert C. Walker
Gilbert C. Walker University of Toronto
Stuart J. Rowan
Stuart J. Rowan University of Chicago
Prashant V. Kamat
Prashant V. Kamat University of Notre Dame
Marc A. Hillmyer
Marc A. Hillmyer University of Minnesota
Vincent M. Rotello
Vincent M. Rotello University of Massachusetts Amherst
Gregory D. Scholes
Gregory D. Scholes Princeton University

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