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D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
25980
World Ranking
2846
National Ranking
1461

Overview

Robert L. Hettich is affiliated with Oak Ridge National Laboratory in the United States. Their research spans several areas within biochemistry, genetics, molecular biology, and environmental science, contributing extensively to the understanding of microbial ecology, metabolic engineering, and related fields.

The scientist's publication record includes over 100 works in biochemistry, genetics, and molecular biology, alongside 63 publications in environmental science. Their subfields of study primarily focus on molecular biology and ecology, with additional specialization in plant science, biomedical engineering, and spectroscopy.

Hettich's research topics address diverse aspects of microbial systems and biochemical processes. Key thematic areas include:

  • Microbial Community Ecology and Physiology
  • Microbial Metabolic Engineering and Bioproduction
  • Genomics and Phylogenetic Studies
  • Biofuel production and bioconversion
  • Advanced Proteomics Techniques and Applications
  • Gut microbiota and health
  • Methane Hydrates and Related Phenomena

Their recent prominent papers demonstrate a focus on industrial applications and environmental microbiology. Notable works include:

  • Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale, 2022, Nature Biotechnology
  • Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation, 2021, Annual Review of Chemical and Biomolecular Engineering
  • Active sulfur cycling in the terrestrial deep subsurface, 2020, The ISME Journal
  • Outer membrane vesicles catabolize lignin-derived aromatic compounds in Pseudomonas putida KT2440, 2020, Proceedings of the National Academy of Sciences
  • Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows, 2021, Nature Communications

Frequent collaborators in their research include Richard J. Giannone, Paul E. Abraham, Him K. Shrestha, Suresh Poudel, and Samantha L. Peters. This network of coauthors reflects interdisciplinary efforts extending across various subfields of microbiology and molecular biology.

Hettich's publications are also frequently found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Frontiers in Microbiology, The ISME Journal, and Nature Communications. These venues indicate an engagement with both preprint dissemination and peer-reviewed research across microbiology and molecular sciences.

Best Publications

  • Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla

    Michael A. Mahowald;Federico E. Rey;Henning Seedorf;Peter J. Turnbaugh

  • Community Proteomics of a Natural Microbial Biofilm

    Rachna J. Ram;Nathan C. VerBerkmoes;Michael P. Thelen;Michael P. Thelen;Gene W. Tyson

  • Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla.

    Kelly C. Wrighton;Brian C. Thomas;Itai Sharon;Christopher S. Miller

  • Shotgun metaproteomics of the human distal gut microbiota.

    Nathan C Verberkmoes;Alison L Russell;Manesh Shah;Adam Godzik

  • Fullerenes from the geological environment.

    Peter R. Buseck;Semeon J. Tsipursky;Robert Hettich

  • Detecting Differential and Correlated Protein Expression in Label-Free Shotgun Proteomics

    Bing Zhang;Nathan C. Verberkmoes;Michael A. Langston;Edward Uberbacher

  • The environmental controls that govern the end product of bacterial nitrate respiration

    Beate Kraft;Halina E. Tegetmeyer;Halina E. Tegetmeyer;Ritin Sharma;Ritin Sharma;Martin G. Klotz;Martin G. Klotz

  • Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease

    Alison R. Erickson;Brandi L. Cantarel;Regina Lamendella;Youssef El Darzi

  • Enigmatic, ultrasmall, uncultivated Archaea

    Brett J. Baker;Luis R. Comolli;Gregory J. Dick;Loren J. Hauser

  • Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

    Jeanette L. Gehrig;Siddarth Venkatesh;Hao Wei Chang;Matthew C. Hibberd

  • Systematic Comparison of Label-Free, Metabolic Labeling, and Isobaric Chemical Labeling for Quantitative Proteomics on LTQ Orbitrap Velos

    Zhou Li;Rachel M Adams;Karuna Chourey;Gregory {Greg} B Hurst

  • Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans.

    Michael L. Patnode;Zachary W. Beller;Nathan D. Han;Jiye Cheng

  • Systems biology: Functional analysis of natural microbial consortia using community proteomics.

    Nathan C Verberkmoes;Vincent Denef;Robert {Bob} L Hettich;Jillian F. Banfield

  • Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome

    Nathan P. McNulty;Meng Wu;Alison R. Erickson;Chongle Pan

  • Strain-resolved community proteomics reveals recombining genomes of acidophilic bacteria

    Ian Lo;Vincent J. Denef;Nathan C. VerBerkmoes;Manesh B. Shah

  • Doubly charged negative ions of carbon-60.

    R. L. Hettich;R. N. Compton;R. H. Ritchie

  • A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world.

    Xiaohan Yang;John C. Cushman;Anne M. Borland;Anne M. Borland;Erika J. Edwards

  • Gas-phase photodissociation of organometallic ions. Bond energy and structure determinations

    R. L. Hettich;T. C. Jackson;E. M. Stanko;B. S. Freiser

  • Molecular Dynamics of the Shewanella oneidensis Response to Chromate Stress

    Steven D Brown;Melissa R Thompson;Nathan C Verberkmoes;Karuna Chourey

  • Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities.

    Robert L. Hettich;Chongle Pan;Karuna Chourey;Richard J. Giannone

Frequent Co-Authors

Nathan C Verberkmoes
Nathan C Verberkmoes Oak Ridge National Laboratory
Jillian F. Banfield
Jillian F. Banfield University of California, Berkeley
Robert N. Compton
Robert N. Compton University of Tennessee at Knoxville
Frank E. Löffler
Frank E. Löffler University of Tennessee at Knoxville
Steven D. Brown
Steven D. Brown LanzaTech (New Zealand)
Timothy J. Tschaplinski
Timothy J. Tschaplinski Oak Ridge National Laboratory
Adam M. Guss
Adam M. Guss Oak Ridge National Laboratory
Mircea Podar
Mircea Podar Oak Ridge National Laboratory
Lee R. Lynd
Lee R. Lynd Dartmouth College

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