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Joseph B. Bolen

Joseph B. Bolen

Takeda (Japan)
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
25744
World Ranking
3487
National Ranking
213

Joseph B. Bolen publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Joseph B. Bolen sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 167 publications — 35th percentile

35% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Joseph B. Bolen D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Joseph B. Bolen sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 83 D-Index — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Joseph B. Bolen is affiliated with Takeda in Japan, contributing to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

Their work encompasses several subfields including Molecular Biology, Immunology, Radiology, Nuclear Medicine and Imaging, and Computational Theory and Mathematics. The scientist's research focuses on multiple key topics such as Immunotherapy and Immune Responses, vaccines and immunoinformatics approaches, Monoclonal and Polyclonal Antibodies Research, Galectins and Cancer Biology, Toxin Mechanisms and Immunotoxins, Bioinformatics and Genomic Networks, and Computational Drug Discovery Methods.

Joseph B. Bolen has been involved in publishing scientific articles in several venues, notably:

  • Frontiers in Cell and Developmental Biology
  • Regular and Young Investigator Award Abstracts
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine Open

The recent scientific papers authored or co-authored by Joseph B. Bolen include:

  • "Progress Toward Identifying Exact Proxies for Predicting Response to Immunotherapies," 2020, Frontiers in Cell and Developmental Biology
  • "482 Phase1/2 study of an anti-galectin-9 antibody, LYT-200, in patients with metastatic solid tumors," 2021, Regular and Young Investigator Award Abstracts
  • "Scale-free structure of cancer networks and their vulnerability to hub-directed combination therapy," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "P453: PTEN and WDR19 variants in a neonate with brain and cutaneous anomalies," 2025, Genetics in Medicine Open

The scientist has collaborated with a range of co-authors including Aleksandra Filipović, George Miller, Zev Wainber, and Judy Wang.

Best Publications

  • An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

    Teresa A. Soucy;Peter G. Smith;Michael A. Milhollen;Allison J. Berger

  • The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

    André Veillette;Michael A. Bookman;Eva M. Horak;Joseph B. Bolen

  • Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

    André Veillette;Michael A. Bookman;Eva M. Horak;Lawrence E. Samelson

  • Syk tyrosine kinase required for mouse viability and B-cell development

    Alec M. Cheng;Bruce Rowley;William Pao;Adrian Hayday

  • Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases.

    E Eiseman;J B Bolen

  • Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

    James E. Brownell;Michael D. Sintchak;James M. Gavin;Hua Liao

  • Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

    Mark G. Manfredi;Jeffrey A. Ecsedy;Kristan A. Meetze;Suresh K. Balani

  • Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.

    Anne L. Burkhardt;Mark Brunswick;Joseph B. Bolen;James J. Mond

  • Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets.

    Min-Mei Huang;Joseph B. Bolen;John W. Barnwell;Sanford J. Shattil

  • Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases.

    Cheryl L. Miller;Anne L. Burkhardt;Jennifer H. Lee;Becky Stealey

  • Activation of pp60c-src protein kinase activity in human colon carcinoma.

    Joseph B. Bolen;Andre Veillette;Arnold M. Schwartz;Virginia Deseau

  • Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn.

    I Stefanová;M L Corcoran;E M Horak;L M Wahl

  • Nonreceptor tyrosine protein kinases.

    Bolen Jb

  • Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

    R. B. Rowley;A. L. Burkhardt;Hann-Guang Chao;G. R. Matsueda

  • Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

    Joseph B. Bolen;Carol J. Thiele;Mark A. Israel;Wes Yonemoto

  • Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement

    S. J. Saouaf;Sandeep Mahajan;R. B. Rowley;S. A. Kut

  • Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases

    FM Uckun;WE Evans;CJ Forsyth;KG Waddick

  • MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma

    Michael A. Milhollen;Tary Traore;Jennifer Adams-Duffy;Michael P. Thomas

  • Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues.

    N Rosen;J B Bolen;A M Schwartz;P Cohen

  • Characterization of Alisertib (MLN8237), An Investigational Small Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

    Mark G. Manfredi;Jeffrey A. Ecsedy;Arijit Chakravarty;Lee Silverman

Frequent Co-Authors

André Veillette
André Veillette University of Montreal
Neal Rosen
Neal Rosen Memorial Sloan Kettering Cancer Center
Barbara M. Bröker
Barbara M. Bröker Greifswald University Hospital
Ivan D. Horak
Ivan D. Horak Freie Universität Berlin
Jeffrey A. Ledbetter
Jeffrey A. Ledbetter University of Washington
Tomohiro Kurosaki
Tomohiro Kurosaki Osaka University
Gary L. Schieven
Gary L. Schieven Genesis Biotechnology Group
Terrence R. Burke
Terrence R. Burke National Institutes of Health
Helmut Fickenscher
Helmut Fickenscher Kiel University
Joan S. Brugge
Joan S. Brugge Harvard University

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Richard Longnecker

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Tomohiro Kurosaki

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Robert L. Geahlen

Robert L. Geahlen

Purdue University West Lafayette

Publications: 46

Michael Reth

Michael Reth

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Publications: 38

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Christopher E. Rudd

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Steve P. Watson

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John C. Cambier

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Publications: 33

Lawrence E. Samelson

Lawrence E. Samelson

National Institutes of Health

Publications: 32

Victor L. J. Tybulewicz

Victor L. J. Tybulewicz

The Francis Crick Institute

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