World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
100
Citations
38667
World Ranking
1507
National Ranking
851

Lawrence E. Samelson publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Lawrence E. Samelson sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 235 publications — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Lawrence E. Samelson D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Lawrence E. Samelson sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 100 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Lawrence E. Samelson is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions to medicine. The scientist's work spans multiple subfields, including immunology, oncology, molecular biology, cell biology, and electrical and electronic engineering.

The main topics covered in their research include:

  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Ubiquitin and proteasome pathways
  • Monoclonal and Polyclonal Antibodies Research
  • Polyamine Metabolism and Applications
  • Microtubule and mitosis dynamics

Recent publications by Lawrence E. Samelson demonstrate an emphasis on immune cell signaling and molecular mechanisms within T cells. These include:

  • "Bypassing ubiquitination enables LAT recycling to the cell surface and enhanced signaling in T cells," 2020, PLoS ONE
  • "Microclusters as T Cell Signaling Hubs: Structure, Kinetics, and Regulation," 2021, Frontiers in Cell and Developmental Biology
  • "In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells," 2022, Journal of Biological Chemistry
  • "Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling," 2023, Nature Communications
  • "Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components," 2020, Journal of Biological Chemistry

Frequent co-authors collaborating with Lawrence E. Samelson include Lakshmi Balagopalan, Katherine M. McIntire, Junya Wada, Jason Yi, and Neriah Alvinez. These collaborations have contributed to the breadth and depth of their research output.

The scientist has published extensively in several venues, with repeated contributions to the Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, PLoS ONE, and Frontiers in Cell and Developmental Biology.

Recognition for their work includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2012 and membership in the Association of American Physicians.

Best Publications

  • Identification of a monoclonal antibody specific for a murine T3 polypeptide

    Oberdan Leo;Michele Foo;David H. Sachs;Lawrence E. Samelson

  • LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

    Weiguo Zhang;Joanne Sloan-Lancaster;Jason Kitchen;Ronald P Trible

  • LAT Palmitoylation: Its Essential Role in Membrane Microdomain Targeting and Tyrosine Phosphorylation during T Cell Activation

    Weiguo Zhang;Ronald P Trible;Lawrence E Samelson

  • Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

    André Veillette;Michael A. Bookman;Eva M. Horak;Lawrence E. Samelson

  • Molecular Basis of T Cell Inactivation by CTLA-4

    Kyung Mi Lee;Ellen Chuang;Matthew Griffin;Roli Khattri

  • Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

    Lawrence E. Samelson;Andrew F. Phillips;Elise T. Luong;Richard D. Klausner

  • Signal Transduction Mediated by the T Cell Antigen Receptor: The Role of Adapter Proteins*

    Lawrence E. Samelson

  • Complex Complexes: Signaling at the TCR

    Ronald L Wange;Lawrence E Samelson

  • T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

    Stephen C. Bunnell;David I. Hong;Julia R. Kardon;Tetsuo Yamazaki

  • Essential Role of LAT in T Cell Development

    Weiguo Zhang;Connie L Sommers;Deborah N Burshtyn;Christopher C Stebbins

  • LAT Is Required for TCR-Mediated Activation of PLCγ1 and the Ras Pathway

    Timothy S Finco;Theresa Kadlecek;Weiguo Zhang;Lawrence E Samelson

  • In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice.

    R D Gordon;E Simpson;L E Samelson

  • Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

    Joaquín Madrenas;Ronald L. Wange;Jennifer L. Wang;Noah Isakov

  • Dynamic Actin Polymerization Drives T Cell Receptor–Induced Spreading: A Role for the Signal Transduction Adaptor LAT

    Stephen C. Bunnell;Veena Kapoor;Ronald P. Trible;Weiguo Zhang

  • T cell antigen receptor activation pathways: the tyrosine kinase connection.

    Richard D. Klausner;Lawrence E. Samelson

  • Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.

    Carl H. June;Mary C. Fletcher;Jeffrey A. Ledbetter;Lawrence E. Samelson

  • Association of Grb2, Gads, and Phospholipase C-γ1 with Phosphorylated LAT Tyrosine Residues EFFECT OF LAT TYROSINE MUTATIONS ON T CELL ANTIGEN RECEPTOR-MEDIATED SIGNALING

    Weiguo Zhang;Weiguo Zhang;Ronald P. Trible;Minghua Zhu;Stanley K. Liu

  • Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation

    Valentino Parravicini;Valentino Parravicini;Massimo Gadina;Martina Kovarova;Martina Kovarova;Sandra Odom

  • Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

    Lawrence E. Samelson;Maitray D. Patel;Allan M. Weissman;Joe B. Harford

  • Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction.

    Carl H. June;Mary C. Fletcher;Jeffrey A. Ledbetter;Gary L. Schieven

Frequent Co-Authors

Weiguo Zhang
Weiguo Zhang Duke University
Paul E. Love
Paul E. Love National Institutes of Health
Carl H. June
Carl H. June University of Pennsylvania
Ronald H. Schwartz
Ronald H. Schwartz National Institutes of Health
John J. O'Shea
John J. O'Shea National Institutes of Health
Allan M. Weissman
Allan M. Weissman National Institutes of Health
Ettore Appella
Ettore Appella National Institutes of Health
Peter Schuck
Peter Schuck National Institutes of Health
Juan S. Bonifacino
Juan S. Bonifacino National Institutes of Health

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