What is he best known for?
The fields of study he is best known for:
- Gene
- Signal transduction
- Phosphorylation
Lawrence E. Samelson focuses on T-cell receptor, Cell biology, Tyrosine phosphorylation, Molecular biology and T cell.
Lawrence E. Samelson interconnects Receptor, Tyrosine, Biochemistry and Jurkat cells in the investigation of issues within T-cell receptor.
His research is interdisciplinary, bridging the disciplines of ZAP70 and Cell biology.
His Tyrosine phosphorylation research incorporates themes from Tyrosine kinase and Protein tyrosine phosphatase.
His Molecular biology study integrates concerns from other disciplines, such as Proto-oncogene tyrosine-protein kinase Src, CD3, Antigen, Receptor complex and Antibody.
His work in T cell addresses subjects such as Cytotoxic T cell, which are connected to disciplines such as T lymphocyte and Immunology.
His most cited work include:
- Identification of a monoclonal antibody specific for a murine T3 polypeptide (1347 citations)
- LAT: The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation (1141 citations)
- LAT Palmitoylation: Its Essential Role in Membrane Microdomain Targeting and Tyrosine Phosphorylation during T Cell Activation (789 citations)
What are the main themes of his work throughout his whole career to date?
T-cell receptor, Cell biology, Molecular biology, T cell and Signal transduction are his primary areas of study.
His biological study spans a wide range of topics, including Jurkat cells, Biochemistry, CD8, Tyrosine phosphorylation and Cytotoxic T cell.
His Tyrosine phosphorylation study combines topics from a wide range of disciplines, such as Tyrosine kinase, Protein phosphorylation and Protein tyrosine phosphatase.
The study incorporates disciplines such as Receptor, Immunology and Linker for Activation of T cells in addition to Cell biology.
In his study, which falls under the umbrella issue of Molecular biology, Antibody, Cell surface receptor and Immune system is strongly linked to Antigen.
The Signal transduction study which covers Thymocyte that intersects with Cellular differentiation.
He most often published in these fields:
- T-cell receptor (54.17%)
- Cell biology (49.54%)
- Molecular biology (35.19%)
What were the highlights of his more recent work (between 2010-2021)?
- Cell biology (49.54%)
- T cell (34.26%)
- T-cell receptor (54.17%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, T cell, T-cell receptor, Signal transduction and Linker for Activation of T cells.
His Cell biology research is multidisciplinary, relying on both Photoactivated localization microscopy, Receptor and Genetically modified mouse.
His studies in T cell integrate themes in fields like Cell, Biophysics, Ubiquitin and Phosphorylation.
Lawrence E. Samelson has included themes like Jurkat cells, Cytotoxic T cell, CD8 and Cytokine in his T-cell receptor study.
His Signal transduction research includes elements of Thymocyte, Adapter and Actin.
His Linker for Activation of T cells research is multidisciplinary, incorporating perspectives in Molecular biology and Membrane protein.
Between 2010 and 2021, his most popular works were:
- Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor (229 citations)
- Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance (77 citations)
- Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells (72 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Signal transduction
- Immune system
Lawrence E. Samelson mainly focuses on T cell, Cell biology, T-cell receptor, Signal transduction and Linker for Activation of T cells.
Within one scientific family, he focuses on topics pertaining to Cell under T cell, and may sometimes address concerns connected to Phosphorylation, In vitro, Adapter and SH2 domain.
His research integrates issues of Tumor microenvironment, Jurkat cells, Cancer research and Receptor in his study of T-cell receptor.
The Signal transduction study combines topics in areas such as Thymocyte, Immunology and Binding site.
His Thymocyte research is multidisciplinary, incorporating elements of Molecular biology and Son of Sevenless.
His Linker for Activation of T cells study frequently links to other fields, such as Signal transducing adaptor protein.
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