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Biology and Biochemistry

D-Index
57
Citations
12520
World Ranking
13775
National Ranking
5829

Overview

Virginia F. Borges is affiliated with the University of Colorado Boulder in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on oncology-related studies.

The scientist's main subfields of study include Oncology, Pulmonary and Respiratory Medicine, Cancer Research, Genetics, and Public Health, Environmental and Occupational Health. Their research covers major topics such as Advanced Breast Cancer Therapies, Breast Cancer Treatment Studies, Cancer Risks and Factors, HER2/EGFR in Cancer Research, Cancer Treatment and Pharmacology, Reproductive Biology and Fertility, and BRCA gene mutations in cancer.

Recent publications reflect Virginia F. Borges's focus on breast cancer and cancer therapies. Notable papers include:

  • Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial (2020, Journal of Clinical Oncology)
  • Tucatinib versus placebo added to trastuzumab and capecitabine for patients with pretreated HER2+ metastatic breast cancer with and without brain metastases (HER2CLIMB): final overall survival analysis (2021, Annals of Oncology)
  • Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer (2023, New England Journal of Medicine)
  • NRG-BR002: A phase IIR/III trial of standard of care systemic therapy with or without stereotactic body radiotherapy (SBRT) and/or surgical resection (SR) for newly oligometastatic breast cancer (2022, Journal of Clinical Oncology)
  • Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases (2022, JAMA Oncology)

Frequent co-authors in Virginia F. Borges's work include:

  • Ann H. Partridge
  • Kathryn J. Ruddy
  • Steven E. Come
  • Lidia Schapira
  • Shoshana M. Rosenberg

The scientist regularly publishes in several key venues, notably:

  • Cancer Research
  • Journal of Clinical Oncology
  • Clinical Cancer Research
  • Annals of Oncology
  • npj Breast Cancer

This overview presents Virginia F. Borges as a researcher contributing extensively to breast cancer therapy and related oncological studies, with a significant body of work addressing clinical outcomes, treatment modalities, and cancer biology within a multidisciplinary context.

Best Publications

  • Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer.

    Rashmi K Murthy;Sherene Loi;Alicia Okines;Elisavet Paplomata

  • Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses.

    David Avigan;Baldev Vasir;Jianlin Gong;Virginia Borges

  • Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

    Traci R. Lyons;Jenean O'Brien;Virginia F. Borges;Virginia F. Borges;Matthew W. Conklin

  • Preoperative Therapy With Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for HER2 Overexpressing Stage II or III Breast Cancer: A Pilot Study

    Harold J. Burstein;Lyndsay N. Harris;Rebecca Gelman;Susan C. Lester

  • Prospective Study of Fertility Concerns and Preservation Strategies in Young Women With Breast Cancer

    Kathryn J. Ruddy;Shari I. Gelber;Rulla M. Tamimi;Elizabeth S. Ginsburg

  • Intracranial efficacy and survival with tucatinib plus trastuzumab and capecitabine for previously treated HER2-positive breast cancer with brain metastases in the HER2CLIMB trial

    Nancy U. Lin;Virginia Borges;Carey Anders;Rashmi K. Murthy

  • NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1+ or 2+

    Louis Fehrenbacher;Reena S. Cecchini;Charles E. Geyer;Priya Rastogi

  • Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland across Species

    Jenean O'Brien;Traci Lyons;Jenifer Monks;M. Scott Lucia;M. Scott Lucia

  • Pregnancy and Breast Cancer: when They Collide

    Traci R. Lyons;Pepper J. Schedin;Virginia F. Borges

  • Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

    Peter F. Coccia;Alberto S. Pappo;Lynda Beaupin;Virginia F. Borges

  • Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer.

    Eryn B. Callihan;Dexiang Gao;Sonali Jindal;Traci R. Lyons

  • Parity, lactation, and breast cancer subtypes in African American women: results from the AMBER Consortium.

    Julie R. Palmer;Emma Viscidi;Melissa A. Troester;Melissa A. Troester;Chi Chen Hong

  • Microenvironment of the involuting mammary gland mediates mammary cancer progression.

    Pepper Schedin;Jenean O’Brien;Michael Rudolph;Torsten Stein

  • Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab.

    Richard P. Tobin;Kimberly R. Jordan;William A. Robinson;William A. Robinson;Dana Davis

  • Tucatinib with capecitabine and trastuzumab in advanced HER2-positive metastatic breast cancer with and without brain metastases: a non-randomised, open-label, phase 1b study

    Rashmi Murthy;Virginia F Borges;Alison Conlin;Jorge Chaves

  • Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression.

    Holly A. Martinson;Sonali Jindal;Clarissa Durand-Rougely;Virginia F. Borges

  • Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients

    Kimberly R. Jordan;Rodabe N. Amaria;Oscar Ramirez;Eryn B. Callihan

  • Phase I Study of ONT-380, a HER2 Inhibitor, in Patients with HER2+-Advanced Solid Tumors, with an Expansion Cohort in HER2+ Metastatic Breast Cancer (MBC).

    Stacy L. Moulder;Virginia F. Borges;Tara Baetz;Tessa Mcspadden

  • Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer.

    Traci R. Lyons;Virginia F. Borges;Virginia F. Borges;Courtney B. Betts;Qiuchen Guo

  • BRCA1 and BRCA2 mutation testing in young women with breast cancer

    Shoshana M. Rosenberg;Kathryn J. Ruddy;Rulla M. Tamimi;Shari Gelber

Frequent Co-Authors

Pepper Schedin
Pepper Schedin Oregon Health & Science University
Ann H. Partridge
Ann H. Partridge Harvard University
Rulla M. Tamimi
Rulla M. Tamimi Cornell University
Anthony D. Elias
Anthony D. Elias University of Colorado Boulder
Eric P. Winer
Eric P. Winer Yale University
Ian E. Krop
Ian E. Krop Harvard University
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Martin D. McCarter
Martin D. McCarter University of Colorado Anschutz Medical Campus
Lisa A. Carey
Lisa A. Carey University of North Carolina at Chapel Hill
Gabriel N. Hortobagyi
Gabriel N. Hortobagyi The University of Texas MD Anderson Cancer Center

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