World's Best Scientists 2026 revealed!

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Microbiology

D-Index
69
Citations
14062
World Ranking
2098
National Ranking
122

Molecular Biology

D-Index
69
Citations
13821
World Ranking
1488
National Ranking
45

Overview

Marie Malissen is affiliated with Aix-Marseille University in France and works extensively in immunology and microbiology, as well as medicine. Their research focuses on T-cell and B-cell immunology, immune cell function and interaction, and CAR-T cell therapy research, among other specialized topics.

Their work covers a variety of specific areas, including:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Chemokine receptors and signaling
  • IgG4-Related and Inflammatory Diseases
  • CRISPR and Genetic Engineering
  • Atherosclerosis and Cardiovascular Diseases

Marie Malissen has published papers in several fields, mainly focusing on immunology, oncological research, molecular biology, rheumatology, and epidemiology. Their contributions span from fundamental immunological mechanisms to clinical applications.

Frequent publication venues include:

  • The Journal of Experimental Medicine
  • Journal of Visualized Experiments
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Proceedings of the National Academy of Sciences

Notable recent publications include:

  • High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome, 2021, Proceedings of the National Academy of Sciences
  • The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation, 2020, The Journal of Experimental Medicine
  • LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN 2 as a regulator of effector functions, 2020, Molecular Systems Biology
  • ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding, 2021, EMBO Reports
  • Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis, 2021, Arthritis Research & Therapy

Marie Malissen collaborates frequently with a number of coauthors, including:

  • Bernard Malissen
  • Yinming Liang
  • Lichen Zhang
  • Liaoxun Lu
  • Yanrong Gu

Best Publications

  • Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction

    Günther Schönrich;Ulrich Kalinke;Frank Momburg;Marie Malissen

  • Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.

    M. Malissen;A. Gillet;L. Ardouin;G. Bouvier

  • Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

    Marie Malissen;Karyl Minard;Shelley Mjolsness;Mitchell Kronenberg

  • The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9

    Marc-André Wurbel;Jean-Marc Philippe;Catherine Nguyen;Genevieve Victorero

  • Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies

    Takuro Arimura;Anne Helbling-Leclerc;Catherine Massart;Shaida Varnous

  • Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

    Marc-André Wurbel;Marie Malissen;Delphine Guy-Grand;Eric Meffre

  • Regulation of TCR α and β gene allelic exclusion during T-cell development

    Marie Malissen;Jeannine Trucy;Evelyne Jouvin-Marche;Pierre-André Cazenave

  • The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

    Gerald Siu;Stephen P. Clark;Yasunobu Yoshikai;Marie Malissen

  • Induction of T Helper Type 2 Immunity by a Point Mutation in the LAT Adaptor

    Enrique Aguado;Sylvie Richelme;Selene Nuñez-Cruz;Arkadiusz Miazek

  • Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

    Baptiste N. Jaeger;Jean Donadieu;Céline Cognet;Claire Bernat;Claire Bernat;Claire Bernat

  • Exon/intron organization and complete nucleotide sequence of an HLA gene

    Marie Malissen;Bernard Malissen;Bertrand R. Jordan

  • Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

    Tomáš Brdička;Martin Imrich;Pavla Angelisová;Naděžda Brdičková

  • A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

    Marie Malissen;Jeannine Trucy;François Letourneur;Najet Rebai

  • Visualization of the earliest steps of gammadelta T cell development in the adult thymus.

    Immo Prinz;Amandine Sansoni;Adrien Kissenpfennig;Adrien Kissenpfennig;Laurence Ardouin

  • T cell development in mice lacking the CD3-zeta/eta gene.

    M Malissen;A Gillet;B Rocha;J Trucy

  • The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans

    Nicolette Caccia;Mitchell Kronenberg;Debra Saxe;Regina Haars

  • Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses

    Emilie Narni-Mancinelli;Emilie Narni-Mancinelli;Emilie Narni-Mancinelli;Baptiste N. Jaeger;Baptiste N. Jaeger;Baptiste N. Jaeger;Claire Bernat;Claire Bernat;Claire Bernat;Aurore Fenis;Aurore Fenis;Aurore Fenis

  • Rearrangement and transcription of the β-chain genes of the T-cell antigen receptor in different types of murine lymphocytes

    Mitchell Kronenberg;Joan Goverman;Regina Haars;Marie Malissen

  • T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α - and β -genes

    Horst Blüthmann;Pawel Kisielow;Pawel Kisielow;Yasushi Uematsu;Marie Malissen

  • Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells.

    Ying Wang;Adrien Kissenpfennig;Michael Mingueneau;Sylvie Richelme

Frequent Co-Authors

Bernard Malissen
Bernard Malissen Aix-Marseille University
Leroy Hood
Leroy Hood University of Washington
Anne-Marie Schmitt-Verhulst
Anne-Marie Schmitt-Verhulst Centre d’Immunologie de Marseille-Luminy
Eric Vivier
Eric Vivier Aix-Marseille University
Bernd Arnold
Bernd Arnold German Cancer Research Center
Philippe Naquet
Philippe Naquet Grenoble Alpes University
Adrien Kissenpfennig
Adrien Kissenpfennig Queen's University Belfast
Pierre-André Cazenave
Pierre-André Cazenave Institut Pasteur
Frank Momburg
Frank Momburg German Cancer Research Center
Odile Burlet-Schiltz
Odile Burlet-Schiltz Federal University of Toulouse Midi-Pyrénées

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