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Immunology
USA
2026

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Best Scientists

D-Index
171
Citations
112179
World Ranking
838
National Ranking
503

Immunology

D-Index
174
Citations
115277
World Ranking
46
National Ranking
33

Medicine

D-Index
175
Citations
115462
World Ranking
435
National Ranking
262

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2020 - AAI Excellence in Mentoring Award, American Association of Immunologists
  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2013 - Member of the National Academy of Medicine (NAM)
  • 2006 - Fellow of the American Academy of Arts and Sciences
  • 1997 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Jeffrey A. Bluestone is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on Immunology, Oncology, Genetics, Molecular Biology, and Endocrinology, Diabetes and Metabolism.

The scientist's work covers various main topics, including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Diabetes and associated disorders
  • Cancer Immunotherapy and Biomarkers
  • Pancreatic function and diabetes
  • Diabetes Management and Research

Frequent co-authors in their publications include:

  • Qizhi Tang
  • Arabella Young
  • Shen Dong
  • Kevan C. Herold
  • Patrick Ho

Key recent papers authored or co-authored by Bluestone are:

  • Multiple early factors anticipate post-acute COVID-19 sequelae, 2022, Cell
  • Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19, 2020, Cell
  • Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials, 2020, The Lancet
  • Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis, 2020, Science Immunology
  • CRISPR screen in regulatory T cells reveals modulators of Foxp3, 2020, Nature

Bluestone's frequent publication venues include:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Cell
  • Nature Immunology

Awards and recognitions received by Bluestone are:

  • AAI Excellence in Mentoring Award, American Association of Immunologists, 2020
  • Distinguished Fellow of the American Association of Immunologists (AAI), 2019
  • Member of the National Academy of Medicine (NAM), 2013
  • Fellow of the American Academy of Arts and Sciences, 2006
  • Fellow of John Simon Guggenheim Memorial Foundation, 1997

Best Publications

  • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

    E A Tivol;F Borriello;A N Schweitzer;W P Lynch

  • CD28/B7 SYSTEM OF T CELL COSTIMULATION

    Deborah J. Lenschow;Theresa L. Walunas;Jeffrey A. Bluestone

  • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

    Weihong Liu;Amy L Putnam;Zhou Xu-yu;Gregory L. Szot

  • CTLA-4 can function as a negative regulator of T cell activation

    Theresa L. Walunas;Deborah J. Lenschow;Christina Y. Bakker;Peter S. Linsley

  • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.

    Benoît Salomon;Deborah J Lenschow;Lesley Rhee;Neda Ashourian

  • International Trial of the Edmonton Protocol for Islet Transplantation

    A. M James Shapiro;Camillo Ricordi;Bernhard J. Hering;Hugh Auchincloss

  • Innate immunity and intestinal microbiota in the development of Type 1 diabetes

    Li Wen;Ruth E. Ley;Ruth E. Ley;Pavel Yu. Volchkov;Peter B. Stranges

  • Identification of a monoclonal antibody specific for a murine T3 polypeptide

    Oberdan Leo;Michele Foo;David H. Sachs;Lawrence E. Samelson

  • Natural versus adaptive regulatory T cells.

    Jeffrey A. Bluestone;Abul K. Abbas

  • The B7 and CD28 receptor families

    Carl H. June;Jeffrey A. Bluestone;Lee M. Nadler;Craig B. Thompson

  • Genetics, pathogenesis and clinical interventions in type 1 diabetes

    Jeffrey A. Bluestone;Kevan Herold;George Eisenbarth

  • Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

    Xuyu Zhou;Samantha L Bailey-Bucktrout;Lukas T Jeker;Cristina Penaranda

  • Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

    DJ Lenschow;Y Zeng;Thistlethwaite;A Montag

  • In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes

    Qizhi Tang;Kammi J. Henriksen;Mingying Bi;Erik B. Finger

  • Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

    Kevan C. Herold;William Hagopian;Julie A. Auger;Ena Poumian-Ruiz

  • Complexities of CD28/B7: CTLA-4 Costimulatory Pathways in Autoimmunity and Transplantation

    Benoît Salomon;Jeffrey A. Bluestone

  • THE NOD MOUSE: A Model of Immune Dysregulation

    Mark S. Anderson;Jeffrey A. Bluestone

  • Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

    Noriko Komatsu;Kazuo Okamoto;Shinichiro Sawa;Tomoki Nakashima

  • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation.

    Qizhi Tang;Jeffrey A Bluestone

  • Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

    Brian T. Fife;Jeffrey A. Bluestone

Frequent Co-Authors

Qizhi Tang
Qizhi Tang University of California, San Francisco
Kevan C. Herold
Kevan C. Herold Yale University
David H. Sachs
David H. Sachs Columbia University
Anne I. Sperling
Anne I. Sperling University of Virginia
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Maria-Luisa Alegre
Maria-Luisa Alegre University of Chicago
Todd M. Brusko
Todd M. Brusko University of Florida
Stephen D. Miller
Stephen D. Miller Northwestern University
Alexander Marson
Alexander Marson University of California, San Francisco

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