D-Index & Metrics Best Publications
Laurence J. Marton

Laurence J. Marton

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 12,452 231 World Ranking 7893 National Ranking 3601

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Gene
  • DNA

Her scientific interests lie mostly in Polyamine, Biochemistry, Spermine, Putrescine and Spermidine. Her research in Polyamine intersects with topics in Polyamine homeostasis, Endocrinology, Polyamine Analogue, Internal medicine and Ornithine decarboxylase. Laurence J. Marton interconnects Cell culture and Biophysics in the investigation of issues within Biochemistry.

Her studies deal with areas such as Thermophile, DNA condensation, Stereochemistry and DNA as well as Spermine. The study incorporates disciplines such as Cell cycle, Binding site, Molecular biology and Inward-rectifier potassium ion channel in addition to Putrescine. Her Spermidine study combines topics in areas such as In vitro, Nucleic acid, Metabolism, Z-DNA and A-DNA.

Her most cited work include:

  • Polyamines as Targets for Therapeutic Intervention (595 citations)
  • Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases (542 citations)
  • Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia (484 citations)

What are the main themes of her work throughout her whole career to date?

Laurence J. Marton mainly focuses on Polyamine, Biochemistry, Spermine, Spermidine and Putrescine. Her Polyamine research integrates issues from Cell growth, Molecular biology, Intracellular, Ornithine decarboxylase and Cytotoxicity. The Biochemistry study combines topics in areas such as Cell culture and Cancer.

Her Spermine research includes elements of Cell biology, Growth inhibition, Binding site and Stereochemistry. Her Spermidine research is multidisciplinary, incorporating elements of Internal medicine, Urine and Endocrinology. Her Putrescine research incorporates elements of Cerebrospinal fluid, Pathology, Ornithine Decarboxylase Inhibitor, DNA synthesis and Chromatography.

She most often published in these fields:

  • Polyamine (57.85%)
  • Biochemistry (37.60%)
  • Spermine (30.17%)

What were the highlights of her more recent work (between 2005-2021)?

  • Polyamine (57.85%)
  • Biochemistry (37.60%)
  • Cancer research (14.46%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Polyamine, Biochemistry, Cancer research, Spermine and Cancer. Her work deals with themes such as In vitro, Polyamine Analogue, Polyamine binding, Pharmacology and In vivo, which intersect with Polyamine. Her study looks at the relationship between Biochemistry and fields such as Nanocarriers, as well as how they intersect with chemical problems.

Her research in Cancer research intersects with topics in Endocrinology, Acute promyelocytic leukemia, Apoptosis, Immunology and Molecular biology. The concepts of her Spermine study are interwoven with issues in Putrescine, Cell biology, Spermidine, Cell cycle and Inward-rectifier potassium ion channel. Her work in Cancer covers topics such as Cell which are related to areas like Gene and Lung cancer.

Between 2005 and 2021, her most popular works were:

  • Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases (542 citations)
  • Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia (484 citations)
  • Subtype and pathway specific responses to anticancer compounds in breast cancer. (360 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Cancer

Laurence J. Marton spends much of her time researching Cancer research, Polyamine, Biochemistry, Cancer and Regulation of gene expression. Her study on Cancer research also encompasses disciplines like

  • In vivo which intersects with area such as Retinoic acid, Myeloid leukemia, Acute promyelocytic leukemia and Pathogenesis,
  • Drug response, Cell and In vitro most often made with reference to Cell culture. Her research integrates issues of Spermine, Polyamine Analogue, Ornithine decarboxylase, Cytotoxicity and Cell cycle in her study of Polyamine.

Laurence J. Marton has researched Spermine in several fields, including Putrescine, Stereochemistry and Cell biology. Her Polyamine Analogue research is classified as research in Spermidine. Her Cancer study combines topics in areas such as Proteasome inhibitor, Apoptosis and Cell growth.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Polyamines as Targets for Therapeutic Intervention

L J Marton;A E Pegg.
Annual Review of Pharmacology and Toxicology (1995)

931 Citations

Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

Robert A. Casero;Laurence J. Marton.
Nature Reviews Drug Discovery (2007)

836 Citations

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Tino Schenk;Weihsu Claire Chen;Stefanie Göllner;Louise Howell.
Nature Medicine (2012)

632 Citations

Subtype and pathway specific responses to anticancer compounds in breast cancer.

Laura M. Heiser;Anguraj Sadanandam;Wen-Lin Kuo;Stephen C. Benz.
Proceedings of the National Academy of Sciences of the United States of America (2012)

491 Citations

Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats.

Gordon D. Lux;Laurence J. Marton;Stephen B. Baylin.
Science (1980)

483 Citations

Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue.

Pokar M. Kabra;Hsian K. Lee;Warren P. Lubich;Laurence J. Marton.
Journal of Chromatography A (1986)

347 Citations

Implications and concepts of polyamine-nucleic acid interactions.

Burt G. Feuerstein;Loren D. Williams;Hirak S. Basu;Laurence J. Marton.
Journal of Cellular Biochemistry (1991)

247 Citations

Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

Yi Huang;Tracy Murray Stewart;Yu Wu;Stephen B. Baylin.
Clinical Cancer Research (2009)

236 Citations

Induction of DNA Topoisomerase II-mediated DNA Cleavage by β-Lapachone and Related Naphthoquinones

Benjamin Frydman;Laurence J. Marton;Jerry S. Sun;Karen Neder.
Cancer Research (1997)

221 Citations

Spermine-DNA interactions: a theoretical study.

Burt G. Feuerstein;Nagarajan Pattabiraman;Laurence J. Marton.
Proceedings of the National Academy of Sciences of the United States of America (1986)

218 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Laurence J. Marton

Robert A. Casero

Robert A. Casero

Johns Hopkins University School of Medicine

Publications: 128

Anthony E. Pegg

Anthony E. Pegg

Pennsylvania State University

Publications: 80

Patrick M. Woster

Patrick M. Woster

Medical University of South Carolina

Publications: 58

Thekkumkat Thomas

Thekkumkat Thomas

Rutgers, The State University of New Jersey

Publications: 48

Joe W. Gray

Joe W. Gray

Oregon Health & Science University

Publications: 42

Jaladanki N. Rao

Jaladanki N. Rao

University of Maryland, Baltimore

Publications: 41

Jian-Ying Wang

Jian-Ying Wang

University of Maryland, Baltimore

Publications: 37

Lan Liu

Lan Liu

University of Maryland, Baltimore

Publications: 35

Tongtong Zou

Tongtong Zou

University of Maryland, Baltimore

Publications: 33

Raymond J. Bergeron

Raymond J. Bergeron

University of Florida

Publications: 32

Nikolaus Seiler

Nikolaus Seiler

Grenoble Alpes University

Publications: 29

Takayoshi Suzuki

Takayoshi Suzuki

Osaka University

Publications: 26

Diane Haddock Russell

Diane Haddock Russell

University of Arizona

Publications: 23

Eugene W. Gerner

Eugene W. Gerner

University of Arizona

Publications: 23

Saverio Minucci

Saverio Minucci

European Institute of Oncology

Publications: 20

Hong-Min Liu

Hong-Min Liu

Zhengzhou University

Publications: 20

Trending Scientists

Xiaodong Li

Xiaodong Li

University of Virginia

Jitendra Padhye

Jitendra Padhye

Microsoft (United States)

Bruce C. Petersen

Bruce C. Petersen

Washington University in St. Louis

Toshiro Hiramoto

Toshiro Hiramoto

University of Tokyo

Harold H. Kung

Harold H. Kung

Northwestern University

Waldemar Adam

Waldemar Adam

University of Würzburg

Jake E. Barralet

Jake E. Barralet

McGill University

Liliana D'Alba

Liliana D'Alba

Ghent University

Kari Ruohonen

Kari Ruohonen

University of Turku

Shohei Mitani

Shohei Mitani

Tokyo Women's Medical University

Mariagrazia Pizza

Mariagrazia Pizza

GlaxoSmithKline (United Kingdom)

Robert A. McCrea

Robert A. McCrea

University of Chicago

Bernhard Odermatt

Bernhard Odermatt

University of Zurich

Carle Paul

Carle Paul

Federal University of Toulouse Midi-Pyrénées

Roger G. Noll

Roger G. Noll

Stanford University

Bruce T. Tsurutani

Bruce T. Tsurutani

California Institute of Technology

Something went wrong. Please try again later.