His primary areas of study are Cancer research, Histone deacetylase, Histone, Cell biology and Transcription factor. His Cancer research research integrates issues from Cancer, Cancer stem cell, Cellular differentiation, Nuclear protein and Epigenetics. He has researched Epigenetics in several fields, including Carcinogenesis and Pharmacology.
His Histone deacetylase study incorporates themes from Molecular biology and Differentiation therapy. The study incorporates disciplines such as Receptor and Leukemia in addition to Histone. The concepts of his Cell biology study are interwoven with issues in DNA damage, Biochemistry, Chromatin, Histone deacetylase inhibitor and Histone deacetylase 2.
His primary scientific interests are in Cancer research, Histone, Histone deacetylase, Cell biology and Epigenetics. His biological study spans a wide range of topics, including Acute promyelocytic leukemia, Promyelocytic leukemia protein, Leukemia and Oncogene. Saverio Minucci interconnects Molecular biology, Acetylation and Pathology in the investigation of issues within Histone.
While the research belongs to areas of Histone deacetylase, Saverio Minucci spends his time largely on the problem of Pharmacology, intersecting his research to questions surrounding In vivo. His Cell biology research focuses on DNA damage and how it relates to DNA repair. His work is dedicated to discovering how Epigenetics, Chromatin are connected with Epigenomics and Chromatin immunoprecipitation and other disciplines.
His scientific interests lie mostly in Cancer research, KDM1A, Demethylase, Histone and Epigenetics. His Cancer research research focuses on Myeloid leukemia in particular. Saverio Minucci focuses mostly in the field of Demethylase, narrowing it down to topics relating to Stereochemistry and, in certain cases, Drug discovery.
His work deals with themes such as Breast cancer, Proteomics and Methylation, which intersect with Histone. His research in Epigenetics intersects with topics in Cancer, Cancer stem cell and Bioinformatics. His PI3K/AKT/mTOR pathway research is multidisciplinary, incorporating perspectives in Autophagy, Kinase and Pharmacology.
Saverio Minucci spends much of his time researching Histone, Cancer research, KDM1A, Immunology and Structure–activity relationship. Saverio Minucci has included themes like Tumor progression, Methylation, Epigenetics and Disease in his Histone study. His studies in Epigenetics integrate themes in fields like Cancer, Cancer therapy, Cancer stem cell, Cell and Gene expression.
His work in Cancer research tackles topics such as Breast cancer which are related to areas like Metastasis. His studies deal with areas such as Acute promyelocytic leukemia, Clonogenic assay and Pharmacology as well as KDM1A. Saverio Minucci works mostly in the field of Immunology, limiting it down to topics relating to Regulation of gene expression and, in certain cases, Myeloid, Cellular differentiation, Ex vivo, Histone deacetylase and Carcinogenesis.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
Saverio Minucci;Saverio Minucci;Pier Giuseppe Pelicci;Pier Giuseppe Pelicci.
Nature Reviews Cancer (2006)
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
Martin Göttlicher;Saverio Minucci;Ping Zhu;Oliver H. Krämer.
The EMBO Journal (2001)
The tripartite motif family identifies cell compartments.
Alexandre Reymond;Germana Meroni;Anna Fantozzi;Giuseppe Merla.
The EMBO Journal (2001)
Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis
Marco Giorgio;Enrica Migliaccio;Francesca Orsini;Demis Paolucci.
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
Emma Langley;Mark Pearson;Mark Pearson;Mario Faretta;Uta Maria Bauer.
The EMBO Journal (2002)
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
Mark Pearson;Roberta Carbone;Carla Sebastiani;Mario Cioce.
Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor
Luciano Di Croce;Veronica A. Raker;Massimo Corsaro;Francesco Fazi.
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
Adrian P. Bracken;Daniela Kleine-Kohlbrecher;Nikolaj Dietrich;Diego Pasini.
Genes & Development (2007)
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