What is he best known for?
The fields of study he is best known for:
Manfred Jung spends much of his time researching Biochemistry, Histone deacetylase, Histone, NAD+ kinase and Histone methyltransferase.
His research in Enzyme, Enzyme inhibitor, Sirtuin, Group III Histone Deacetylases and Docking are components of Biochemistry.
His study focuses on the intersection of Histone deacetylase and fields such as Hydroxamic acid with connections in the field of Growth inhibition and Western blot.
His Histone research focuses on Transcription and how it connects with Zinc, Sirtuin 1 and Protein deacetylase.
The study incorporates disciplines such as Phenotype, Cell, Small molecule and Yeast in addition to NAD+ kinase.
The concepts of his Histone methyltransferase study are interwoven with issues in Cancer, Methyltransferase and Histone methylation.
His most cited work include:
- Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy (325 citations)
- SIRT1 regulates HIV transcription via Tat deacetylation. (264 citations)
- Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy (209 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Biochemistry, Histone, Histone deacetylase, Epigenetics and Cancer research.
Enzyme, NAD+ kinase, Sirtuin, Docking and In vitro are subfields of Biochemistry in which his conducts study.
His Histone research also works with subjects such as
- Acetylation which intersects with area such as HDAC6,
- Cancer which is related to area like Pharmacology.
Histone deacetylase is closely attributed to Hydroxamic acid in his research.
His Epigenetics research includes themes of Computational biology, Drug discovery and Cell biology.
The various areas that he examines in his Cancer research study include Vorinostat, Cell culture, Leukemia and Histone deacetylase inhibitor.
He most often published in these fields:
- Biochemistry (39.94%)
- Histone (23.58%)
- Histone deacetylase (20.44%)
What were the highlights of his more recent work (between 2018-2021)?
- Epigenetics (20.75%)
- Biochemistry (39.94%)
- Cell biology (10.38%)
In recent papers he was focusing on the following fields of study:
His main research concerns Epigenetics, Biochemistry, Cell biology, Combinatorial chemistry and Histone.
His Epigenetics research is multidisciplinary, incorporating elements of Drug action and Cancer research.
His biological study spans a wide range of topics, including Triazole, Moiety and Sirtuin.
His research integrates issues of In vitro, Acetylation, Targeted drug delivery, Derivatization and Photoisomerization in his study of Histone.
His Acetylation study deals with HDAC6 intersecting with Structure–activity relationship, Docking and HDAC8.
As a part of the same scientific study, Manfred Jung usually deals with the Entinostat, concentrating on Albendazole and frequently concerns with Histone deacetylase.
Between 2018 and 2021, his most popular works were:
- Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors (37 citations)
- KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. (21 citations)
- LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML. (21 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Epigenetics, Regulation of gene expression, Cell biology, Biochemistry and Cancer research.
His studies in Epigenetics integrate themes in fields like Autophagy, In vitro, Acetylation, Histone and Drug discovery.
His study in the fields of Histone Demethylases under the domain of Histone overlaps with other disciplines such as Deferasirox.
As a part of the same scientific family, Manfred Jung mostly works in the field of Cell biology, focusing on Methylation and, on occasion, Prostate cancer and Histone H4.
His research in Biochemistry intersects with topics in Drug detection and Phenothiazine.
Manfred Jung interconnects Transcription factor, IRF8 and Conditional gene knockout in the investigation of issues within Cancer research.
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