What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cancer research, Cell biology, Androgen receptor, KDM1A and Molecular biology.
His Cancer research study integrates concerns from other disciplines, such as Histone H3, Histone, Demethylase, Coactivator and Nuclear receptor.
His studies deal with areas such as Syndecan 1, Cadherin, Retinoic acid receptor alpha, Retinoid X receptor and Retinoid X receptor alpha as well as Cell biology.
His biological study focuses on RNF4.
The KDM1A study combines topics in areas such as Progenitor cell, Stem cell and Myeloid leukemia, Immunology.
His research integrates issues of Cranial neural crest and Regulation of gene expression in his study of Molecular biology.
His most cited work include:
- LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. (1383 citations)
- Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. (495 citations)
- Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. (418 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cancer research, Cell biology, Demethylase, Biochemistry and Molecular biology.
The concepts of his Cancer research study are interwoven with issues in Prostate cancer, Androgen receptor, FHL2 and Epigenetics.
His Androgen receptor research includes themes of Coactivator and Nuclear receptor.
His Cell biology course of study focuses on Histone code and Histone demethylation.
Roland Schüle has researched Demethylase in several fields, including Histone H3, Histone methyltransferase and Histone methylation.
His Molecular biology research is multidisciplinary, incorporating perspectives in Enhancer, Histone acetyltransferase, Transcription factor, Transactivation and Promoter.
He most often published in these fields:
- Cancer research (30.92%)
- Cell biology (24.34%)
- Demethylase (22.37%)
What were the highlights of his more recent work (between 2017-2020)?
- Epigenetics (21.05%)
- Cancer research (30.92%)
- Cell biology (24.34%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Epigenetics, Cancer research, Cell biology, Regulation of gene expression and Cell cycle.
The various areas that Roland Schüle examines in his Epigenetics study include Cancer, Receptor and Pharmacology.
His research in Cancer research intersects with topics in Cytotoxic T cell and Breast cancer.
His Epidermis study in the realm of Cell biology interacts with subjects such as GLIS1.
His study on Regulation of gene expression also encompasses disciplines like
- Methylation, which have a strong connection to Effector, Histone code and Histone H4,
- Prostate cancer, Methyllysine and Tudor domain most often made with reference to Chromatin.
His research in Cell cycle focuses on subjects like Histone methyltransferase, which are connected to Drug discovery, HEK 293 cells, Adenocarcinoma and Lung cancer.
Between 2017 and 2020, his most popular works were:
- Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells. (24 citations)
- KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells. (21 citations)
- LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML. (21 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Regulation of gene expression, Cell biology, Chromatin, Methylation and Transcription factor.
His Regulation of gene expression research is multidisciplinary, incorporating elements of Myeloid and Cancer research.
The Stem cell research he does as part of his general Cell biology study is frequently linked to other disciplines of science, such as GLIS1, therefore creating a link between diverse domains of science.
His study in Histone code and Histone lysine methylation are all subfields of Chromatin.
The study incorporates disciplines such as Histone H4, Cell cycle, Prostate cancer and Effector in addition to Methylation.
His Transcription factor study combines topics in areas such as Leukemia, Myeloid leukemia, Epigenetics and Cellular differentiation.
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