World's Best Scientists 2026 revealed!

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Medicine

D-Index
92
Citations
36830
World Ranking
11175
National Ranking
605

Overview

Hubert Serve is affiliated with Goethe University Frankfurt in Germany. Their research primarily encompasses the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a substantial focus on Hematology, Molecular Biology, Genetics, Public Health, Environmental and Occupational Health, and Oncology. Their work spans a broad range of topics centered on leukemia and related hematological conditions.

The main research themes associated with their work include:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Histone Deacetylase Inhibitors Research
  • Multiple Myeloma Research and Treatments
  • Chronic Myeloid Leukemia Treatments
  • Hematopoietic Stem Cell Transplantation

Hubert Serve has contributed to various publication venues, including high-impact journals in hematology and oncology. The frequent venues for their publications are:

  • Blood
  • Annals of Hematology
  • Leukemia
  • HemaSphere
  • Research Square (Research Square)

The scientist has collaborated extensively with several researchers, reflecting a broad network within the hematology research community. Frequent co-authors include:

  • Christoph Röllig
  • Martin Bornhäuser
  • Björn Steffen
  • Uwe Platzbecker
  • Claudia D. Baldus

Some of their recent papers illustrate their focus on acute myeloid leukemia and related treatments. Notable recent publications are:

  • Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN), 2020, Journal of Clinical Oncology
  • CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome, 2021, Blood
  • Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia?, 2020, Blood
  • The proteogenomic subtypes of acute myeloid leukemia, 2022, Cancer Cell
  • A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy, 2020, Leukemia

Best Publications

  • MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer.

    Ping Ji;Sven Diederichs;Wenbing Wang;Sebastian Böing

  • Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

    Richard M. Stone;Sumithra J. Mandrekar;Ben L. Sanford;Kristina Laumann

  • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease.

    Susanne Schnittger;Claudia Schoch;Martin Dugas;Wolfgang Kern

  • Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.

    Masao Mizuki;Regina Fenski;Hartmut Halfter;Itaru Matsumura

  • Ubiquitination and selective autophagy

    S Shaid;C H Brandts;H Serve;I Dikic

  • Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma

    Berno Dankbar;Teresa Padró;Regine Leo;Birgit Feldmann

  • A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease.

    Walter Fiedler;Hubert Serve;Hartmut Döhner;Michael Schwittay

  • Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation (SORMAIN)

    Andreas Burchert;Gesine Bug;Lea V. Fritz;Jürgen Finke

  • Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies.

    Nicola Gökbuget;Michael Kneba;Thorsten Raff;Heiko Trautmann

  • Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation.

    Nicola Gökbuget;Daniel Stanze;Joachim Beck;Helmut Diedrich

  • Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

    Christoph Röllig;Hubert Serve;Andreas Hüttmann;Richard Noppeney

  • Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms.

    Francis H. Grand;Claire E. Hidalgo-Curtis;Thomas Ernst;Katerina Zoi

  • Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure

    Lena Dorsheimer;Birgit Assmus;Tina Rasper;Christina A. Ortmann

  • A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia.

    Walter Fiedler;Rolf Mesters;Heike Tinnefeld;Sonja Loges

  • Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells

    Carsten Müller-Tidow;Björn Steffen;Thomas Cauvet;Lara Tickenbrock

  • Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial

    Hubert Serve;Utz Krug;Ruth Wagner;M. Cristina Sauerland

  • Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

    Chunaram Choudhary;Jesper V. Olsen;Jesper V. Olsen;Christian Brandts;Jürgen Cox

  • Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

    Masao Mizuki;Joachim Schwäble;Joachim Schwäble;Joachim Schwäble;Claudia Steur;Claudia Steur;Claudia Steur;Chunaram Choudhary;Chunaram Choudhary;Chunaram Choudhary

  • Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes

    Utz Krug;Christoph Röllig;Anja Koschmieder;Achim Heinecke

  • Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.

    Uwe Platzbecker;Jan Moritz Middeke;Katja Sockel;Regina Herbst

Frequent Co-Authors

Wolfgang E. Berdel
Wolfgang E. Berdel University of Münster
Carsten Müller-Tidow
Carsten Müller-Tidow University Hospital Heidelberg
Henning Urlaub
Henning Urlaub University of Göttingen
Oliver G. Ottmann
Oliver G. Ottmann Cardiff University
Stefan W. Krause
Stefan W. Krause University of Erlangen-Nuremberg
Hermann Einsele
Hermann Einsele University of Würzburg
Dieter Hoelzer
Dieter Hoelzer Goethe University Frankfurt

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