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Brendan J. Frey

Brendan J. Frey

Award Badge
Computer Science
Canada
2025

D-Index & Metrics

Computer Science

D-Index
71
Citations
44164
World Ranking
1724
National Ranking
62

Research.com Recognitions

  • 2025 - Research.com Computer Science in Canada Leader Award
  • 2023 - Research.com Computer Science in Canada Leader Award
  • 2022 - Research.com Computer Science in Canada Leader Award
  • 2015 - Fellow of the Royal Society of Canada Academy of Science
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Brendan J. Frey is affiliated with the University of Toronto in Canada and works primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Computational Theory and Mathematics, Materials Chemistry, Nutrition and Dietetics, and Biophysics.

The scientist's recent papers include:

  • HiCSR: a Hi-C super-resolution framework for producing highly realistic contact maps, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • A graph neural network approach for molecule carcinogenicity prediction, 2022, Bioinformatics
  • An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • ATP7B variant c.1934T > G p.Met645Arg causes Wilson disease by promoting exon 6 skipping, 2020, npj Genomic Medicine
  • Orthrus: Towards Evolutionary and Functional RNA Foundation Models, 2024, bioRxiv (Cold Spring Harbor Laboratory)

The scientist has coauthored frequently with the following researchers:

  • Leo J. Lee
  • Philip Fradkin
  • Bo Wang
  • Albi Celaj
  • Ken J. Kron

Their work appears often in the following publication venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bioinformatics
  • npj Genomic Medicine
  • UNC Libraries
  • arXiv (Cornell University)

The main topics addressed in their research cover:

  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Computational Drug Discovery Methods
  • Machine Learning in Materials Science
  • Trace Elements in Health
  • Genomics and Chromatin Dynamics

Brendan J. Frey has been recognized by scientific societies through awards such as:

  • Fellow of the Royal Society of Canada, 2015, Academy of Science
  • Fellow of the American Association for the Advancement of Science (AAAS), 2008

Best Publications

  • Factor graphs and the sum-product algorithm

    F.R. Kschischang;B.J. Frey;H.-A. Loeliger

  • Clustering by Passing Messages Between Data Points

    Brendan J. Frey;Delbert Dueck

  • Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning

    Babak Alipanahi;Andrew Delong;Matthew T Weirauch;Brendan J Frey

  • A compendium of RNA-binding motifs for decoding gene regulation

    Debashish Ray;Hilal Kazan;Kate B. Cook;Matthew T. Weirauch;Matthew T. Weirauch

  • The "Wake-Sleep" Algorithm for Unsupervised Neural Networks

    Geoffrey E. Hinton;Peter Dayan;Brendan J. Frey;Radford M. Neal

  • The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

    Nuno L. Barbosa-Morais;Nuno L. Barbosa-Morais;Manuel Irimia;Qun Pan;Hui Y. Xiong

  • Deciphering the splicing code

    Yoseph Barash;John A. Calarco;Weijun Gao;Qun Pan

  • Graphical Models for Machine Learning and Digital Communication

    Brendan J. Frey

  • Deep learning of the tissue-regulated splicing code.

    Michael K. K. Leung;Hui Yuan Xiong;Leo J. Lee;Brendan J. Frey

  • Iterative decoding of compound codes by probability propagation in graphical models

    F.R. Kschischang;B.J. Frey

  • Deep learning in biomedicine.

    Michael Wainberg;Daniele Merico;Andrew Delong;Brendan J Frey

  • Adversarial Autoencoders

    Alireza Makhzani;Jonathon Shlens;Navdeep Jaitly;Ian Goodfellow

  • A Revolution: Belief Propagation in Graphs with Cycles

    Brendan J. Frey;David J. C. MacKay

  • Classifying and segmenting microscopy images with deep multiple instance learning

    Oren Z. Kraus;Jimmy Lei Ba;Brendan J. Frey

  • Non-metric affinity propagation for unsupervised image categorization

    D. Dueck;B.J. Frey

  • C2H2 zinc finger proteins greatly expand the human regulatory lexicon

    Hamed S Najafabadi;Sanie Mnaimneh;Frank W Schmitges;Michael Garton

  • Whole-genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine

    Dimitri J. Stavropoulos;Daniele Merico;Rebekah Jobling;Sarah Bowdin

  • Video Epitomes

    Vincent Cheung;Brendan J. Frey;Nebojsa Jojic

  • The functional landscape of mouse gene expression

    Wen-Wen Zhang;Quaid D. Morris;Richard Chang;Ofer Shai

  • MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

    Hong Han;Manuel Irimia;P. Joel Ross;Hoon Ki Sung

  • Adaptive dropout for training deep neural networks

    Jimmy Ba;Brendan Frey

  • Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform.

    Qun Pan;Ofer Shai;Christine Misquitta;Wen Zhang

Frequent Co-Authors

Nebojsa Jojic
Nebojsa Jojic Microsoft (United States)
Benjamin J. Blencowe
Benjamin J. Blencowe University of Toronto
Quaid Morris
Quaid Morris Memorial Sloan Kettering Cancer Center
Ralf Koetter
Ralf Koetter Technical University of Munich
Thomas S. Huang
Thomas S. Huang University of Illinois at Urbana-Champaign
Daniele Merico
Daniele Merico University of Toronto
Frank R. Kschischang
Frank R. Kschischang University of Toronto
Andrew Emili
Andrew Emili Boston University
Nuno L. Barbosa-Morais
Nuno L. Barbosa-Morais University of Lisbon
Anthony Vetro
Anthony Vetro Mitsubishi Electric (United States)

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