World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
59
Citations
16073
World Ranking
3219
National Ranking
52

Overview

Manuel Irimia is affiliated with Pompeu Fabra University in Spain and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology, Genetics, and Plant Science. Their research spans several related subfields including Cellular and Molecular Neuroscience and Cancer Research.

The scientist's work concentrates on several key topics such as RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, Genomics and Phylogenetic Studies, Genomics and Chromatin Dynamics, Chromosomal and Genetic Variations, and Developmental Biology and Gene Regulation.

Manuel Irimia has published in numerous academic outlets, with frequent publications in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genome biology
  • Molecular Cell
  • Nature Ecology & Evolution
  • Nature Communications

Some of the recent notable papers include:

  • Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals (2021, Genome biology)
  • Best practice standards for circular RNA research (2022, Nature Methods)
  • Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions (2020, Molecular Cell)
  • ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics (2021, Genome biology)
  • Conservative route to genome compaction in a miniature annelid (2020, Nature Ecology & Evolution)

Throughout their career, Manuel Irimia has frequently co-authored with several researchers, including:

  • Federica Mantica
  • Jon Permanyer
  • Sophie Bonnal
  • L. Iñiguez
  • Yamile Márquez

Best Publications

  • A compendium of RNA-binding motifs for decoding gene regulation

    Debashish Ray;Hilal Kazan;Kate B. Cook;Matthew T. Weirauch;Matthew T. Weirauch

  • The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

    Nuno L. Barbosa-Morais;Nuno L. Barbosa-Morais;Manuel Irimia;Qun Pan;Hui Y. Xiong

  • Elephant shark genome provides unique insights into gnathostome evolution

    Byrappa Venkatesh;Byrappa Venkatesh;Alison P. Lee;Vydianathan Ravi;Ashish K. Maurya

  • Widespread intron retention in mammals functionally tunes transcriptomes

    Ulrich Braunschweig;Nuno L. Barbosa-Morais;Nuno L. Barbosa-Morais;Qun Pan;Emil N. Nachman

  • Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

    Neelroop N. Parikshak;Vivek Swarup;T. Grant Belgard;Manuel Irimia

  • A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

    Manuel Irimia;Manuel Irimia;Robert J. Weatheritt;Jonathan D. Ellis;Neelroop N. Parikshak

  • Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

    Jonathan D. Ellis;Miriam Barrios-Rodiles;Recep Çolak;Manuel Irimia

  • Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs.

    Bruce A. Curtis;Goro Tanifuji;Goro Tanifuji;Fabien Burki;Ansgar Gruber;Ansgar Gruber

  • An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.

    Javier Tapial;Javier Tapial;Kevin C.H. Ha;Timothy Sterne-Weiler;André Gohr;André Gohr

  • MBNL proteins repress ES-cell-specific alternative splicing and reprogramming

    Hong Han;Manuel Irimia;P. Joel Ross;Hoon Ki Sung

  • Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling

    Michael John Clarke;Amanda J Lohan;Bernard Liu;Ilias Lagkouvardos

  • 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.

    Tarang Khare;Shraddha Pai;Karolis Koncevicius;Karolis Koncevicius;Mrinal Pal

  • Amphioxus functional genomics and the origins of vertebrate gene regulation

    Ferdinand Marlétaz;Ferdinand Marlétaz;Panos N. Firbas;Ignacio Maeso;Juan J. Tena

  • A Comparative Transcriptomic Analysis Reveals Conserved Features of Stem Cell Pluripotency in Planarians and Mammals

    Roselyne M. Labbé;Roselyne M. Labbé;Manuel Irimia;Ko W. Currie;Alexander Lin

  • Alternative splicing: decoding an expansive regulatory layer

    Manuel Irimia;Benjamin J Blencowe

  • Regulated aggregative multicellularity in a close unicellular relative of metazoa

    Arnau Sebé-Pedrós;Arnau Sebé-Pedrós;Manuel Irimia;Javier del Campo;Helena Parra-Acero

  • Origin of spliceosomal introns and alternative splicing.

    Manuel Irimia;Scott William Roy

  • Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints

    Manuel Irimia;Juan J. Tena;Maria S. Alexis;Ana Fernandez-Miñan

  • Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development

    Mathieu Quesnel-Vallières;Manuel Irimia;Sabine P. Cordes;Sabine P. Cordes;Benjamin J. Blencowe

  • An alternative splicing event amplifies evolutionary differences between vertebrates

    Serge Gueroussov;Thomas Gonatopoulos-Pournatzis;Manuel Irimia;Manuel Irimia;Bushra Raj

Frequent Co-Authors

Scott William Roy
Scott William Roy San Francisco State University
Benjamin J. Blencowe
Benjamin J. Blencowe University of Toronto
Jordi Garcia-Fernàndez
Jordi Garcia-Fernàndez University of Barcelona
José Luis Gómez-Skarmeta
José Luis Gómez-Skarmeta Spanish National Research Council
Iñaki Ruiz-Trillo
Iñaki Ruiz-Trillo Pompeu Fabra University
Boris Lenhard
Boris Lenhard Imperial College London
Nuno L. Barbosa-Morais
Nuno L. Barbosa-Morais University of Lisbon
Ryan Lister
Ryan Lister University of Western Australia
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles

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