World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
62
Citations
15270
World Ranking
10698
National Ranking
334

Overview

Peiyong Jiang is affiliated with the Chinese University of Hong Kong in China. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a particular focus on cancer and prenatal diagnostics.

The scientist has contributed to numerous papers, including recent notable works such as:

  • Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies (2021, Science)
  • Plasma DNA End-Motif Profiling as a Fragmentomic Marker in Cancer, Pregnancy, and Transplantation (2020, Cancer Discovery)
  • Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics (2021, Nature Medicine)
  • Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells (2020, bioRxiv - Cold Spring Harbor Laboratory)
  • Identification and characterization of extrachromosomal circular DNA in maternal plasma (2020, Proceedings of the National Academy of Sciences)

Their research topics cover a breadth of specific areas within the life sciences including:

  • Cancer Genomics and Diagnostics
  • Prenatal Screening and Diagnostics
  • Epigenetics and DNA Methylation
  • Renal and related cancers
  • Single-cell and spatial transcriptomics
  • RNA modifications and cancer
  • Viral-associated cancers and disorders

Peiyong Jiang's main fields of study are Biochemistry, Genetics and Molecular Biology, with 92 publications, followed by Medicine with 65 publications. Within subfields, their work notably encompasses:

  • Molecular Biology
  • Cancer Research
  • Pediatrics, Perinatology and Child Health
  • Oncology
  • Surgery

The scientist's frequent publication venues reflect their disciplinary focus and include:

  • Clinical Chemistry (10 publications)
  • Proceedings of the National Academy of Sciences (6 publications)
  • Genome Research (5 publications)
  • The American Journal of Human Genetics (3 publications)
  • Prenatal Diagnosis (3 publications)

Collaboration is a significant aspect of their research output. Frequent co-authors include:

  • Y. M. Dennis Lo
  • K.C. Allen Chan
  • Rossa W. K. Chiu
  • Suk Hang Cheng
  • W.K. Lam

Best Publications

  • Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus

    Y. M. Dennis Lo;K. C. Allen Chan;Hao Sun;Eric Z. Chen

  • Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

    Kun Sun;Peiyong Jiang;K. C. Allen Chan;John Wong

  • Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

    Peiyong Jiang;Carol W.M. Chan;K. C.Allen Chan;Suk Hang Cheng

  • Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

    K. C.Allen Chan;Peiyong Jiang;Yama W.L. Zheng;Gary J.W. Liao

  • Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

    K. C. Allen Chan;Peiyong Jiang;Carol W. M. Chan;Kun Sun

  • Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing

    Eric Z. Chen;Rossa W. K. Chiu;Hao Sun;Ranjit Akolekar

  • Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies.

    Y. M. Dennis Lo;Diana S. C. Han;Peiyong Jiang;Rossa W. K. Chiu

  • Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

    Stephanie C. Y. Yu;K. C. Allen Chan;Yama W. L. Zheng;Peiyong Jiang

  • The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics.

    Peiyong Jiang;Y.M. Dennis Lo

  • Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

    Pascal Barbry;Christoph Muus;Christoph Muus;Malte Luecken;Gokcen Eraslan

  • Noninvasive prenatal diagnosis of congenital adrenal hyperplasia using cell-free fetal DNA in maternal plasma

    Maria I New;Yu K Tong;Tony Yuen;Peiyong Jiang

  • Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics

    Jason C. H. Tsang;Joaquim S. L. Vong;Lu Ji;Liona C. Y. Poon

  • High-Resolution Profiling of Fetal DNA Clearance from Maternal Plasma by Massively Parallel Sequencing

    Stephanie C.Y. Yu;Shara W.Y. Lee;Peiyong Jiang;Tak Y. Leung

  • Plasma DNA End-Motif Profiling as a Fragmentomic Marker in Cancer, Pregnancy, and Transplantation.

    Peiyong Jiang;Kun Sun;Wenlei Peng;Suk Hang Cheng

  • Noninvasive Prenatal Diagnosis of Monogenic Diseases by Targeted Massively Parallel Sequencing of Maternal Plasma: Application to β-Thalassemia

    Kwan Wood G. Lam;Peiyong Jiang;Gary J.W. Liao;K. C.Allen Chan

  • Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

    Kun Sun;Peiyong Jiang;Suk Hang Cheng;Timothy H.T. Cheng

  • Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma.

    Peiyong Jiang;Kun Sun;Yu K. Tong;Suk Hang Cheng

  • iSeeRNA: identification of long intergenic non-coding RNA transcripts from transcriptome sequencing data.

    Kun Sun;Xiaona Chen;Peiyong Jiang;Xiaofeng Song

  • Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends

    K. C. Allen Chan;Peiyong Jiang;Kun Sun;Yvonne K. Y. Cheng

  • Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts

    Liang Zhou;Lijun Wang;Leina Lu;Peiyong Jiang

Frequent Co-Authors

Rossa W.K. Chiu
Rossa W.K. Chiu Chinese University of Hong Kong
Y.M. Dennis Lo
Y.M. Dennis Lo Chinese University of Hong Kong
Yuk Ming Dennis Lo
Yuk Ming Dennis Lo Chinese University of Hong Kong
Hao Sun
Hao Sun Chinese University of Hong Kong
John Wong
John Wong University of Hong Kong
Stephen L. Chan
Stephen L. Chan Chinese University of Hong Kong
Henry Lik-Yuen Chan
Henry Lik-Yuen Chan Chinese University of Hong Kong
Paul B.S. Lai
Paul B.S. Lai Chinese University of Hong Kong
Vincent Wai-Sun Wong
Vincent Wai-Sun Wong Chinese University of Hong Kong
Wayne Luk
Wayne Luk Imperial College London

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