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Medicine

D-Index
93
Citations
34910
World Ranking
10812
National Ranking
120

Overview

Rossa W.K. Chiu is affiliated with the Chinese University of Hong Kong in China. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology and cancer research.

The scientist's work covers several subfields, including:

  • Molecular Biology
  • Cancer Research
  • Pediatrics, Perinatology and Child Health
  • Infectious Diseases
  • Surgery

Main topics addressed by their research include:

  • Cancer Genomics and Diagnostics
  • Prenatal Screening and Diagnostics
  • Epigenetics and DNA Methylation
  • Renal and related cancers
  • Single-cell and spatial transcriptomics
  • Parvovirus B19 Infection Studies
  • RNA modifications and cancer

Rossa W.K. Chiu has published extensively in several prominent venues. The most frequent publication platforms are:

  • Clinical Chemistry
  • Proceedings of the National Academy of Sciences
  • The American Journal of Human Genetics
  • Prenatal Diagnosis
  • Genome Research

Among the recent papers authored are:

  • Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies, 2021, Science
  • Plasma DNA End-Motif Profiling as a Fragmentomic Marker in Cancer, Pregnancy, and Transplantation, 2020, Cancer Discovery
  • The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB, 2020, The American Journal of Human Genetics
  • Identification and characterization of extrachromosomal circular DNA in maternal plasma, 2020, Proceedings of the National Academy of Sciences
  • Genome-wide detection of cytosine methylation by single molecule real-time sequencing, 2021, Proceedings of the National Academy of Sciences

The scientist collaborates frequently with other researchers, including:

  • Y. M. Dennis Lo
  • Peiyong Jiang
  • K.C. Allen Chan
  • Suk Hang Cheng
  • Rebecca W.Y. Chan

Best Publications

  • Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.

    Rossa W. K. Chiu;K. C. Allen Chan;Yuan Gao;Virginia Y. M. Lau

  • Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus

    Y. M. Dennis Lo;K. C. Allen Chan;Hao Sun;Eric Z. Chen

  • Detection and characterization of placental microRNAs in maternal plasma.

    Stephen S C Chim;Tristan K F Shing;Emily C W Hung;Tak Yeung Leung

  • Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: Large scale validity study

    Rossa W K Chiu;Ranjit Akolekar;Yama W L Zheng;Tak Y Leung

  • Molecular Evolution of the SARS Coronavirus, during the Course of the SARS Epidemic in China

    Jian Feng He;Guo Wen Peng;Jun Min;De Wen Yu

  • Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

    Kun Sun;Peiyong Jiang;K. C. Allen Chan;John Wong

  • Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients.

    Nelson Lee;K.C. Allen Chan;David S. Hui;Enders K.O. Ng

  • Predominant Hematopoietic Origin of Cell-free DNA in Plasma and Serum after Sex-mismatched Bone Marrow Transplantation

    Yanni Y N Lui;Ki Wai Chik;Rossa W K Chiu;Cheong Yip Ho

  • Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

    Peiyong Jiang;Carol W.M. Chan;K. C.Allen Chan;Suk Hang Cheng

  • Analysis of Plasma Epstein-Barr Virus DNA to Screen for Nasopharyngeal Cancer.

    K C Allen Chan;John K S Woo;Ann King;Benny C Y Zee

  • Digital PCR for the molecular detection of fetal chromosomal aneuploidy

    Y. M. Dennis Lo;Fiona M. F. Lun;K. C. Allen Chan;Nancy B. Y. Tsui

  • Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection

    Y M Dennis Lo;Nancy B Y Tsui;Rossa W K Chiu;Tze K Lau

  • Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma.

    Fiona M. F. Lun;Rossa W. K. Chiu;K. C. Allen Chan;Tak Yeung Leung

  • Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

    K. C.Allen Chan;Peiyong Jiang;Yama W.L. Zheng;Gary J.W. Liao

  • mRNA of placental origin is readily detectable in maternal plasma

    Enders K O Ng;Nancy B Y Tsui;Tze K. Lau;Tse N. Leung

  • Effects of Blood-Processing Protocols on Fetal and Total DNA Quantification in Maternal Plasma

    Rossa W. K. Chiu;Leo L. M. Poon;Tze K. Lau;Tse N. Leung

  • Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma

    Fiona M. F. Lun;Nancy B. Y. Tsui;K. C. Allen Chan;Tak Y. Leung

  • Detection of the placental epigenetic signature of the maspin gene in maternal plasma

    Stephen S. C. Chim;Yu K. Tong;Rossa W. K. Chiu;Tze K. Lau

  • Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

    K. C. Allen Chan;Peiyong Jiang;Carol W. M. Chan;Kun Sun

  • Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing

    Eric Z. Chen;Rossa W. K. Chiu;Hao Sun;Ranjit Akolekar

Frequent Co-Authors

Y.M. Dennis Lo
Y.M. Dennis Lo Chinese University of Hong Kong
Yuk Ming Dennis Lo
Yuk Ming Dennis Lo Chinese University of Hong Kong
Peiyong Jiang
Peiyong Jiang Chinese University of Hong Kong
Hao Sun
Hao Sun Chinese University of Hong Kong
Benny Chung-ying Zee
Benny Chung-ying Zee Chinese University of Hong Kong
John Wong
John Wong University of Hong Kong
Kypros H. Nicolaides
Kypros H. Nicolaides King's College London
Paul K.S. Chan
Paul K.S. Chan Chinese University of Hong Kong
Anthony T.C. Chan
Anthony T.C. Chan Chinese University of Hong Kong
Joseph J.Y. Sung
Joseph J.Y. Sung Nanyang Technological University

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