World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
31987
World Ranking
3266
National Ranking
90

Research.com Recognitions

  • 2013 - Fellow, The World Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Yuk Ming Dennis Lo spends much of his time researching Fetus, Prenatal diagnosis, Genetics, Pregnancy and Polymerase chain reaction. The study incorporates disciplines such as Cell, Aneuploidy, RNA, Allele and Physiology in addition to Fetus. His Prenatal diagnosis research includes elements of Genotyping, Non invasive and Obstetrics.

The concepts of his Obstetrics study are interwoven with issues in Amniotic fluid, Rh blood group system and Genotype. He interconnects Immunology and Cord blood in the investigation of issues within Pregnancy. His work in Fetal dna addresses subjects such as DNA, which are connected to disciplines such as Genome.

His most cited work include:

  • Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma. (653 citations)
  • Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing (369 citations)
  • Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments (345 citations)

What are the main themes of his work throughout his whole career to date?

Yuk Ming Dennis Lo mostly deals with DNA, Fetus, Genetics, Nucleic acid and Prenatal diagnosis. His research integrates issues of Cancer, Genome, Computational biology and Molecular biology in his study of DNA. His Fetus research is multidisciplinary, relying on both Aneuploidy and Allele.

His Nucleic acid research incorporates themes from RNA, Reference genome and Genomic sequencing. Yuk Ming Dennis Lo has included themes like Bioinformatics, Trisomy, Genotyping, Digital polymerase chain reaction and Obstetrics in his Prenatal diagnosis study. His research in Pregnancy intersects with topics in Endocrinology, Internal medicine, Immunology and Polymerase chain reaction.

He most often published in these fields:

  • DNA (38.64%)
  • Fetus (35.45%)
  • Genetics (27.73%)

What were the highlights of his more recent work (between 2017-2021)?

  • DNA (38.64%)
  • Computational biology (14.55%)
  • Nucleic acid (21.82%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include DNA, Computational biology, Nucleic acid, Cancer and Sequence. His DNA research is multidisciplinary, incorporating perspectives in Cell-free fetal DNA, Sample, Genome and Fetal dna. His Nucleic acid research includes themes of Organism and Cancer detection.

His Cancer research is multidisciplinary, incorporating elements of Molecular biology and Chromosomal region. Within one scientific family, Yuk Ming Dennis Lo focuses on topics pertaining to Fetus under Allele, and may sometimes address concerns connected to DNA methylation. His work deals with themes such as Ranking, Prenatal diagnosis and Aneuploidy, which intersect with Haplotype.

Between 2017 and 2021, his most popular works were:

  • Plasma Epstein-Barr virus DNA as an archetypal circulating tumour DNA marker (21 citations)
  • Complementary roles of MRI and endoscopic examination in the early detection of nasopharyngeal carcinoma (15 citations)
  • Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells (14 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Yuk Ming Dennis Lo mainly investigates DNA, Plasma dna, Nucleic acid, Serum dna and Fragmentation. The DNA study combines topics in areas such as Genetic marker and Clinical significance. The various areas that Yuk Ming Dennis Lo examines in his Plasma dna study include Fetus, Andrology, Methylation and Gestational age.

His Nucleic acid study integrates concerns from other disciplines, such as Cancer detection and Computational biology. His work carried out in the field of Cancer detection brings together such families of science as Sample, Chromosomal region, Epigenetics and Sequence. His Serum dna study incorporates themes from Chromatin, Biophysics and Sequence.

Best Publications

  • Presence of fetal DNA in maternal plasma and serum

    Y. M. Dennis Lo;Noemi Corbetta;Paul F. Chamberlain;Vik Rai

  • Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: Large scale validity study

    Rossa W K Chiu;Ranjit Akolekar;Yama W L Zheng;Tak Y Leung

  • Molecular Evolution of the SARS Coronavirus, during the Course of the SARS Epidemic in China

    Jian Feng He;Guo Wen Peng;Jun Min;De Wen Yu

  • Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

    Kun Sun;Peiyong Jiang;K. C. Allen Chan;John Wong

  • Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients.

    Nelson Lee;K.C. Allen Chan;David S. Hui;Enders K.O. Ng

  • Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

    K. C.Allen Chan;Peiyong Jiang;Yama W.L. Zheng;Gary J.W. Liao

  • Quantitative and Temporal Correlation between Circulating Cell-Free Epstein-Barr Virus DNA and Tumor Recurrence in Nasopharyngeal Carcinoma

    Y. M. D. Lo;L. Y. S. Chan;A. T. C. Chan;S.-F. Leung

  • Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

    K. C. Allen Chan;Peiyong Jiang;Carol W. M. Chan;Kun Sun

  • Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing

    Eric Z. Chen;Rossa W. K. Chiu;Hao Sun;Ranjit Akolekar

  • Two-way cell traffic between mother and fetus : Biologic and clinical implications

    Y. M. D. Lo;E. S. F. Lo;N. Watson;L. Noakes

  • Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies.

    Y. M. Dennis Lo;Diana S. C. Han;Peiyong Jiang;Rossa W. K. Chiu

  • Plasma Epstein-Barr Viral Deoxyribonucleic Acid Quantitation Complements Tumor-Node-Metastasis Staging Prognostication in Nasopharyngeal Carcinoma

    Sing Fai Leung;Benny Zee;Brigette B. Ma;Edwin P. Hui

  • Increased Maternal Plasma Fetal DNA Concentrations in Women Who Eventually Develop Preeclampsia.

    T. N. Leung;J. Zhang;T. K. Lau;L. Y.S. Chan

  • Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

    Stephanie C. Y. Yu;K. C. Allen Chan;Yama W. L. Zheng;Peiyong Jiang

  • Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA.

    Nancy B. Y. Tsui;Rezan A. Kadir;K. C. Allen Chan;Claudia Chi

  • Kinetics of Plasma Epstein-Barr Virus DNA during Radiation Therapy for Nasopharyngeal Carcinoma

    Y. M. D. Lo;S.-F. Leung;L. Y. S. Chan;A. T. C. Chan

  • Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.

    M. Gidh-Jain;J. Takeda;L. Z. Xu;A. J. Lange

  • Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics

    Jason C. H. Tsang;Joaquim S. L. Vong;Lu Ji;Liona C. Y. Poon

  • Detection of single-copy fetal DNA sequence from maternal blood

    Y. M.D. Lo;P. Patel;M. Sampietro;M. D.G. Gillmer

  • Frequent p15 Promoter Methylation in Tumor and Peripheral Blood from Hepatocellular Carcinoma Patients

    I. H.N. Wong;Yuk-ming Dennis Lo;Winnie Yeo;W. Y. Lau

Frequent Co-Authors

Rossa W.K. Chiu
Rossa W.K. Chiu Chinese University of Hong Kong
Peiyong Jiang
Peiyong Jiang Chinese University of Hong Kong
Benny Chung-ying Zee
Benny Chung-ying Zee Chinese University of Hong Kong
Andrew T. Hattersley
Andrew T. Hattersley University of Exeter
Anthony T.C. Chan
Anthony T.C. Chan Chinese University of Hong Kong
John Wong
John Wong University of Hong Kong
Joseph J.Y. Sung
Joseph J.Y. Sung Nanyang Technological University
Hao Sun
Hao Sun Chinese University of Hong Kong
Paul K.S. Chan
Paul K.S. Chan Chinese University of Hong Kong
John I. Bell
John I. Bell Ellison Institute of Technology

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