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Michael R. Speicher

Michael R. Speicher

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Genetics
Austria
2025

D-Index & Metrics

Genetics

D-Index
87
Citations
38559
World Ranking
1192
National Ranking
3

Research.com Recognitions

  • 2025 - Research.com Genetics in Austria Leader Award
  • 2024 - Research.com Genetics in Austria Leader Award
  • 2023 - Research.com Genetics in Austria Leader Award
  • 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Overview

Michael R. Speicher is affiliated with the Medical University of Graz in Austria. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. The main subfields of study for this scientist include Molecular Biology, Cancer Research, Pathology and Forensic Medicine, Oncology, and Pulmonary and Respiratory Medicine.

Their work frequently covers topics such as Cancer Genomics and Diagnostics, Genetic Factors in Colorectal Cancer, Single-cell and Spatial Transcriptomics, Molecular Biology Techniques and Applications, Lung Cancer Treatments and Mutations, Genomics and Rare Diseases, and Cancer Cells and Metastasis.

Michael R. Speicher has published extensively in various scientific venues, with noted frequent publications in:

  • Cancers
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cancer
  • Journal of Medical Genetics

The scientist has coauthored multiple papers with several colleagues, including:

  • Ellen Heitzer
  • Qing Zhou
  • Samantha O. Hasenleithner
  • Samantha Perakis
  • Gerald Höefler

Recent publications by Michael R. Speicher include:

  • Cell-Free DNA and Apoptosis: How Dead Cells Inform About the Living (2020, Trends in Molecular Medicine)
  • Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity (2020, EMBO Molecular Medicine)
  • A clinician's handbook for using ctDNA throughout the patient journey (2022, Molecular Cancer)
  • Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency (2021, Journal of Medical Genetics)
  • Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling (2020, Cancers)

Michael R. Speicher was awarded membership in the German National Academy of Sciences Leopoldina in 2019 for contributions to Human Genetics and Molecular Medicine.

Best Publications

  • Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

    Gabriela Bindea;Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Marie Tosolini;Marie Tosolini;Marie Tosolini;Amos Kirilovsky;Amos Kirilovsky;Amos Kirilovsky

  • Vogel and Motulsky's Human Genetics: Problems and Approaches

    Friedrich Vogel;Arno G. Motulsky;Michael R. Speicher;Armo G. Motulsky

  • Karyotyping human chromosomes by combinatorial multi-fluor FISH

    M. R. Speicher;S. G. Gwyn Ballard;D. C. Ward

  • Mutations in GNA11 in Uveal Melanoma

    Catherine D Van Raamsdonk;Klaus G Griewank;Michelle B Crosby;Maria C Garrido

  • Current and future perspectives of liquid biopsies in genomics-driven oncology.

    Ellen Heitzer;Imran S Haque;Charles E S Roberts;Michael R Speicher

  • Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

    Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea;Helen K. Angell;Pauline Maby

  • Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes

    Andreas Bolzer;Gregor Kreth;Irina Solovei;Daniela Koehler

  • Germline mutations in BAP1 predispose to melanocytic tumors

    Thomas Wiesner;Anna C Obenauf;Anna C Obenauf;Rajmohan Murali;Isabella Fried

  • A survey of tools for variant analysis of next-generation genome sequencing data

    Stephan Pabinger;Andreas Dander;Maria Fischer;Rene Snajder

  • Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization

    Stanislas du Manoir;Michael R. Speicher;Stefan Joos;Evelin Schröck

  • Role of Chromosome Territories in the Functional Compartmentalization of the Cell Nucleus

    Thomas Cremer;A. Kurz;R. M. Zirbel;S. Dietzel

  • The biology of circulating tumor cells

    K Pantel;M R Speicher

  • Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells

    Christoph A. Klein;Oleg Schmidt-Kittler;Julian A. Schardt;Klaus Pantel

  • The new cytogenetics: blurring the boundaries with molecular biology.

    Michael R. Speicher;Nigel P. Carter

  • Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

    Ellen Heitzer;Martina Auer;Christin Gasch;Martin Pichler

  • Securin is required for chromosomal stability in human cells

    Bert Vogelstein;Kenneth W. Kinzler;Prasad Jallepalli;Christoph Lengauer

  • ArticleSecurin Is Required for Chromosomal Stability in Human Cells

    Prasad V. Jallepalli;Irene C. Waizenegger;Fred Bunz;Sabine Langer

  • The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

    Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea;Amos Kirilovsky;Amos Kirilovsky;Amos Kirilovsky;Helen K. Angell

  • Defining 'chromosomal instability'.

    Jochen B. Geigl;Anna C. Obenauf;Thomas Schwarzbraun;Michael R. Speicher

  • Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing.

    Ellen Heitzer;Peter Ulz;Jelena Belic;Stefan Gutschi

Frequent Co-Authors

Thomas Cremer
Thomas Cremer Ludwig-Maximilians-Universität München
Klaus Pantel
Klaus Pantel Universität Hamburg
Thomas Ried
Thomas Ried National Institutes of Health
Roland Eils
Roland Eils Charité - University Medicine Berlin
Peter Lichter
Peter Lichter German Cancer Research Center
Christoph Bock
Christoph Bock Austrian Academy of Sciences
David C. Ward
David C. Ward Nevada Cancer Research Foundation
Nigel P. Carter
Nigel P. Carter Wellcome Sanger Institute

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