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Genetics

D-Index
77
Citations
21107
World Ranking
1770
National Ranking
131

Overview

Anna Jauch is affiliated with Heidelberg University in Germany. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, with substantial contributions in molecular biology, hematology, oncology, genetics, and cancer research.

The main topics of Anna Jauch's work include:

  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis
  • Cancer Genomics and Diagnostics
  • Cancer Treatment and Pharmacology
  • Single-cell and spatial transcriptomics
  • Acute Myeloid Leukemia Research

Jauch has published extensively in several key scientific venues. Frequent publication venues include:

  • Blood
  • Leukemia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Lymphoma Myeloma & Leukemia
  • European Journal of Nuclear Medicine and Molecular Imaging

Among their recent papers are:

  • Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone for the Treatment of High-Risk Newly Diagnosed Multiple Myeloma, 2023, Journal of Clinical Oncology
  • Daratumumab for systemic AL amyloidosis: prognostic factors and adverse outcome with nephrotic-range albuminuria, 2020, Blood
  • Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia, 2023, Cell Stem Cell
  • Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients, 2021, Haematologica
  • Isatuximab, carfilzomib, lenalidomide, and dexamethasone (Isa-KRd) in front-line treatment of high-risk multiple myeloma: interim analysis of the GMMG-CONCEPT trial, 2021, Leukemia

Jauch's frequent collaborators include:

  • Hartmut Goldschmidt
  • Marc S. Raab
  • Hans Salwender
  • Katja Weisel
  • Britta Besemer

Best Publications

  • Bortezomib Induction and Maintenance Treatment in Patients With Newly Diagnosed Multiple Myeloma: Results of the Randomized Phase III HOVON-65/ GMMG-HD4 Trial

    Pieter Sonneveld;Ingo G.H. Schmidt-Wolf;Bronno Van Der Holt;Laila El Jarari

  • Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

    Stefan Stein;Marion G. Ott;Stephan Schultze-Strasser;Anna Jauch

  • Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

    Dagmar Walter;Amelie Lier;Anja Geiselhart;Frederic B. Thalheimer

  • Role of Chromosome Territories in the Functional Compartmentalization of the Cell Nucleus

    Thomas Cremer;A. Kurz;R. M. Zirbel;S. Dietzel

  • Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

    Sandie Tuduri;Sandie Tuduri;Laure Crabbé;Chiara Conti;Hélène Tourrière

  • The Genomic and Transcriptomic Landscape of a HeLa Cell Line

    Jonathan J M Landry;Paul Theodor Pyl;Tobias Rausch;Thomas Zichner

  • DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2.

    Agata Smogorzewska;Jan Karlseder;Heidi Holtgreve-Grez;Anna Jauch

  • Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p

    Kai Neben;Henk M. Lokhorst;Anna Jauch;Uta Bertsch

  • Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

    Annemiek Broyl;Dirk Hose;Henk Lokhorst;Yvonne de Knegt

  • Autophagic cell death restricts chromosomal instability during replicative crisis.

    Joe Nassour;Robert Radford;Adriana Correia;Javier Miralles Fusté

  • Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor

    Kurt Schönfeld;Christiane Sahm;Congcong Zhang;Sonja Naundorf

  • Reconstruction of genomic rearrangements in great apes and gibbons by chromosome painting.

    Anna Jauch;Johannes Wienberg;Roscoe Stanyon;N. Arnold

  • The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature

    Jérôme Moreaux;Friedrich W. Cremer;Friedrich W. Cremer;Thierry Reme;Thierry Reme;Marc Raab;Marc Raab

  • An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

    Milena Traykova-Brauch;Kai Schönig;Oliver Greiner;Tewfik Miloud

  • Telomere dysfunction as a cause of genomic instability in Werner syndrome

    Laure Crabbe;Anna Jauch;Colleen M. Naeger;Heidi Holtgreve-Grez

  • Progression in Smoldering Myeloma Is Independently Determined by the Chromosomal Abnormalities del(17p), t(4;14), Gain 1q, Hyperdiploidy, and Tumor Load

    Kai Neben;Anna Jauch;Thomas Hielscher;Jens Hillengass

  • Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization

    Johannes Wienberg;Anna Jauch;Roscoe Stanyon;Thomas Cremer

  • Translocation t(11;14) Is Associated With Adverse Outcome in Patients With Newly Diagnosed AL Amyloidosis When Treated With Bortezomib-Based Regimens

    Tilmann Bochtler;Ute Hegenbart;Christina Kunz;Martin Granzow

  • Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

    K. Martin Kortüm;Elias K. Mai;Nur H. Hanafiah;Chang Xi Shi

  • Homologies in human and Macaca fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries.

    Johannes Wienberg;Roscoe Stanyon;Anna Jauch;Thomas Cremer

Frequent Co-Authors

Hartmut Goldschmidt
Hartmut Goldschmidt University Hospital Heidelberg
Axel Benner
Axel Benner German Cancer Research Center
Anthony D. Ho
Anthony D. Ho University Hospital Heidelberg
Thierry Rème
Thierry Rème Grenoble Alpes University
Claus R. Bartram
Claus R. Bartram Heidelberg University
Ingo G.H. Schmidt-Wolf
Ingo G.H. Schmidt-Wolf University Hospital Bonn
Peter Brossart
Peter Brossart University Hospital Bonn
Pieter Sonneveld
Pieter Sonneveld Erasmus University Rotterdam
Carsten Müller-Tidow
Carsten Müller-Tidow University Hospital Heidelberg
Thomas Cremer
Thomas Cremer Ludwig-Maximilians-Universität München

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