D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 60 Citations 10,998 259 World Ranking 2370 National Ranking 163

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Axel Schambach spends much of his time researching Cell biology, Genetic enhancement, Immunology, Vector and Viral vector. His Cell biology research includes elements of Transcription factor and Cellular differentiation. His work deals with themes such as Transgene, Bioinformatics, Pathology, Wiskott–Aldrich syndrome and Gene targeting, which intersect with Genetic enhancement.

His studies deal with areas such as Cancer research, Severe combined immunodeficiency and Transplantation as well as Immunology. His Vector research incorporates elements of Insertional mutagenesis, Epigenetics and Long terminal repeat. His study looks at the relationship between Viral vector and fields such as Molecular biology, as well as how they intersect with chemical problems.

His most cited work include:

  • Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity (334 citations)
  • Skin tissue generation by laser cell printing. (315 citations)
  • Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors (310 citations)

What are the main themes of his work throughout his whole career to date?

Axel Schambach mainly investigates Cell biology, Genetic enhancement, Haematopoiesis, Viral vector and Cancer research. His Cell biology research incorporates themes from Cellular differentiation, Transcription factor, Molecular biology, Induced pluripotent stem cell and Transduction. His Genetic enhancement study combines topics from a wide range of disciplines, such as Vector, Transgene, Transplantation and Virology.

His Vector research includes themes of Insertional mutagenesis and Long terminal repeat. In his study, which falls under the umbrella issue of Haematopoiesis, Interleukin 12 is strongly linked to Immunology. Axel Schambach has included themes like Cell, Chimeric antigen receptor, Immunotherapy and Bone marrow in his Cancer research study.

He most often published in these fields:

  • Cell biology (47.63%)
  • Genetic enhancement (38.15%)
  • Haematopoiesis (35.99%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (31.03%)
  • Genetic enhancement (38.15%)
  • Cell biology (47.63%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Genetic enhancement, Cell biology, Haematopoiesis and Progenitor cell. The study incorporates disciplines such as Cell, T cell, Chimeric antigen receptor, Immune system and Antigen in addition to Cancer research. His Genetic enhancement research integrates issues from CD34, Clinical trial, Viral vector and Disease.

Axel Schambach combines subjects such as Severe combined immunodeficiency and Immunology with his study of Viral vector. His Cell biology study combines topics in areas such as Embryonic stem cell, Induced pluripotent stem cell and DNA methylation. His Haematopoiesis study is related to the wider topic of Stem cell.

Between 2018 and 2021, his most popular works were:

  • High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia. (19 citations)
  • High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia. (19 citations)
  • Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application (19 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Axel Schambach mostly deals with Cancer research, Chimeric antigen receptor, Cell biology, Viral vector and Genetic enhancement. In Cancer research, Axel Schambach works on issues like Transduction, which are connected to Reporter gene and Haematopoiesis. His Chimeric antigen receptor study integrates concerns from other disciplines, such as Cytotoxic T cell, Natural killer cell and Hematopoietic stem cell.

His Cell biology research is multidisciplinary, incorporating perspectives in Transgene, Cytokine and Induced pluripotent stem cell. The Viral vector study combines topics in areas such as Tumor microenvironment and CD34, Stem cell. Axel Schambach studies Gene delivery, a branch of Genetic enhancement.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity

Christian Jörg Braun;Kaan Boztug;Anna Paruzynski;Maximilian Witzel.
Science Translational Medicine (2014)

437 Citations

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

Ute Modlich;Susana Navarro;Daniela Zychlinski;Tobias Maetzig.
Molecular Therapy (2009)

396 Citations

Skin tissue generation by laser cell printing.

Lothar Koch;Andrea Deiwick;Sabrina Schlie;Stefanie Michael.
Biotechnology and Bioengineering (2012)

380 Citations

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

Ute Modlich;Jens Bohne;Manfred Schmidt;Christof von Kalle.
Blood (2006)

362 Citations

A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

Salima Hacein-Bey-Abina;Sung Yun Pai;H. Bobby Gaspar;Myriam Armant.
The New England Journal of Medicine (2014)

350 Citations

A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.

Jianwei Wang;Qian Sun;Yohei Morita;Hong Jiang.
Cell (2012)

321 Citations

Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors

Daniela Zychlinski;Axel Schambach;Ute Modlich;Tobias Maetzig.
Molecular Therapy (2008)

312 Citations

Long noncoding RNA Chast promotes cardiac remodeling.

Janika Viereck;Regalla Kumarswamy;Ariana Foinquinos;Ke Xiao.
Science Translational Medicine (2016)

268 Citations

The phenotype of human STK4 deficiency

Hengameh Abdollahpour;Giridharan Appaswamy;Daniel Kotlarz;Daniel Kotlarz;Jana Diestelhorst;Jana Diestelhorst.
Blood (2011)

266 Citations

Gene therapy on the move

Kerstin B. Kaufmann;Hildegard Büning;Anne Galy;Axel Schambach;Axel Schambach.
Embo Molecular Medicine (2013)

253 Citations

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