Manfred Schmidt

Overview

Best Publications

• LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

  S. Hacein-Bey-Abina;C. Von Kalle;C. Von Kalle;M. Schmidt;M. P. McCormack

  4518
  Citations

• A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency

  Salima Hacein-Bey-Abina;Christof Von Kalle;Manfred Schmidt;Françoise Le Deist

  2417
  Citations

• Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

  Nathalie Cartier;Salima Hacein-Bey-Abina;Cynthia C. Bartholomae;Gabor Veres

  1787
  Citations

• Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

  Steven J. Howe;Marc R. Mansour;Kerstin Schwarzwaelder;Cynthia Bartholomae

  1507
  Citations

• Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

  Alessandra Biffi;Eugenio Montini;Laura Lorioli;Martina Cesani

  1400
  Citations

• Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

  Marion G Ott;Manfred Schmidt;Kerstin Schwarzwaelder;Stefan Stein

  1391
  Citations

• Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

  Alessandro Aiuti;Luca Biasco;Samantha Scaramuzza;Francesca Ferrua

  1231
  Citations

• Dissecting the genomic complexity underlying medulloblastoma

  David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner

  930
  Citations

• Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

  Stefan Stein;Marion G. Ott;Stephan Schultze-Strasser;Anna Jauch

  913
  Citations

• Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

  Eugenio Montini;Daniela Cesana;Manfred Schmidt;Francesca Sanvito

  873
  Citations

• Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

  H Bobby Gaspar;Kathryn L Parsley;Steven Howe;Doug King

  825
  Citations

• Murine leukemia induced by retroviral gene marking.

  Zhixiong Li;Zhixiong Li;Jochen Düllmann;Bernd Schiedlmeier;Manfred Schmidt

  818
  Citations

• An unbiased genome-wide analysis of zinc-finger nuclease specificity

  Richard Gabriel;Angelo Lombardo;Anne Arens;Jeffrey C Miller

  676
  Citations

• The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy.

  Eugenio Montini;Daniela Cesana;Manfred Schmidt;Francesca Sanvito

  649
  Citations

• Stem-Cell Gene Therapy for the Wiskott–Aldrich Syndrome

  Kaan Boztug;Manfred Schmidt;Adrian Schwarzer;Pinaki P. Banerjee

  643
  Citations

• Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity

  Christian Jörg Braun;Kaan Boztug;Anna Paruzynski;Maximilian Witzel

  630
  Citations

• Effective gene therapy with nonintegrating lentiviral vectors

  Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Rafael J Yáñez-Muñoz;Kamaljit S Balaggan;Angus MacNeil;Steven J Howe

  579
  Citations

• High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

  Manfred Schmidt;Kerstin Schwarzwaelder;Cynthia Bartholomae;Karim Zaoui

  451
  Citations

• Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

  Joachim Weischenfeldt;Ronald Simon;Lars Feuerbach;Karin Schlangen

  381
  Citations

• Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

  Sebastian M. Dieter;Claudia R. Ball;Christopher M. Hoffmann;Ali Nowrouzi

  356
  Citations