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Shigaku Ikeda

Shigaku Ikeda

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10488
World Ranking
13955
National Ranking
980

Overview

Shigaku Ikeda is affiliated with Juntendo University in Japan and has a research portfolio primarily centered around Medicine, with significant contributions to Biochemistry, Genetics and Molecular Biology. Their scholarly work spans several subfields including Dermatology, Immunology, Epidemiology, Cell Biology, and Molecular Biology.

Their research topics cover a range of areas focused on skin health and immune responses. These include Dermatology and Skin Diseases, Wound Healing and Treatments, Antimicrobial Peptides and Activities, Asthma and Respiratory Diseases, Nail Diseases and Treatments, Autoimmune Bullous Skin Diseases, and Allergic Rhinitis and Sensitization.

Frequent co-authors collaborating with Shigaku Ikeda are:

  • Hideoki Ogawa
  • Ko Okumura
  • François Niyonsaba
  • Ge Peng
  • Takasuke Ogawa

The scientist regularly publishes in the following venues:

  • Journal of Investigative Dermatology
  • The Nishinihon Journal of Dermatology
  • Medical Mycology Journal
  • Annals of Dermatology
  • The Journal of Dermatology

Some notable recent papers authored or co-authored by Shigaku Ikeda include:

  • "Role of Antimicrobial Peptides in Skin Barrier Repair in Individuals with Atopic Dermatitis," published in 2020 in International Journal of Molecular Sciences
  • "The Antimicrobial Peptide Human β-Defensin-3 Accelerates Wound Healing by Promoting Angiogenesis, Cell Migration, and Proliferation Through the FGFR/JAK2/STAT3 Signaling Pathway," published in 2021 in Frontiers in Immunology
  • "Human β-defensin-3 attenuates atopic dermatitis-like inflammation through autophagy activation and the aryl hydrocarbon receptor signaling pathway," published in 2022 in Journal of Clinical Investigation
  • "The Japanese Society for Apheresis clinical practice guideline for therapeutic apheresis," published in 2021 in Therapeutic Apheresis and Dialysis
  • "Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss," published in 2020 in EBioMedicine

Best Publications

  • Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease

    Zhilan Hu;Jeannette M. Bonifas;Jenna Beech;Graham Bench

  • Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

    Tomomitsu Hirota;Atsushi Takahashi;Michiaki Kubo;Tatsuhiko Tsunoda

  • A randomized double-blind trial of intravenous immunoglobulin for pemphigus

    Masayuki Amagai;Shigaku Ikeda;Hiroshi Shimizu;Hajime Iizuka

  • Synergistic effect of antibacterial agents human β-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli

    Xuejun Chen;François Niyonsaba;Hiroko Ushio;Daiju Okuda

  • Cathelicidin LL‐37 induces the generation of reactive oxygen species and release of human α‐defensins from neutrophils

    Y. Zheng;F. Niyonsaba;H. Ushio;I. Nagaoka

  • Antimicrobial peptides human β‐defensin (hBD)‐3 and hBD‐4 activate mast cells and increase skin vascular permeability

    Xuejun Chen;François Niyonsaba;Hiroko Ushio;Mutsuko Hara

  • Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2–Toll-like receptor 6 pathway

    Anh Tuan Vu;Tadashi Baba;Xue Chen;Xue Chen;Tuan Anh Le

  • Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP

    Hideki Fujita;Tadashi Terui;Koremasa Hayama;Masashi Akiyama

  • The extra domain A of fibronectin stimulates murine mast cells via Toll-like receptor 4

    Srie Prihianti Gondokaryono;Hiroko Ushio;François Niyonsaba;Mutsuko Hara

  • Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases.

    Toshiro Takai;Shigaku Ikeda

  • Therapeutic guidelines for the treatment of generalized pustular psoriasis (GPP) based on a proposed classification of disease severity

    Y Umezawa;A Ozawa;T Kawasima;H Shimizu

  • Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.

    Hirokazu Kinoshita;Toshiro Takai;Tuan Anh Le;Seiji Kamijo

  • Clinical trial of a laser device called fractional photothermolysis system for acne scars.

    Toshio Hasegawa;Tomoyuki Matsukura;Yuki Mizuno;Yasushi Suga

  • Mite serine protease activates protease‐activated receptor‐2 and induces cytokine release in human keratinocytes

    T. Kato;T. Takai;T. Fujimura;H. Matsuoka

  • Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses

    Yuko Kikuchi;Toshiro Takai;Takatoshi Kuhara;Mikiko Ota

  • Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis

    Shigaku Ikeda;Hidetoshi Takahashi;Yasushi Suga;Hikaru Eto

  • Cytokine secretion profiles of human keratinocytes during Trichophyton tonsurans and Arthroderma benhamiae infections

    Yumi Shiraki;Yoshio Ishibashi;Masataro Hiruma;Akemi Nishikawa

  • Host Defense (Antimicrobial) Peptide, Human β-Defensin-3, Improves the Function of the Epithelial Tight-Junction Barrier in Human Keratinocytes

    Chanisa Kiatsurayanon;François Niyonsaba;Rithee Smithrithee;Toshihiro Akiyama

  • Reduction of Skin Barrier Function by Proteolytic Activity of a Recombinant House Dust Mite Major Allergen Der f 1

    Toshinobu Nakamura;Yusuke Hirasawa;Toshiro Takai;Kouich Mitsuishi

  • Staphylococcus aureus Extracellular Protease Causes Epidermal Barrier Dysfunction

    Yusuke Hirasawa;Toshiro Takai;Toshinobu Nakamura;Kouichi Mitsuishi

Frequent Co-Authors

Hideoki Ogawa
Hideoki Ogawa Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Susumu Nakae
Susumu Nakae Hiroshima University
Keiji Iwatsuki
Keiji Iwatsuki Okayama University
Takashi Hashimoto
Takashi Hashimoto Osaka Metropolitan University
Takashi Sugita
Takashi Sugita Meiji Pharmaceutical University
Hidetoshi Inoko
Hidetoshi Inoko Tokai University
Hirohisa Saito
Hirohisa Saito Juntendo University
Masayuki Amagai
Masayuki Amagai Keio University
Isao Nagaoka
Isao Nagaoka Juntendo University

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