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Hirohisa Saito

Hirohisa Saito

D-Index & Metrics

Immunology

D-Index
99
Citations
32024
World Ranking
761
National Ranking
26

Medicine

D-Index
99
Citations
32102
World Ranking
8671
National Ranking
228

Overview

Hirohisa Saito is affiliated with Juntendo University in Japan and has contributed extensively to research in the field of Medicine, with a particular focus on Immunology and Allergy. Their scholarly work encompasses main fields such as Immunology, Immunology and Allergy, Physiology, Surgery, and Dermatology, demonstrating a broad engagement with medical science.

Their research topics cover areas including Asthma and respiratory diseases, IL-33, ST2, and ILC pathways, Eosinophilic Esophagitis, Food Allergy and Anaphylaxis Research, Allergic Rhinitis and Sensitization, Dermatology and Skin Diseases, and Contact Dermatitis and Allergies.

Some of their recent papers include:

  • Enhanced early skin treatment for atopic dermatitis in infants reduces food allergy, 2023, Journal of Allergy and Clinical Immunology
  • Laundry detergents and surfactants-induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s, 2023, Allergy
  • STAT6 gain-of-function variant exacerbates multiple allergic symptoms, 2022, Journal of Allergy and Clinical Immunology
  • Does asthma affect morbidity or severity of COVID-19?, 2020, Journal of Allergy and Clinical Immunology
  • Comparison of Nonesophageal Eosinophilic Gastrointestinal Disorders with Eosinophilic Esophagitis: A Nationwide Survey, 2021, The Journal of Allergy and Clinical Immunology In Practice

Frequent coauthors who have collaborated extensively with Saito include:

  • Kenji Matsumoto
  • Hideaki Morita
  • Zuhair K. Ballas
  • Iowa Deputy
  • David Huston

Their research has been published mainly in notable journals such as:

  • Journal of Allergy and Clinical Immunology
  • Allergology International
  • Allergy
  • PubMed
  • The Journal of Allergy and Clinical Immunology In Practice

Throughout their career, Saito has contributed to a wide range of topics related to immunological responses and allergic conditions, particularly focusing on pathways involving IL-33 and innate lymphoid cells (ILC2s). Their work addresses both clinical and physiological aspects of allergic diseases and respiratory conditions.

Best Publications

  • Rationale and study design of the Japan environment and children’s study (JECS)

    Toshihiro Kawamoto;Toshihiro Kawamoto;Hiroshi Nitta;Katsuyuki Murata;Eisaku Toda

  • IL-33 is a crucial amplifier of innate rather than acquired immunity

    Keisuke Oboki;Tatsukuni Ohno;Naoki Kajiwara;Ken Arae

  • Application of moisturizer to neonates prevents development of atopic dermatitis

    Kenta Horimukai;Kumiko Morita;Masami Narita;Mai Kondo

  • Mast cells as sources of cytokines, chemokines, and growth factors.

    Kaori Mukai;Mindy Tsai;Hirohisa Saito;Stephen J. Galli

  • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells

    Ajithkumar Vasanthakumar;Kazuyo Moro;Annie Xin;Yang Liao

  • SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses

    Yoh Ichi Seki;Hiromasa Inoue;Naoko Nagata;Katsuhiko Hayashi

  • Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.

    M. Streuli;N. X. Krueger;Tran Thai;May Tang

  • IL-33 can promote survival, adhesion and cytokine production in human mast cells.

    Motoyasu Iikura;Hajime Suto;Hajime Suto;Naoki Kajiwara;Keisuke Oboki

  • Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, placebo-controlled trial.

    Osamu Natsume;Shigenori Kabashima;Junko Nakazato;Kiwako Yamamoto-Hanada

  • Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

    M Streuli;L R Hall;Y Saga;S F Schlossman

  • Th17 and allergy.

    Keisuke Oboki;Tatsukuni Ohno;Hirohisa Saito;Susumu Nakae;Susumu Nakae

  • Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins.

    Hirohisa Saito;Kiyohiko Hatake;Ann M. Dvorak;Kristin M. Leiferman

  • A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

    M Streuli;N X Krueger;L R Hall;S F Schlossman

  • IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcεRI signals

    Lien H. Ho;Tatsukuni Ohno;Keisuke Oboki;Naoki Kajiwara

  • Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells.

    H Saito;M Ebisawa;H Tachimoto;M Shichijo

  • Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.

    Masafumi Horie;Ichiro Sekiya;Takeshi Muneta;Shizuko Ichinose

  • Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

    François Niyonsaba;Hiroko Ushio;Mutsuko Hara;Hidenori Yokoi

  • IL-33 Mediates Inflammatory Responses in Human Lung Tissue Cells

    Akiko Yagami;Kanami Orihara;Hideaki Morita;Kyoko Futamura

  • An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation By Promoting Regulatory T Cell Numbers

    Hideaki Morita;Ken Arae;Hirotoshi Unno;Kousuke Miyauchi

  • Thymic Stromal Lymphopoietin Gene Promoter Polymorphisms Are Associated with Susceptibility to Bronchial Asthma

    Michishige Harada;Tomomitsu Hirota;Aya I. Jodo;Yuki Hitomi

Frequent Co-Authors

Kenji Matsumoto
Kenji Matsumoto Izumi Municipal Hospital
Susumu Nakae
Susumu Nakae Hiroshima University
Yukihiro Ohya
Yukihiro Ohya National Center For Child Health and Development
Yoshimichi Okayama
Yoshimichi Okayama Nihon University
Motohiro Ebisawa
Motohiro Ebisawa Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Kazuo Tsubota
Kazuo Tsubota Keio University
Akira Matsuda
Akira Matsuda Juntendo University
Gozoh Tsujimoto
Gozoh Tsujimoto Kyoto University
Hideoki Ogawa
Hideoki Ogawa Juntendo University

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