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Timothy N. C. Wells

Timothy N. C. Wells

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
23835
World Ranking
3896
National Ranking
288

Overview

Timothy N. C. Wells is affiliated with Cardiff University in the United Kingdom. Their research primarily focuses on Medicine and Neuroscience, with significant contributions in subfields such as Physiology, Endocrine and Autonomic Systems, Developmental Neuroscience, Neurology, and Nutrition and Dietetics.

The core topics covered in their work include:

  • Regulation of Appetite and Obesity
  • Adipose Tissue and Metabolism
  • Diet and Metabolism Studies
  • Dietary Effects on Health
  • Neurogenesis and Neuroplasticity Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Biochemical Analysis and Sensing Techniques

Recent papers by Timothy N. C. Wells illustrate an interest in neurogenesis, metabolic regulation, and neurodegenerative diseases. Selected publications include:

  • "Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in Humans," 2020, Cell Reports Medicine
  • "The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice," 2023, EMBO Reports
  • "Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson's Disease," 2022, Cellular and Molecular Neurobiology
  • "Acyl-ghrelin attenuates neurochemical and motor deficits in the 6-OHDA model of Parkinson's disease," 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • "Meal-feeding promotes skeletal growth by ghrelin-dependent enhancement of growth hormone rhythmicity," 2025, Journal of Clinical Investigation

The scientist frequently publishes in specific journals and platforms that align with their research interests. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrine Abstracts
  • Journal of the Endocrine Society
  • Cell Reports Medicine
  • EMBO Reports

Collaborations form a notable part of their research activities. Frequent co-authors comprise:

  • Jeffrey S. Davies
  • Amanda K. E. Hornsby
  • Luke D. Roberts
  • Martina Sassi
  • Alwena H. Morgan

Best Publications

  • Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

    Amanda E. I. Proudfoot;Tracy M. Handel;Zoë Johnson;Elaine K. Lau

  • Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

    Graham Simmons;Paul R. Clapham;Laurent Picard;Robin E. Offord

  • CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

    Michael J Endres;Paul R Clapham;Mark Marsh;Ména Ahuja

  • RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis.

    Clare M. Lloyd;Andrew W. Minto;Martin E. Dorf;Amanda Proudfoot

  • Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses.

    Gabriele S. V. Kuschert;Florence Coulin;Christine A. Power;Amanda E. I. Proudfoot

  • The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness

    Jose-Angel Gonzalo;Clare M. Lloyd;Danyi Wen;Juan P. Albar

  • Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

    Arlene J. Hoogewerf;Gabriele S. V. Kuschert;Amanda E. I. Proudfoot;Frederic Borlat

  • The Platelet Collagen Receptor Glycoprotein VI Is a Member of the Immunoglobulin Superfamily Closely Related to FcαR and the Natural Killer Receptors

    Jeannine M. Clemetson;Janós Polgar;Edith Magnenat;Timothy N.C. Wells

  • Extension of Recombinant Human RANTES by the Retention of the Initiating Methionine Produces a Potent Antagonist

    Amanda E.I. Proudfoot;Christine A. Power;Arlene J. Hoogewerf;Marc-Olivier Montjovent

  • Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

    Matthias Mack;Bruno Luckow;Peter J. Nelson;Josef Cihak

  • Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

    Natalie Signoret;Joanne Oldridge;Annegret Pelchen-Matthews;Per J. Klasse

  • Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor

    János Polgár;Jeannine M. Clemetson;Beate E. Kehrel;Markus Wiedemann

  • CCR5 provides a signal for microbial induced production of IL-12 by CD8 alpha+ dendritic cells.

    J Aliberti;C Reis e Sousa;M Schito;S Hieny

  • Molecular Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA from a Human Basophilic Cell Line

    Christine A. Power;Alexandra Meyer;Karin Nemeth;Kevin B. Bacon

  • Bacterial Lipopolysaccharide Rapidly Inhibits Expression of C-C Chemokine Receptors in Human Monocytes

    Antonio Sica;Alessandra Saccani;Alessandro Borsatti;Christine A. Power

  • HIV-1 Tat protein mimicry of chemokines

    Adriana Albini;Silvano Ferrini;Roberto Benelli;Sabrina Sforzini

  • Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells

    Christine A. Power;Dennis J. Church;Alexandra Meyer;Sami Alouani

  • A novel dimer configuration revealed by the crystal structure at 2.4 Å resolution of human interleukin-5

    Michael V. Milburn;Anne M. Hassell;Millard H. Lambert;Steven R. Jordan

  • A Key Role for Cc Chemokine Receptor 4 in Lipopolysaccharide-Induced Endotoxic Shock

    Yolande Chvatchko;Arlene J. Hoogewerf;Alexandra Meyer;Sami Alouani

  • Kinetics of Eotaxin Generation and Its Relationship to Eosinophil Accumulation in Allergic Airways Disease: Analysis in a Guinea Pig Model In Vivo

    Alison A. Humbles;Dolores M. Conroy;Sylvie Marleau;Sara M. Rankin

Frequent Co-Authors

Amanda E. I. Proudfoot
Amanda E. I. Proudfoot Merck (Germany)
Christine A. Power
Christine A. Power Merck Serono (Italy)
Manuel C. Peitsch
Manuel C. Peitsch Philip Morris International (United States)
Alexander Kapp
Alexander Kapp Hannover Medical School
Kenneth J. Clemetson
Kenneth J. Clemetson University of Bern
Mauro M. Teixeira
Mauro M. Teixeira Universidade Federal de Minas Gerais
Zane B. Andrews
Zane B. Andrews Monash University
Thomas R. Martin
Thomas R. Martin University of Washington
Alain Bernard
Alain Bernard Grenoble Alpes University

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