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Biology and Biochemistry

D-Index
90
Citations
33371
World Ranking
2417
National Ranking
1283

Overview

John A. Cooper is affiliated with Washington University in St. Louis in the United States. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions in several subfields including Cell Biology, Surgery, Pulmonary and Respiratory Medicine, Molecular Biology, and Immunology and Allergy.

The scientist's research focuses on topics related to Cellular Mechanics and Interactions, Cell Adhesion Molecules Research, Ocular Oncology and Treatments, Microtubule and Mitosis Dynamics, Force Microscopy Techniques and Applications, Advanced Fluorescence Microscopy Techniques, and Chronic Obstructive Pulmonary Disease (COPD) Research.

Cooper has published extensively, with frequent appearances in venues such as bioRxiv (Cold Spring Harbor Laboratory), The American Journal of Gastroenterology, Gastrointestinal Endoscopy, Gastroenterology, and CHEST Journal.

Some of the recent publications include:

  • Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation, 2023, The Lancet Diabetes & Endocrinology
  • A randomised trial of a web-based physical activity self-management intervention in COPD, 2021, ERJ Open Research
  • Serum IgG Levels and Risk of COPD Hospitalization, 2020, CHEST Journal
  • Targeting primary and metastatic uveal melanoma with a G protein inhibitor, 2021, Journal of Biological Chemistry
  • Comparative Analysis of CPI-Motif Regulation of Biochemical Functions of Actin Capping Protein, 2020, Biochemistry

Among frequent co-authors are Olivia L. Mooren, Patrick McConnell, Michael D. Onken, Charles D. Evers, and Ada Holyfield. These collaborations reflect a sustained partnership across multiple projects and publications.

Cooper's work, considering the main and subfield topics, addresses various aspects of cellular function and disease, including pulmonary medicine and ocular oncology, indicating a multidisciplinary approach integrating molecular biology techniques with clinical research.

Best Publications

  • Effects of cytochalasin and phalloidin on actin.

    John A. Cooper

  • Actin, a Central Player in Cell Shape and Movement

    Thomas D. Pollard;John A. Cooper

  • Actin and Actin-Binding Proteins. A Critical Evaluation of Mechanisms and Functions

    Thomas D. Pollard;John A. Cooper

  • 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

    R. Wilson;R. Ainscough;K. Anderson;C. Baynes

  • Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

    James E. Bear;Tatyana M. Svitkina;Matthias Krause;Dorothy A. Schafer

  • The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

    Michael L. Dustin;John A. Cooper

  • Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.

    Alissa M. Weaver;Andrei V. Karginov;Andrew W. Kinley;Scott A. Weed

  • Pyrene actin: documentation of the validity of a sensitive assay for actin polymerization.

    John A. Cooper;Simon B. Walker;Thomas D. Pollard

  • Three-dimensional imaging by deconvolution microscopy.

    James G. McNally;Tatiana Karpova;John Cooper;José Angel Conchello

  • Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides.

    Dorothy A. Schafer;Phillip B. Jennings;John A. Cooper

  • Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex

    Scott A. Weed;Andrei V. Karginov;Dorothy A. Schafer;Alissa M. Weaver

  • Control of actin assembly and disassembly at filament ends

    John A Cooper;Dorothy A Schafer

  • Roles for Actin Assembly in Endocytosis

    Olivia L. Mooren;Brian J. Galletta;John A. Cooper

  • THE ROLE OF ACTIN POLYMERIZATION IN CELL MOTILITY

    John A. Cooper

  • Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae.

    Neil R. Adames;John A. Cooper

  • Nicotine Acts as a Pharmacological Chaperone to Up-Regulate Human α4β2 Acetylcholine Receptors

    Alexander Kuryatov;Jie Luo;John Cooper;Jon M. Lindstrom

  • Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation.

    Thomas D. Pollard;John A. Cooper

  • Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin.

    D A Schafer;S R Gill;J A Cooper;J E Heuser

  • Interaction of cortactin and N-WASp with Arp2/3 complex.

    Alissa M. Weaver;John E. Heuser;Andrei V. Karginov;Wei lih Lee

  • Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII

    M Johnston;S Andrews;R Brinkman;J Cooper

Frequent Co-Authors

Thomas D. Pollard
Thomas D. Pollard Yale University
Tatiana S. Karpova
Tatiana S. Karpova National Institutes of Health
Kendall J. Blumer
Kendall J. Blumer Washington University in St. Louis
Alissa M. Weaver
Alissa M. Weaver Vanderbilt University
J. Thomas Parsons
J. Thomas Parsons University of Virginia
Timothy M. Lohman
Timothy M. Lohman Washington University in St. Louis
Elliot L. Elson
Elliot L. Elson Washington University in St. Louis
Gaya K. Amarasinghe
Gaya K. Amarasinghe Washington University in St. Louis
Carl Frieden
Carl Frieden Washington University in St. Louis
John E. Heuser
John E. Heuser Washington University in St. Louis

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