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Biology and Biochemistry

D-Index
57
Citations
12603
World Ranking
13765
National Ranking
5827

Overview

Kendall J. Blumer is affiliated with Washington University in St. Louis in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular and cellular processes related to ocular oncology and retinal disorders.

The main fields of study for Blumer include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, Blumer extensively investigates several subfields such as:

  • Molecular Biology
  • Ophthalmology
  • Cell Biology
  • Immunology and Allergy
  • Cancer Research

Their research topics concentrate on:

  • Ocular Oncology and Treatments
  • Retinal Development and Disorders
  • Cell Adhesion Molecules Research
  • Receptor Mechanisms and Signaling
  • Cellular transport and secretion
  • Protein Structure and Dynamics
  • Ubiquitin and proteasome pathways

Blumer has authored several papers, among which are:

  • "Macrophage secretion of miR-106b-5p causes renin-dependent hypertension" (2020) published in Nature Communications
  • "Chloroquine Sensitizes GNAQ/11-mutated Melanoma to MEK1/2 Inhibition" (2020) published in Clinical Cancer Research
  • "Targeting primary and metastatic uveal melanoma with a G protein inhibitor" (2021) published in Journal of Biological Chemistry
  • "Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma" (2021) published in Journal of Biological Chemistry
  • "Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium" (2021) published in Molecular Biology of the Cell

Frequent co-authors contributing extensively alongside Blumer include:

  • Michael D. Onken
  • Kevin M. Kaltenbronn
  • Carol M. Makepeace
  • Kisha Piggott
  • Tyson D. Todd

The scholar's work appears predominantly in journals such as:

  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Clinical Cancer Research

Best Publications

  • A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

    Carol A. Lange-Carter;Chris M. Pleiman;Anne M. Gardner;Kendall J. Blumer

  • RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

    Ned Watson;Maurine E. Linder;Kirk M. Druey;John H. Kehrl

  • Diversity in function and regulation of MAP kinase pathways

    Kendall J. Blumer;Gary L. Johnson

  • Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

    Kirk M. Druey;Kendall J. Blumer;Kendall J. Blumer;Veronica H. Kang;Veronica H. Kang;John H. Kehrl;John H. Kehrl

  • Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

    K Mary Tang;Guang-rong Wang;Ping Lu;Richard H Karas

  • RGS2/G0S8 is a selective inhibitor of Gqα function

    Scott P. Heximer;Ned Watson;Maurine E. Linder;Kendall J. Blumer

  • Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice

    Scott P. Heximer;Russell H. Knutsen;Xiaoguang Sun;Kevin M. Kaltenbronn

  • The carboxy-terminal segment of the yeast α-factor receptor is a regulatory domain

    Johanna E. Reneke;Kendall J. Blumer;William E. Courchesne;Jeremy Thorner

  • G-protein-coupled receptors function as oligomers in vivo

    Mark C. Overton;Kendall J. Blumer

  • Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency

    Gilles Faury;Mylène Pezet;Russell H. Knutsen;Walter A. Boyle

  • Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1.

    S. Richard;Dongyin Yu;K. J. Blumer;D. Hausladen

  • The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.

    K J Blumer;J E Reneke;J Thorner

  • RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

    Jason H. Rogers;Praveen Tamirisa;Attila Kovacs;Carla Weinheimer

  • Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

    Tobias B. Huber;Christopher Kwoh;Hui Wu;Katsuhiko Asanuma

  • G Protein Selectivity Is a Determinant of RGS2 Function

    Scott P. Heximer;Sreesha P. Srinivasa;Leah S. Bernstein;Jennifer L. Bernard

  • Plasma Membrane Localization is Required for RGS4 Function in Saccharomyces cerevisiae

    Sreesha P. Srinivasa;Leah S. Bernstein;Kendall J. Blumer;Maurine E. Linder

  • Mechanism of RGS4, a GTPase-activating Protein for G Protein α Subunits *

    Sreesha P. Srinivasa;Ned Watson;Mark C. Overton;Kendall J. Blumer

  • Oligomerization, Biogenesis, and Signaling Is Promoted by a Glycophorin A-like Dimerization Motif in Transmembrane Domain 1 of a Yeast G Protein-coupled Receptor

    Mark C. Overton;Sharon L. Chinault;Kendall J. Blumer

  • Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system.

    Christopher Larminie;Paul Murdock;Jean-Philippe Walhin;Malcolm Duckworth

  • Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.

    Kendall J. Blumer;Jeremy Thorner

Frequent Co-Authors

John A. Cooper
John A. Cooper Washington University in St. Louis
Maurine E. Linder
Maurine E. Linder Cornell University
Anthony J. Muslin
Anthony J. Muslin Washington University in St. Louis
Jeremy Thorner
Jeremy Thorner University of California, Berkeley
Robert P. Mecham
Robert P. Mecham Washington University in St. Louis
Martin McMahon
Martin McMahon Huntsman Cancer Institute
Friedrich C. Luft
Friedrich C. Luft Charité - University Medicine Berlin
Gregory R. Bowman
Gregory R. Bowman Washington University in St. Louis
John H. Kehrl
John H. Kehrl National Institutes of Health
Thomas H. Steinberg
Thomas H. Steinberg Washington University in St. Louis

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