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Maurine E. Linder

Maurine E. Linder

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
14456
World Ranking
12409
National Ranking
5314

Overview

Maurine E. Linder is affiliated with Cornell University in the United States and primarily conducts research in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans multiple subfields including Molecular Biology, Oncology, Immunology, Cancer Research, and Pharmacology.

The scientist's research focuses on various main topics, notably:

  • Inflammasome and immune disorders
  • Histone Deacetylase Inhibitors Research
  • Peptidase Inhibition and Analysis
  • Glycosylation and Glycoproteins Research
  • Ubiquitin and proteasome pathways
  • Heme Oxygenase-1 and Carbon Monoxide
  • Signaling Pathways in Disease

Their recent published papers include the following:

  • "A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis," 2020, Nature
  • "Mechanisms and functions of protein S-acylation," 2024, Nature Reviews Molecular Cell Biology
  • "Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target," 2022, Nature Chemical Biology
  • "Substrate recruitment by zDHHC protein acyltransferases," 2021, Open Biology
  • "NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation," 2024, Cell Reports

Maurine E. Linder frequently collaborates with several researchers, including:

  • Martin Ian P. Malgapo
  • Hening Lin
  • Min Yang
  • Xuan Lü
  • Severin Lechner

Their publications regularly appear in venues such as:

  • Nature Chemical Biology
  • ACS Chemical Biology
  • Nature
  • Nature Reviews Molecular Cell Biology
  • Open Biology

Best Publications

  • Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.

    David E. Coleman;Albert M. Berghuis;Ethan Lee;Maurine E. Linder

  • RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

    Ned Watson;Maurine E. Linder;Kirk M. Druey;John H. Kehrl

  • Lipid-dependent targeting of G proteins into rafts.

    Serge Moffett;Deborah A. Brown;Maurine E. Linder

  • Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel

    Kevin D. Wickman;Jorge A. Iñiguez-Lluhi;Philip A. Davenport;Ronald Taussig

  • Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

    Sandra Lobo;Wendy K. Greentree;Maurine E. Linder;Robert J. Deschenes

  • Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases

    David A. Mitchell;Anant Vasudevan;Maurine E. Linder;Robert J. Deschenes

  • Signalling functions of protein palmitoylation.

    Julianne T. Dunphy;Maurine E. Linder

  • RGS2/G0S8 is a selective inhibitor of Gqα function

    Scott P. Heximer;Ned Watson;Maurine E. Linder;Kendall J. Blumer

  • DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras

    John T. Swarthout;Sandra Lobo;Lynn Farh;Monica R. Croke

  • Protein lipidation: Function and mechanism of palmitoylation

    Marissa J. Nadolski;Maurine E. Linder

  • New insights into the mechanisms of protein palmitoylation.

    Maurine E. Linder;Robert J. Deschenes

  • Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

    Maurine E. Linder;Douglas A. Ewald;Richard J. Miller;Alfred G. Gilman

  • DHHC Protein S-Acyltransferases Use Similar Ping-Pong Kinetic Mechanisms but Display Different Acyl-CoA Specificities

    Benjamin C. Jennings;Maurine E. Linder

  • G-protein Palmitoyltransferase Activity Is Enriched in Plasma Membranes

    Julianne T. Dunphy;Wendy K. Greentree;Carol L. Manahan;Maurine E. Linder

  • The Thrombospondin Receptor Integrin-associated Protein (CD47) Functionally Couples to Heterotrimeric Gi*

    William A. Frazier;Ai-Guo Gao;Julie Dimitry;Jun Chung

  • SNAP-25 Palmitoylation and Plasma Membrane Targeting Require a Functional Secretory Pathway

    Susana Gonzalo;Maurine E. Linder

  • 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro

    Benjamin C. Jennings;Marissa J. Nadolski;Yiping Ling;Meredith Beckham Baker

  • G Protein Selectivity Is a Determinant of RGS2 Function

    Scott P. Heximer;Sreesha P. Srinivasa;Leah S. Bernstein;Jennifer L. Bernard

  • A STAT3 palmitoylation cycle promotes T H 17 differentiation and colitis

    Mingming Zhang;Mingming Zhang;Lixing Zhou;Yuejie Xu;Min Yang

  • Plasma Membrane Localization is Required for RGS4 Function in Saccharomyces cerevisiae

    Sreesha P. Srinivasa;Leah S. Bernstein;Kendall J. Blumer;Maurine E. Linder

Frequent Co-Authors

Kendall J. Blumer
Kendall J. Blumer Washington University in St. Louis
Hening Lin
Hening Lin Howard Hughes Medical Institute
Vivek Mittal
Vivek Mittal Cornell University
John R. Hepler
John R. Hepler Emory University
Hui Jing
Hui Jing Hunan Normal University
Tohru Kozasa
Tohru Kozasa University of Illinois at Chicago
Alfred G. Gilman
Alfred G. Gilman The University of Texas Southwestern Medical Center
Donald W. Hilgemann
Donald W. Hilgemann The University of Texas Southwestern Medical Center
Patrick J. Casey
Patrick J. Casey National University of Singapore
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis

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