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Biology and Biochemistry
Singapore
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
28720
World Ranking
3125
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Singapore Leader Award
  • 2025 - Research.com Biology and Biochemistry in Singapore Leader Award
  • 2023 - Research.com Biology and Biochemistry in Singapore Leader Award
  • 2022 - Research.com Biology and Biochemistry in Singapore Leader Award

Overview

Patrick J. Casey is affiliated with the National University of Singapore in Singapore. Their research spans multiple fields predominantly in Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields including Pulmonary and Respiratory Medicine, Molecular Biology, Cell Biology, Oncology, and Surgery.

Their work covers a range of specialized topics, notably:

  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Protein Kinase Regulation and GTPase Signaling
  • Hippo pathway signaling and YAP/TAZ
  • Aortic Disease and Treatment Approaches
  • Global Health Workforce Issues
  • Esophageal Cancer Research and Treatment

Patrick J. Casey has contributed to a variety of recent research papers, including:

  • The emerging roles of Gα12/13 proteins on the hallmarks of cancer in solid tumors, 2021, Oncogene
  • Principal components analysis and K-means clustering of till geochemical data: Mapping and targeting of prospective areas for lithium exploration in Västernorrland Region, Sweden, 2024, Ore Geology Reviews
  • Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal, 2020, Oncogene
  • Symptoms of gluten ingestion in patients with non-celiac gluten sensitivity: A randomized clinical trial, 2020, Nutrition
  • Safety and effectiveness of single ProGlide vascular access in patients undergoing endovascular aneurysm repair, 2020, Journal of Vascular Surgery

Their frequent co-authors include:

  • Samuel Jessula
  • Claudia Côté
  • Mei Wang
  • Christine Herman
  • Garrett McDougall

Patrick J. Casey's work has been published across several journals, with multiple papers appearing in the following venues:

  • Journal of Vascular Surgery
  • Annals of Vascular Surgery
  • British journal of surgery
  • UNC Libraries
  • Oncogene

Best Publications

  • Protein prenylation: molecular mechanisms and functional consequences.

    Fang L. Zhang;Patrick J. Casey

  • p21ras is modified by a farnesyl isoprenoid.

    Patrick J. Casey;Patricia A. Solski;Channing J. der;Janice E. Buss

  • Protein lipidation in cell signaling

    Patrick J. Casey

  • Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.

    Yuval Reiss;Joseph L. Goldstein;Miguel C. Seabra;Patrick J. Casey

  • Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

    Julie A. Pitcher;James Inglese;Joyce B. Higgins;Jeffery L. Arriza

  • G protein involvement in receptor-effector coupling.

    P J Casey;A G Gilman

  • G proteins control diverse pathways of transmembrane signaling.

    Michael Freissmuth;Patrick J. Casey;Alfred G. Gilman

  • RGS10 is a selective activator of G alpha i GTPase activity.

    Timothy W. Hunt;Timothy A. Fields;Patrick J. Casey;Ernest G. Peralta

  • Protein prenylation: unique fats make their mark on biology

    Mei Wang;Patrick J. Casey;Patrick J. Casey

  • Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution

    Hee-Won Park;Sobha R. Boduluri;John F. Moomaw;Patrick J. Casey

  • Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit

    Miguel C. Seabra;Yuval Reiss;Patrick J. Casey;Michael S. Brown

  • Post-prenylation-processing enzymes as new targets in oncogenesis

    Ann M. Winter-Vann;Patrick J. Casey

  • Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation

    Chou Long Huang;Paul A. Slesinger;Patrick J. Casey;Yuh Nung Jan

  • Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins

    Janice E. Buss;Susanne M. Mumby;Patrick J. Casey;Alfred G. Gilman

  • Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins.

    Timothy A. Fields;Patrick J. Casey

  • Gz, a guanine nucleotide-binding protein with unique biochemical properties.

    Patrick J. Casey;Henry K. W. Fong;Melvin I. Simon;Alfred G. Gilman

  • G protein gamma subunits contain a 20-carbon isoprenoid.

    Susanne M. Mumby;Patrick J. Casey;Alfred G. Gilman;Stephen Gutowski

  • Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.

    T.S. Reid;K.L. Terry;P.J. Casey;L.S. Beese

  • Site-specific analysis of protein S-acylation by resin-assisted capture

    Michael T. Forrester;Douglas T. Hess;J. Will Thompson;Rainbo C. Hultman

  • Biochemistry of protein prenylation.

    Patrick J. Casey

Frequent Co-Authors

Stephen G. Young
Stephen G. Young University of California, Los Angeles
Alfred G. Gilman
Alfred G. Gilman The University of Texas Southwestern Medical Center
Lorena S. Beese
Lorena S. Beese Duke University
Christopher B. Newgard
Christopher B. Newgard Duke University
Carol A. Fierke
Carol A. Fierke Texas A&M University
Vinay Tergaonkar
Vinay Tergaonkar Agency for Science, Technology and Research
Alexander Tropsha
Alexander Tropsha University of North Carolina at Chapel Hill
Yoshitaka Fukada
Yoshitaka Fukada University of Tokyo
Yehia Daaka
Yehia Daaka University of Florida
Michael Freissmuth
Michael Freissmuth Medical University of Vienna

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