2023 - Research.com Biology and Biochemistry in Singapore Leader Award
2022 - Research.com Biology and Biochemistry in Singapore Leader Award
His primary areas of investigation include Biochemistry, Prenylation, Cell biology, G protein and Farnesyltransferase. His works in Protein subunit, G alpha subunit, Cysteine, Heterotrimeric G protein and Serine are all subjects of inquiry into Biochemistry. Patrick J. Casey is studying Protein prenylation, which is a component of Prenylation.
His biological study spans a wide range of topics, including Spindle apparatus, Protein lipidation and Cell growth. His work deals with themes such as Binding protein, Binding site and Effector, which intersect with G protein. The various areas that Patrick J. Casey examines in his Farnesyltransferase study include Crystallography, Transferase, Substrate and Actin.
The scientist’s investigation covers issues in Biochemistry, Cell biology, Prenylation, G protein and Farnesyltransferase. His study on Biochemistry is mostly dedicated to connecting different topics, such as Stereochemistry. His studies in Cell biology integrate themes in fields like Cancer cell, Autophagy and Cell growth.
His Prenylation research is multidisciplinary, incorporating elements of Peptide sequence, Methylation, Lipid modification and Membrane protein. His research investigates the connection between G protein and topics such as Effector that intersect with issues in Receptor. His Farnesyltransferase study integrates concerns from other disciplines, such as Residue, Transferase, Substrate and Ternary complex.
Patrick J. Casey focuses on Cancer research, Cell biology, Cancer, Cancer cell and GNA13. His Cancer research research incorporates themes from Gene knockdown, KRAS, LNCaP, Tumor progression and Gene silencing. His work investigates the relationship between LNCaP and topics such as HEK 293 cells that intersect with problems in Heterotrimeric G protein and G protein.
His Cell biology research includes elements of Autophagy, Cell cycle and Prenylation. To a larger extent, he studies Biochemistry with the aim of understanding Prenylation. The study incorporates disciplines such as Statin, Cancer stem cell, Hippo signaling pathway, Metastasis and In vivo in addition to Cancer cell.
His main research concerns Cell biology, Prenylation, Cancer research, Cancer and Autophagy. Patrick J. Casey has researched Cell biology in several fields, including Simvastatin, Lipid modification and Protein prenylation. Protein prenylation is a subfield of Biochemistry that he explores.
His Prenylation research is multidisciplinary, relying on both GTPase, Cdc42 GTP-Binding Protein, CDC42, Signal transduction and RAC1. His Cancer research study combines topics in areas such as GNA13, Conditional gene knockout, Molecular biology and Heterotrimeric G protein, G protein. His Cancer research includes themes of Apoptosis, Cell signaling and Cell.
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Protein prenylation: molecular mechanisms and functional consequences.
Fang L. Zhang;Patrick J. Casey.
Annual Review of Biochemistry (1996)
p21ras is modified by a farnesyl isoprenoid.
Patrick J. Casey;Patricia A. Solski;Channing J. der;Janice E. Buss.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Protein lipidation in cell signaling
Patrick J. Casey.
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
Yuval Reiss;Joseph L. Goldstein;Miguel C. Seabra;Patrick J. Casey.
Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.
Julie A. Pitcher;James Inglese;Joyce B. Higgins;Jeffery L. Arriza.
G protein involvement in receptor-effector coupling.
P J Casey;A G Gilman.
Journal of Biological Chemistry (1988)
G proteins control diverse pathways of transmembrane signaling.
Michael Freissmuth;Patrick J. Casey;Alfred G. Gilman.
The FASEB Journal (1989)
RGS10 is a selective activator of G alpha i GTPase activity.
Timothy W. Hunt;Timothy A. Fields;Patrick J. Casey;Ernest G. Peralta.
Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution
Hee-Won Park;Sobha R. Boduluri;John F. Moomaw;Patrick J. Casey.
Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit
Miguel C. Seabra;Yuval Reiss;Patrick J. Casey;Michael S. Brown.
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