What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Biochemistry, Prenylation, Cell biology, G protein and Farnesyltransferase.
His works in Protein subunit, G alpha subunit, Cysteine, Heterotrimeric G protein and Serine are all subjects of inquiry into Biochemistry.
Patrick J. Casey is studying Protein prenylation, which is a component of Prenylation.
His biological study spans a wide range of topics, including Spindle apparatus, Protein lipidation and Cell growth.
His work deals with themes such as Binding protein, Binding site and Effector, which intersect with G protein.
The various areas that Patrick J. Casey examines in his Farnesyltransferase study include Crystallography, Transferase, Substrate and Actin.
His most cited work include:
- Protein prenylation: molecular mechanisms and functional consequences. (1743 citations)
- Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides. (714 citations)
- Protein lipidation in cell signaling (707 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Biochemistry, Cell biology, Prenylation, G protein and Farnesyltransferase.
His study on Biochemistry is mostly dedicated to connecting different topics, such as Stereochemistry.
His studies in Cell biology integrate themes in fields like Cancer cell, Autophagy and Cell growth.
His Prenylation research is multidisciplinary, incorporating elements of Peptide sequence, Methylation, Lipid modification and Membrane protein.
His research investigates the connection between G protein and topics such as Effector that intersect with issues in Receptor.
His Farnesyltransferase study integrates concerns from other disciplines, such as Residue, Transferase, Substrate and Ternary complex.
He most often published in these fields:
- Biochemistry (46.99%)
- Cell biology (44.58%)
- Prenylation (36.14%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (17.67%)
- Cell biology (44.58%)
- Cancer (11.24%)
In recent papers he was focusing on the following fields of study:
Patrick J. Casey focuses on Cancer research, Cell biology, Cancer, Cancer cell and GNA13.
His Cancer research research incorporates themes from Gene knockdown, KRAS, LNCaP, Tumor progression and Gene silencing.
His work investigates the relationship between LNCaP and topics such as HEK 293 cells that intersect with problems in Heterotrimeric G protein and G protein.
His Cell biology research includes elements of Autophagy, Cell cycle and Prenylation.
To a larger extent, he studies Biochemistry with the aim of understanding Prenylation.
The study incorporates disciplines such as Statin, Cancer stem cell, Hippo signaling pathway, Metastasis and In vivo in addition to Cancer cell.
Between 2012 and 2021, his most popular works were:
- Protein prenylation: unique fats make their mark on biology (214 citations)
- Protein prenylation: unique fats make their mark on biology (214 citations)
- MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. (59 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Prenylation, Cancer research, Cancer and Autophagy.
Patrick J. Casey has researched Cell biology in several fields, including Simvastatin, Lipid modification and Protein prenylation.
Protein prenylation is a subfield of Biochemistry that he explores.
His Prenylation research is multidisciplinary, relying on both GTPase, Cdc42 GTP-Binding Protein, CDC42, Signal transduction and RAC1.
His Cancer research study combines topics in areas such as GNA13, Conditional gene knockout, Molecular biology and Heterotrimeric G protein, G protein.
His Cancer research includes themes of Apoptosis, Cell signaling and Cell.
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