D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 109 Citations 41,295 437 World Ranking 467 National Ranking 225
Biology and Biochemistry D-index 117 Citations 45,502 528 World Ranking 496 National Ranking 339

Research.com Recognitions

Awards & Achievements

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

1991 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of investigation include Biochemistry, Phospholipase A2, Enzyme, Molecular biology and Stereochemistry. As part of one scientific family, Michael H. Gelb deals mainly with the area of Biochemistry, narrowing it down to issues related to the Cell biology, and often Cell culture. His Phospholipase A2 research incorporates themes from Phospholipase, Inflammation, Arachidonic acid, Eicosanoid and Binding site.

His work deals with themes such as Cloning, Recombinant DNA and Krabbe disease, which intersect with Enzyme. His Molecular biology study combines topics in areas such as Laminopathy, LMNA, Escherichia coli, Receptor and Phosphorylation. His Stereochemistry research also works with subjects such as

  • Hydrolase that intertwine with fields like Protein structure,
  • Chemical synthesis which connect with Structure–activity relationship.

His most cited work include:

  • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags (4313 citations)
  • Interfacial catalysis: the mechanism of phospholipase A2 (625 citations)
  • Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction (599 citations)

What are the main themes of his work throughout his whole career to date?

Michael H. Gelb spends much of his time researching Biochemistry, Phospholipase A2, Enzyme, Stereochemistry and Newborn screening. His Biochemistry study combines topics from a wide range of disciplines, such as Molecular biology and Cell biology. His Phospholipase A2 study integrates concerns from other disciplines, such as Phospholipid, Phospholipase, Inflammation, Immunology and Arachidonic acid.

His Enzyme study incorporates themes from In vitro and Trypanosoma brucei. His Stereochemistry research is multidisciplinary, incorporating elements of Peptide and Active site. The study incorporates disciplines such as Dried blood, Tandem mass spectrometry, Krabbe disease and Dried blood spot in addition to Newborn screening.

He most often published in these fields:

  • Biochemistry (44.62%)
  • Phospholipase A2 (25.27%)
  • Enzyme (24.73%)

What were the highlights of his more recent work (between 2014-2021)?

  • Newborn screening (13.26%)
  • Tandem mass spectrometry (10.22%)
  • Dried blood (4.30%)

In recent papers he was focusing on the following fields of study:

Michael H. Gelb mostly deals with Newborn screening, Tandem mass spectrometry, Dried blood, Biochemistry and Chromatography. His Newborn screening research is multidisciplinary, relying on both Enzyme assay, Multiplex, Krabbe disease and Dried blood spot. His Tandem mass spectrometry study also includes

  • Molecular biology and related Reference range,
  • Mucopolysaccharidosis which intersects with area such as Glycosaminoglycan.

His Dried blood research incorporates themes from Pathology, Spots, Gastroenterology, Enzyme and Internal medicine. Michael H. Gelb has included themes like Selected reaction monitoring, Cell-Derived Microparticles and Stereochemistry in his Biochemistry study. As a part of the same scientific study, he usually deals with the Phospholipase A2, concentrating on Cell biology and frequently concerns with Calcium and Psoriasis.

Between 2014 and 2021, his most popular works were:

  • Computational protein design enables a novel one-carbon assimilation pathway (155 citations)
  • Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA (115 citations)
  • Pilot study of newborn screening for six lysosomal storage diseases using Tandem Mass Spectrometry. (83 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Newborn screening, Biochemistry, Phospholipase A2, Dried blood and Tandem mass spectrometry are his primary areas of study. His studies deal with areas such as Dried blood spot, Pseudodeficiency alleles and Leukodystrophy, Krabbe disease as well as Newborn screening. Michael H. Gelb interconnects Cell-Derived Microparticles, Stereochemistry and Molecular biology in the investigation of issues within Biochemistry.

Michael H. Gelb has researched Phospholipase A2 in several fields, including Inflammation, Immunology, Docosahexaenoic acid and Cell biology. The various areas that Michael H. Gelb examines in his Dried blood study include Gastroenterology, Enzyme assay and Multiplex. His Tandem mass spectrometry study combines topics in areas such as Fabry disease, Internal medicine, Mucopolysaccharidosis and Enzyme.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

Steven P. Gygi;Beate Rist;Scott A. Gerber;Frantisek Turecek.
Nature Biotechnology (1999)

6439 Citations

Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction

Justin B. Siegel;Alexandre Zanghellini;Helena M. Lovick;Gert Kiss.
Science (2010)

966 Citations

Interfacial catalysis: the mechanism of phospholipase A2

David L. Scott;Steven P. White;Zbyszek Otwinowski;Wei Yuan.
Science (1990)

872 Citations

Biochemistry and physiology of mammalian secreted phospholipases A2.

Gérard Lambeau;Michael H Gelb.
Annual Review of Biochemistry (2008)

579 Citations

Prenyl proteins in eukaryotic cells: a new type of membrane anchor

John A. Glomset;Michael H. Gelb;Christopher C. Farnsworth.
Trends in Biochemical Sciences (1990)

575 Citations

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

I. P. Street;Hung-Kuei Lin;F. Laliberte;Farideh Ghomashchi.
Biochemistry (1993)

494 Citations

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

Luc H. Boudreau;Anne Claire Duchez;Nathalie Cloutier;Denis Soulet.
Blood (2014)

469 Citations

Interfacial Enzymology: The Secreted Phospholipase A2-Paradigm

Otto G. Berg;Michael H. Gelb;Ming-Daw Tsai;Mahendra Kumar Jain.
Chemical Reviews (2001)

452 Citations

Fluoro ketone inhibitors of hydrolytic enzymes.

Michael H. Gelb;John P. Svaren;Robert H. Abeles.
Biochemistry (1985)

451 Citations

Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.

David L. Scott;Zbyszek Otwinowski;Michael H. Gelb;Paul B. Sigler.
Science (1990)

429 Citations

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