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Wesley C. Van Voorhis

Wesley C. Van Voorhis

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
17717
World Ranking
4870
National Ranking
2336

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Wesley C. Van Voorhis is affiliated with the University of Washington in the United States. Their research spans a significant body of work in medicine, with notable contributions in materials chemistry, infectious diseases, parasitology, molecular biology, and public health, environmental and occupational health.

The scientist's research interests focus on key topics such as crystallization and solubility studies, X-ray diffraction in crystallography, parasitic infections and diagnostics, SARS-CoV-2 and COVID-19 research, Toxoplasma gondii research studies, mosquito-borne diseases and control, as well as animal virus infection studies.

Recent publications by Wesley C. Van Voorhis include:

  • SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern, 2021, Science
  • Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants, 2021, Science
  • SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape, 2022, Cell Host & Microbe
  • Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines, 2021, Cell
  • Accurate de novo design of membrane-traversing macrocycles, 2022, Cell

Frequent co-authors collaborating with Wesley C. Van Voorhis are:

  • Ryan Choi
  • Lance Stewart
  • Gaurav Bhardwaj
  • Jacob O'Connor
  • Stephen Rettie

The scientist has published extensively in several venues, including:

  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
  • Acta Crystallographica Section F Structural Biology Communications
  • PLoS ONE

Wesley C. Van Voorhis holds the distinction of being a member of the Association of American Physicians. The scope of their work demonstrates engagement with both fundamental and applied aspects of infectious disease research as well as structural biology.

Best Publications

  • Chemical genetics of Plasmodium falciparum.

    W. Armand Guiguemde;Anang A. Shelat;David Bouck;Sandra Duffy

  • Malaria medicines: a glass half full?

    Timothy N. C. Wells;Rob Hooft van Huijsduijnen;Wesley C. Van Voorhis

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.

    Matthew McCallum;Jessica Bassi;Anna De Marco;Alex Chen

  • Genomic-scale prioritization of drug targets: the TDR Targets database

    Fernán Agüero;Bissan Al-Lazikani;Martin Aslett;Matthew Berriman

  • Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants.

    Matthew McCallum;Alexandra C Walls;Kaitlin R Sprouse;John E Bowen

  • Therapeutic intervention based on protein prenylation and associated modifications

    Michael H Gelb;Lucas Brunsveld;Christine A Hrycyna;Susan Michaelis

  • Heterologous expression of proteins from Plasmodium falciparum: Results from 1000 genes

    Christopher Mehlin;Erica Boni;Frederick S Buckner;Linnea Engel

  • Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.

    Laxman Nallan;Kevin D. Bauer;Pravin Bendale;Kasey Rivas

  • Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection.

    Arturo Centurion-Lara;Rebecca E. LaFond;Karin Hevner;Charmie Godornes

  • Treponema pallidum Major Sheath Protein Homologue Tpr K Is a Target of Opsonic Antibody and the Protective Immune Response

    Arturo Centurion-Lara;Christa Castro;Lynn Barrett;Caroline Cameron

  • Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.

    Kayode K Ojo;Eric T Larson;Katelyn R Keyloun;Lisa J Castaneda

  • Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

    Gregory J. Crowther;Dhanasekaran Shanmugam;Santiago J. Carmona;Maria A. Doyle

  • Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics

    Michael H. Gelb;Wesley C. Van Voorhis;Frederick S. Buckner;Kohei Yokoyama

  • Opsonic Potential, Protective Capacity, and Sequence Conservation of the Treponema pallidum subspecies pallidum Tp92

    Caroline E. Cameron;Sheila A. Lukehart;Christa Castro;Barbara Molini

  • Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.

    Alexandra C. Walls;Marcos C. Miranda;Alexandra Schäfer;Minh N. Pham

  • Novel paradigms for drug discovery: computational multitarget screening

    Ekachai Jenwitheesuk;Ekachai Jenwitheesuk;Jeremy A. Horst;Kasey L. Rivas;Wesley C. Van Voorhis

  • Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation.

    Richard T. Eastman;Frederick S. Buckner;Kohei Yokoyama;Michael H. Gelb

  • SARS-CoV-2 immune evasion by variant B.1.427/B.1.429

    Matthew McCallum;Jessica Bassi;Anna De Marco;Alex Chen

  • TDR Targets: a chemogenomics resource for neglected diseases

    María P. Magariños;Santiago J. Carmona;Gregory J. Crowther;Stuart A. Ralph

Frequent Co-Authors

Frederick S. Buckner
Frederick S. Buckner University of Washington
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Christophe L. M. J. Verlinde
Christophe L. M. J. Verlinde University of Washington
Ethan A. Merritt
Ethan A. Merritt University of Washington
Michael H. Gelb
Michael H. Gelb University of Washington
Wim G. J. Hol
Wim G. J. Hol University of Washington
Sheila A. Lukehart
Sheila A. Lukehart University of Washington
Andrew D. Hamilton
Andrew D. Hamilton New York University
Andrew Hemphill
Andrew Hemphill University of Bern
Marilyn Parsons
Marilyn Parsons University of Washington

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