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Genetics

D-Index
67
Citations
17769
World Ranking
2522
National Ranking
1127

Overview

Peter J. Myler is affiliated with Seattle Children's Hospital in the United States. Their research spans several interconnected areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, epidemiology, infectious diseases, genetics, and public health-related disciplines.

Their work covers multiple topics including Trypanosoma species research and its implications, leishmaniasis studies, biochemical and molecular research, enzyme structure and function, genomics and phylogenetic studies, RNA and protein synthesis mechanisms, and aspects related to antibiotic resistance in bacteria.

Recent publications by Peter J. Myler include:

  • HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction, 2020, Proceedings of the National Academy of Sciences
  • Genome instability drives epistatic adaptation in the human pathogen Leishmania, 2021, Proceedings of the National Academy of Sciences
  • In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19, 2021, Scientific Reports
  • Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts, 2023, Nature Communications
  • Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in Leishmania, 2021, mSphere

Peter J. Myler frequently collaborates with several researchers, including:

  • Bart L. Staker
  • Thomas E. Edwards
  • Sandhya Subramanian
  • David M. Dranow
  • Wesley C. Van Voorhis

Their publications are commonly found in venues such as:

  • Acta Crystallographica Section F Structural Biology Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Scientific Reports
  • Microbiology Resource Announcements

Peter J. Myler's research integrates aspects of molecular biology with epidemiological and clinical concerns, particularly focusing on pathogens like Trypanosoma and Leishmania species. This multidisciplinary approach encompasses structural biology, genomic analysis, and biochemical mechanisms with broader public health implications.

Best Publications

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • The genome of the kinetoplastid parasite, Leishmania major.

    Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  • TriTrypDB: a functional genomic resource for the Trypanosomatidae

    Martin Aslett;Cristina Aurrecoechea;Matthew Berriman;John Brestelli

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • Biological and structural characterization of a host-adapting amino acid in influenza virus.

    Shinya Yamada;Masato Hatta;Bart L. Staker;Shinji Watanabe

  • Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region.

    Santiago Martı́nez-Calvillo;Santiago Martı́nez-Calvillo;Shaofeng Yan;Shaofeng Yan;Dan Nguyen;Mark Fox

  • Health innovation networks to help developing countries address neglected diseases.

    Carlos Medicis Morel;Tara Acharya;Denis Broun;Ajit Dangi

  • LEISHMANIA MAJOR FRIEDLIN CHROMOSOME 1 HAS AN UNUSUAL DISTRIBUTION OF PROTEIN-CODING GENES

    Peter J. Myler;Lindsey Audleman;Theo deVos;Greg Hixson

  • GeneDB—an annotation database for pathogens

    Flora J. Logan-Klumpler;Nishadi De Silva;Ulrike Boehme;Matthew B Rogers

  • Heterologous expression of proteins from Plasmodium falciparum: Results from 1000 genes

    Christopher Mehlin;Erica Boni;Frederick S Buckner;Linnea Engel

  • Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates

    Susan M Kraemer;Sue A Kyes;Gautam Aggarwal;Amy L Springer

  • A comprehensive analysis of Trypanosoma brucei mitochondrial proteome.

    Aswini K. Panigrahi;Yuko Ogata;Alena Zíková;Atashi Anupama

  • Transcription Initiation and Termination on Leishmania major Chromosome 3

    Santiago Martínez-Calvillo;Dan Nguyen;Kenneth Stuart;Peter J. Myler;Peter J. Myler

  • Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation

    A. Saxena;T. Lahav;N. Holland;G. Aggarwal

  • Histone acetylations mark origins of polycistronic transcription in Leishmania major

    Sean Thomas;Amanda Green;Nancy R Sturm;David A Campbell

  • Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

    Henri G.A.M. van Luenen;Carol Farris;Carol Farris;Sabrina Jan;Paul-Andre Genest

  • Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei

    Bryan C Jensen;Dhileep Sivam;Dhileep Sivam;Charles T Kifer;Peter J Myler;Peter J Myler

  • Molecular organization of Leishmania RNA virus 1.

    Kenneth D. Stuart;Reitha Weeks;Lys Guilbride;Peter J. Myler

  • Mitochondrial Complexes in Trypanosoma brucei A Novel Complex and a Unique Oxidoreductase Complex

    Aswini K. Panigrahi;Alena Zíková;Rachel A. Dalley;Nathalie Acestor

  • Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania

    T. Lahav;D. Sivam;H. Volpin;M. Ronen

Frequent Co-Authors

Kenneth Stuart
Kenneth Stuart University of Washington
Wesley C. Van Voorhis
Wesley C. Van Voorhis University of Washington
Marilyn Parsons
Marilyn Parsons University of Washington
Stephen M. Beverley
Stephen M. Beverley Washington University in St. Louis
Allan Saul
Allan Saul Burnet Institute
Wim G. J. Hol
Wim G. J. Hol University of Washington
Lance Stewart
Lance Stewart University of Washington
Frederick S. Buckner
Frederick S. Buckner University of Washington
Najib M. El-Sayed
Najib M. El-Sayed University of Maryland, College Park
Matthew Berriman
Matthew Berriman University of Glasgow

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